Patents by Inventor Yevgeni Besidski

Yevgeni Besidski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Triazole compounds and their use as gamma secretase modulators
    Patent number: 9718805
    Abstract: The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. The invention also relates to pharmaceutical compositions comprising these compounds, to processes for making these compounds, and to their use as medicaments for treatment and/or prevention of A?-related diseases.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: August 1, 2017
    Assignee: Acturum Life Science AB
    Inventors: Yevgeni Besidski, Ulrika Yngve, Kim Paulsen, Christian Erik Linde, Jonas Malmborg
  • Triazole compounds and their use as gamma secretase modulators
    Patent number: 9611254
    Abstract: The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. The invention also relates to pharmaceutical compositions comprising these compounds, to processes for making these compounds, and to their use as medicaments for treatment and/or prevention of A?-related diseases.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: April 4, 2017
    Assignee: Acturum Life Science AB
    Inventors: Yevgeni Besidski, Ulrika Yngve, Kim Paulsen, Christian Erik Linde, Gunnar Nordvall, Istvan Macsari, Jonas Malmborg
  • Pyrimidine compounds and their use as gamma secretase modulators
    Patent number: 9439904
    Abstract: The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. The invention also relates to pharmaceutical compositions comprising these compounds, to processes for making these compounds, and to their use as medicaments for treatment and/or prevention of A?-related diseases.
    Type: Grant
    Filed: June 3, 2014
    Date of Patent: September 13, 2016
    Assignee: Acturum Life Science AB
    Inventors: Yevgeni Besidski, Ulrika Yngve, Kim Paulsen, Christian Erik Linde, Istvan Macsari, Jonas Malmborg, Alexander Paptchikhine, Per Arvidsson
  • PYRIMIDINE COMPOUNDS AND THEIR USE AS GAMMA SECRETASE MODULATORS
    Publication number: 20160129002
    Abstract: The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. The invention also relates to pharmaceutical compositions comprising these compounds, to processes for making these compounds, and to their use as medicaments for treatment and/or prevention of A?-related diseases.
    Type: Application
    Filed: June 3, 2014
    Publication date: May 12, 2016
    Applicant: Acturum Life Science AB
    Inventors: Yevgeni BESIDSKI, Ulrika YNGVE, Kim PAULSEN, Christian Erik LINDE, Istvan MACSARI, Jonas MALMBORG, Alexander PAPTCHIKHINE, Per ARVIDSSON
  • TRIAZOLE COMPOUNDS AND THEIR USE AS GAMMA SECRETASE MODULATORS
    Publication number: 20160122326
    Abstract: The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. The invention also relates to pharmaceutical compositions comprising these compounds, to processes for making these compounds, and to their use as medicaments for treatment and/or prevention of A?-related diseases.
    Type: Application
    Filed: June 3, 2014
    Publication date: May 5, 2016
    Inventors: Yevgeni BESIDSKI, Ulrika YNGVE, Kim PAULSEN, Christian LINDE, Gunnar NORDVALL, Istvan MACSARI, Jonas MALMBORG
  • TRIAZOLE COMPOUNDS AND THEIR USE AS GAMMA SECRETASE MODULATORS
    Publication number: 20160108022
    Abstract: The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts thereof. The invention also relates to pharmaceutical compositions comprising these compounds, to processes for making these compounds, and to their use as medicaments for treatment and/or prevention of A?-related diseases.
    Type: Application
    Filed: June 3, 2014
    Publication date: April 21, 2016
    Inventors: Yevgeni BESIDSKI, Ulrika YNGVE, Kim PAULSEN, Christian Erik LINDE, Jonas MALMBORG
  • Compounds
    Patent number: 8168668
    Abstract: The present invention relates to new compounds or salts, solvates or solvated salts thereof, processes for their preparation and to new intermediates used in the preparation thereof, pharmaceutical compositions containing said compounds and to the use of said compounds in therapy.
    Type: Grant
    Filed: October 14, 2009
    Date of Patent: May 1, 2012
    Assignee: AstraZeneca AB
    Inventors: Yevgeni Besidski, Martin Nylof, Inger Kers, Karin Skogholm, Shawn Johnstone, Paul Jones, Denis Labrecque, Andrew Griffin
  • N-(8-heteroaryltetrahydronaphtalene-2yl) or N-(5-heteroarylchromane-3-yl) carboxamide derivatives for the treatment of pain
    Patent number: 8143408
    Abstract: The present invention relates to new compounds of formula (I) and to pharmaceutical composition containing said compounds and to the use of said compounds in therapy. The present invention further relates to processes for the preparation of said compounds and to new intermediates useful in the preparation thereof.
    Type: Grant
    Filed: April 22, 2008
    Date of Patent: March 27, 2012
    Assignee: AstraZeneca AB
    Inventors: Yevgeni Besidski, Inger Kers, Martin Nylöf, Lars Sandberg, Karin Skogholm
  • New Compounds
    Publication number: 20100286202
    Abstract: The present invention relates to new compounds or salts, solvates or solvated salts thereof, processes for their preparation and to new intermediates used in the preparation thereof, pharmaceutical compositions containing said compounds and to the use of said compounds in therapy.
    Type: Application
    Filed: October 14, 2009
    Publication date: November 11, 2010
    Applicant: AstraZeneca AB
    Inventors: Yevgeni Besidski, Martin Nylöf, Inger Kers, Karin Skogholm, Shawn Johnstone, Paul Jones, Denis Labrecque, Andrew Griffin
  • NOVEL N-(8-HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N-(5-HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN
    Publication number: 20100137322
    Abstract: The present invention relates to new compounds of formula (I) and to pharmaceutical composition containing said compounds and to the use of said compounds in therapy. The present invention further relates to processes for the preparation of said compounds and to new intermediates useful in the preparation thereof.
    Type: Application
    Filed: April 22, 2008
    Publication date: June 3, 2010
    Applicant: ASTRAZENECA AB
    Inventors: Yevgeni Besidski, Inger Kers, Martin Nylof, Lars Sandberg, Karin Skogholm
  • Benzimidazole derivatives
    Patent number: 7645784
    Abstract: Compounds of formula I, wherein R1, m, R2, R3, p, n, R5 and R9 are as defined as in the specification, salts, solvates or solvated salts thereof, processes for their preparation, intermediates used in the preparation thereof, pharmaceutical formulations containing said compounds and the use of said compounds in therapy.
    Type: Grant
    Filed: May 13, 2004
    Date of Patent: January 12, 2010
    Assignee: AstraZeneca AB
    Inventors: Yevgeni Besidski, Inger Kers, Martin Nylöf, Didier Rotticci, Andis Slaitas, Mats Svensson
  • 3-Oxoisoindoline-1-Carboxamide Derivatives as Analgesic Agents
    Publication number: 20090291983
    Abstract: Compounds of formula I wherein R1, R2, R3, R4, R5 and R6 are as described in the specification, pharmaceutically acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: July 12, 2007
    Publication date: November 26, 2009
    Applicant: AstraZeneca AB
    Inventors: Yevgeni Besidski, Ylva Gravenfors, Inger Kers, Karin Skogholm, Mats Svensson
  • Compounds
    Patent number: 7618993
    Abstract: The present invention relates to new compounds or salts, solvates or solvated salts thereof, processes for their preparation and to new intermediates used in the preparation thereof, pharmaceutical compositions containing said compounds and to the use of said compounds in therapy.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: November 17, 2009
    Assignee: AstraZeneca AB
    Inventors: Yevgeni Besidski, Martin Nylöf, Inger Kers, Karin Skogholm, Shawn Johnstone, Paul Jones, Denis Labrecque, Andrew Griffin
  • Compounds
    Publication number: 20080171770
    Abstract: The present invention relates to new compounds or salts, solvates or solvated salts thereof, processes for their preparation and to new intermediates used in the preparation thereof, pharmaceutical compositions containing said compounds and to the use of said compounds in therapy.
    Type: Application
    Filed: December 21, 2006
    Publication date: July 17, 2008
    Applicant: AstraZeneca AB
    Inventors: Yevgeni Besidski, Martin Nylof, Inger Kers, Karin Skogholm, Shawn Johnston, Paul Jones, Denis Lebrecque, Andrew Griffin
  • Hydroxymethylbenzothiazoles Amides
    Publication number: 20080070946
    Abstract: The present invention relates to new compounds, or salts, solvates or solvated salts thereof, processes for their preparation and to new intermediates used in the preparation thereof, pharmaceutical compositions containing said compounds and to the use of said compounds in therapy.
    Type: Application
    Filed: October 5, 2005
    Publication date: March 20, 2008
    Applicant: AstraZeneca AB
    Inventors: Yevgeni Besidski, William Brown, Magali Harter, Yin Hu, Shawn Johnstone, Paul Jones, Denis Labrecque, Alexander Munro, Christopher Walpole
  • New Heterocyclic Amides
    Publication number: 20080015222
    Abstract: The present invention relates to new compounds or salts, solvates or solvated salts thereof, processes for their preparation and to new intermediates used in the preparation thereof, pharmaceutical compositions containing said compounds and to the use of said compounds in therapy.
    Type: Application
    Filed: September 19, 2005
    Publication date: January 17, 2008
    Applicant: ASTRAZENECA AB
    Inventors: Yevgeni Besidski, Inger Kers, Martin Nylof, Andis Slaitas
  • New benzimidazole derivatives
    Publication number: 20060287377
    Abstract: Compounds of formula I, wherein R1, m, R2, R3, p, n, R5 and R9 are as defined as in the specification, salts, solvates or solvated salts thereof, processes for their preparation, intermediates used in the preparation thereof, pharmaceutical formulations containing said compounds and the use of said compounds in therapy.
    Type: Application
    Filed: May 13, 2004
    Publication date: December 21, 2006
    Inventors: Yevgeni Besidski, Inger Kers, Martin Nylof, Didier Rotticci, Andis Slaitas, Mats Svensson
  • Heterocyclic amides exhibiting and inhibitory activity at the vanilloid receptor 1(vr1)
    Publication number: 20060223868
    Abstract: Compounds of formula I, wherein R1, n, R3, R4, R7, R8 and P are as defined in the specification, salts, solvates or solvated salts thereof, processes for their preparation, new intermediates used in the preparation thereof, pharmaceutical compositions containing said compounds and the use of said compounds in therapy.
    Type: Application
    Filed: April 26, 2004
    Publication date: October 5, 2006
    Applicant: AstraZeneca AB
    Inventors: Yevgeni Besidski, William Brown, Shawn Johnstone, Denis Labrecque, Alexander Munro, Didier Rotticci, Christopher Walpole, Ronald Zemribo, Andreas Petersson