Patents by Inventor Yesim Gokmen-Polar

Yesim Gokmen-Polar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEM AND METHOD FOR DETECTING RECURRENCE OF A DISEASE
    Publication number: 20230317293
    Abstract: A method for determining a recurrence of a disease in a patient is presented. The method includes generating a plurality of medical images of an organ of the patient and determining a plurality of recurrence probabilities from the plurality of medical images. A recurrence of the disease is determined based on the plurality of recurrence probabilities and clinicopathological data of the patient using a Bayesian network.
    Type: Application
    Filed: March 31, 2022
    Publication date: October 5, 2023
    Inventors: Sanghee Cho, Zhanpan Zhang, Soumya Ghose, Fiona Ginty, Cynthia Elizabeth Landberg Davis, Jhimli Mitra, Sunil S. Badve, Yesim Gokmen-Polar
  • SYSTEM AND METHOD FOR DETECTING RECURRENCE OF A DISEASE
    Publication number: 20230309836
    Abstract: A method for determining a recurrence of a disease in a patient is presented. The method includes generating a plurality of medical images of an organ of the patient and determining a plurality of recurrence probabilities from the plurality of medical images. A recurrence of the disease is determined based on the plurality of recurrence probabilities and clinicopathological data of the patient using a Bayesian network.
    Type: Application
    Filed: November 7, 2022
    Publication date: October 5, 2023
    Applicant: The Trustees of Indiana University
    Inventors: Souyma Ghose, Zhanpan Zhang, Sanghee Cho, Fiona Ginty, Cynthia Elizabeth Landberg Davis, Jhimli Mitra, Sunil S. Badve, Yesim Gokmen-Polar, Elizabeth Mary McDonough
  • SYSTEM AND METHOD FOR DETECTING RECURRENCE OF A DISEASE
    Publication number: 20230307137
    Abstract: A method for determining a recurrence of a disease in a patient includes generating a medical image of an organ of the patient and then extracting an invasive edge around an area of interest in the medical image. A plurality of radiomics features is obtained from the invasive edge and the recurrence of the disease is determined based on the plurality of radiomics features.
    Type: Application
    Filed: March 25, 2022
    Publication date: September 28, 2023
    Inventors: Soumya Ghose, Fiona Ginty, Cynthia Elizabeth Landberg Davis, Sanghee Cho, Sunil S. Badve, Yesim Gokmen-Polar
  • Compositions for and methods of detecting, diagnosing, and prognosing thymic cancer
    Patent number: 10233502
    Abstract: Biomarkers are provided for detecting, diagnosing and prognosing thymic cancer in individuals having or suspected of having thymic cancer. In addition, kits are provided for measuring expression levels or the presence of the biomarkers associated with thymic cancer for detecting, diagnosing and prognosing thymic cancer. Furthermore, methods are provided for detecting, diagnosing and prognosing thymic cancer in individuals having or suspected of having thymic cancer via the biomarkers.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: March 19, 2019
    Assignees: Indiana University Research and Technology Corporation, Castle Biosciences, Incorporated
    Inventors: Sunil Badve, Yesim Gokmen-Polar, Patrick J. Loehrer, Robert Cook, Derek Maetzold
  • Breast cancer prognostication and screening kits and methods of using same
    Patent number: 10174382
    Abstract: A genetic biomarker panel is provided for prognosing late onset ER+ breast cancer relapse, in a breast cancer survivor patient. Kits are also provided for measuring levels or the presence of an identified panel of genetic biomarkers. Methods are also provided for identifying a breast cancer survivor patient at a relatively high risk of suffering a breast cancer relapse within 8 years of diagnosis, and therefore suitable for treatment with an aggressive chemotherapeutic regimen. The method may also be used for identifying a breast cancer survivor patient not at high risk of suffering a breast cancer relapse within 8 years of diagnosis, and thus not suitable for treatment with an aggressive chemotherapeutic regimen. The genetic biomarker panel includes an oligonucleotide/nucleic acid sequence specific for the following genes: MKI67, SPAG5, ESPL1, PLK1, or a genetic panel for MKI67, SPAG5, ESPL1, PLK1 and PGR.
    Type: Grant
    Filed: May 13, 2015
    Date of Patent: January 8, 2019
    Assignees: University of Notre Dame, Indiana University Research and Technology Corporation
    Inventors: Steven Buechler, Sunil Badve, Yesim Gokmen-Polar
  • BREAST CANCER PROGNOSTICATION AND SCREENING KITS AND METHODS OF USING SAME
    Publication number: 20160333413
    Abstract: A genetic biomarker panel is provided for prognosing late onset ER+ breast cancer relapse, in a breast cancer survivor patient. Kits are also provided for measuring levels or the presence of an identified panel of genetic biomarkers. Methods are also provided for identifying a breast cancer survivor patient at a relatively high risk of suffering a breast cancer relapse within 8 years of diagnosis, and therefore suitable for treatment with an aggressive chemotherapeutic regimen. The method may also be used for identifying a breast cancer survivor patient not at high risk of suffering a breast cancer relapse within 8 years of diagnosis, and thus not suitable for treatment with an aggressive chemotherapeutic regimen. The genetic biomarker panel includes an oligonucleotide/nucleic acid sequence specific for the following genes: MKI67, SPAG5, ESPL1, PLK1, or a genetic panel for MKI67, SPAG5, ESPL1, PLK1 and PGR.
    Type: Application
    Filed: May 13, 2015
    Publication date: November 17, 2016
    Applicants: University of Notre Dame, Indiana University School of Medicine
    Inventors: Steven Buechler, Sunil Badve, Yesim Gokmen-Polar
  • Compositions for and Methods of Detecting, Diagnosing, and Prognosing Thymic Cancer
    Publication number: 20140371081
    Abstract: Biomarkers are provided for detecting, diagnosing and prognosing thymic cancer in individuals having or suspected of having thymic cancer. In addition, kits are provided for measuring expression levels or the presence of the biomarkers associated with thymic cancer for detecting, diagnosing and prognosing thymic cancer. Furthermore, methods are provided for detecting, diagnosing and prognosing thymic cancer in individuals having or suspected of having thymic cancer via the biomarkers.
    Type: Application
    Filed: June 22, 2013
    Publication date: December 18, 2014
    Applicants: Indiana University Research and Technology Corporation, Castle Biosciences Incorporated
    Inventors: Sunil Badve, Yesim Gokmen-Polar, Patrick J. Loehrer, Robert Cook, Derek Maetzold