Patents by Inventor Yeong-Mi Mun

Yeong-Mi Mun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9585945
    Abstract: The present invention relates to a composition for preventing or treating an autoimmune disease comprising, as an active ingredient, PINK1 protein or polynucleotide encoding the same. The PINK1 protein according to the present invention inhibits the activity of Th17, promotes the activity of a regulatory T cell (Treg), and increases autophagy in Treg cells, thereby controlling excessive immune responses. Therefore, the PINK1 protein can be effectively used as a pharmaceutical composition or an immunosuppressant, which is capable of preventing or treating an autoimmune disease, such as arthritis, and the like, caused by dysregulation of various kinds of immune responses.
    Type: Grant
    Filed: November 20, 2015
    Date of Patent: March 7, 2017
    Assignee: CATHOLIC UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION
    Inventors: Mi-La Cho, Hyang-Suk Rhim, Seon-Yeong Lee, Yeong-Mi Mun, Hye-Jin Son, Eun-Ji Yang, Eun-Kyung Kim
  • Publication number: 20160114007
    Abstract: The present invention relates to a composition for preventing or treating an autoimmune disease comprising, as an active ingredient, PINK1 protein or polynucleotide encoding the same. The PINK1 protein according to the present invention inhibits the activity of Th17, promotes the activity of a regulatory T cell (Treg), and increases autophagy in Treg cells, thereby controlling excessive immune responses. Therefore, the PINK1 protein can be effectively used as a pharmaceutical composition or an immunosuppressant, which is capable of preventing or treating an autoimmune disease, such as arthritis, and the like, caused by dysregulation of various kinds of immune responses.
    Type: Application
    Filed: November 20, 2015
    Publication date: April 28, 2016
    Inventors: Mi-La Cho, Hyang-Suk Rhim, Seon-Yeong Lee, Yeong-Mi Mun, Hye-Jin Son, Eun-Ji Yang, Eun-Kyung Kim
  • Publication number: 20150297676
    Abstract: The present invention relates to a composition comprising GRIM-19 protein as an active ingredient for preventing or treating obesity or lipid-related metabolic diseases. More particularly, the present invention relates to a composition for preventing or treating obesity or lipid-related metabolic diseases wherein the composition comprises GRIM-19 protein as an active ingredient for preventing or treating metabolic diseases caused by immune response disorders or interactions between genetic, metabolic, or environmental complex factors. The GRIM-19 protein according to the present invention exhibits excellent effectiveness not only in reducing lipocytes and total cholesterol content in the body, but also in suppressing the differentiation of cytotoxic Th17 cells that produce and secrete inflammatory cytokines. Also, GRIM-19 has been found to have excellent effectiveness in regulating a STAT3 mediated inflammatory response in an inflammatory environment related to obesity.
    Type: Application
    Filed: September 2, 2013
    Publication date: October 22, 2015
    Applicant: Catholic University Industry Academic Cooperation Foundation
    Inventors: Mi-La CHO, Joo-Yeon Jhun, Seon-Yeong Lee, Yeong-Mi Mun, Jun-Geol Ryu, Jae-Kyeong Byun, Hye-Jin Son, Eun-Kyung Kim, Eun-Ji Yang, Jeong-Hee Jeong