Patents by Inventor Yevgeny Brudno

Yevgeny Brudno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR DRUG DELIVERY
    Publication number: 20230390403
    Abstract: Disclosed herein are methods for drug delivery, as well as kits for drug delivery.
    Type: Application
    Filed: October 14, 2021
    Publication date: December 7, 2023
    Inventors: Yevgeny Brudno, Sharda Pandit, Sandeep Palvai, Tiffany Ferrell, Joshua G. Pierce, Nicholas Massaro, Chris Moody
  • ENHANCED VIRAL TRANSDUCTION OF MAMMALIAN CELLS USING MATERIAL SCAFFOLDS
    Publication number: 20230136350
    Abstract: Disclosed are compositions and methods for a low cost, tunable, macroporous, alginate scaffold that transduces T cells with vectors under static condition.
    Type: Application
    Filed: April 12, 2021
    Publication date: May 4, 2023
    Inventors: Yevgeny Brudno, Pritha Agarwalla, Gianpietro Dotti
  • REFILLABLE DRUG DELIVERY DEVICES AND METHODS OF USE THEREOF
    Publication number: 20220401562
    Abstract: The present invention provides refillable drug delivery systems, as well as methods of refilling the systems, and methods of using them to treat diseases.
    Type: Application
    Filed: January 6, 2022
    Publication date: December 22, 2022
    Inventors: Yevgeny Brudno, Cathal J. Kearney, Eduardo Alexandre Barros E Silva, Michael Aizenberg, Brian Kwee, Rajiv Desai, Neel Satish Joshi, David J. Mooney
  • IN SITU RECRUITMENT, REPROGRAMMING, AND RELEASE OF CAR-T CELLS
    Publication number: 20220354972
    Abstract: Disclosed are hydrogel matrixes for use in recruitment and reprogramming of CAR T cells, CAR NK cells, CAR NK T cells, CAR macrophage, Tumor infiltrating NK cells, tumor infiltrating lymphocytes, and marrow infiltrating lymphocytes.
    Type: Application
    Filed: June 18, 2020
    Publication date: November 10, 2022
    Inventors: Yevgeny BRUDNO, Gianpietro DOTTI, Pritha AGARWALLA
  • COMPOSITIONS AND METHODS FOR DRUG DELIVERY
    Publication number: 20210353767
    Abstract: Disclosed herein are methods for drug delivery, as well as kits for drug delivery.
    Type: Application
    Filed: September 30, 2019
    Publication date: November 18, 2021
    Inventors: Yevgeny BRUDNO, Mary R. Adams
  • REFILLABLE DRUG DELIVERY DEVICES AND METHODS OF USE THEREOF
    Publication number: 20200197526
    Abstract: The present invention provides refillable drug delivery systems, as well as methods of refilling the systems, and methods of using them to treat diseases.
    Type: Application
    Filed: December 6, 2019
    Publication date: June 25, 2020
    Inventors: Yevgeny Brudno, Cathal J. Kearney, Eduardo Alexandre Barros E Silva, Michael Aizenberg, Brian Kwee, Rajiv Desai, Neel Satish Joshi, David J. Mooney
  • REFILLABLE DRUG DELIVERY DEVICES AND METHODS OF USE THEREOF
    Publication number: 20170119892
    Abstract: The present invention provides refillable drug delivery devices. The invention is based in part on the development of systemically administered drug payloads that home to and refill resident, e.g., previously administered/implanted, drug delivery systems, e.g., hydrogel drug delivery systems. In one aspect, the drug delivery depots of the invention are systemically administered, e.g., enterally administered or parenterally administered. The invention provides a method of nanotherapeutic drug delivery, e.g., a DNA nanotechnology-based approach for blood-based drug refilling of intra-tumor drug depots.
    Type: Application
    Filed: April 6, 2015
    Publication date: May 4, 2017
    Inventors: Yevgeny Brudno, Cathal J. Kearney, Eduardo Silva, Michael Aizenberg, Brian Kwee, Rajiv Desai, Neel S. Joshi, David J. Mooney
  • REFILLABLE DRUG DELIVERY DEVICES AND METHODS OF USE THEREOF
    Publication number: 20160220686
    Abstract: The present invention provides refillable drug delivery systems, as well as methods of refilling the systems, and methods of using them to treat diseases.
    Type: Application
    Filed: April 12, 2016
    Publication date: August 4, 2016
    Inventors: Yevgeny Brudno, Cathal J. Kearney, Eduardo Silva, Michael Aizenberg, Brian Kwee, Rajiv Desai, Neel S. Joshi, David J. Mooney
  • REFILLABLE DRUG DELIVERY DEVICES AND METHODS OF USE THEREOF
    Publication number: 20160114046
    Abstract: The present invention provides refillable drug delivery systems, as well as methods of refilling the systems, and methods of using them to treat diseases.
    Type: Application
    Filed: October 8, 2015
    Publication date: April 28, 2016
    Inventors: Yevgeny Brudno, Cathal J. Kearney, Eduardo Silva, Michael Aizenberg, Brian Kwee, Rajiv Desai, Neel S. Joshi, David J. Mooney
  • Polymer evolution via templated synthesis
    Publication number: 20090203530
    Abstract: The invention provides a method for producing polymers having a desirable property, for example, catalytic activity or binding activity, via evolutionary nucleic acid-mediated chemistry.
    Type: Application
    Filed: June 7, 2006
    Publication date: August 13, 2009
    Inventors: David R. Liu, Daniel M. Rosenbaum, Yevgeny Brudno