Patents by Inventor Yewei Sun

Yewei Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8796281
    Abstract: The present invention provides pyrazine derivatives of formula I and pharmaceutically acceptable salts thereof, wherein the designation of R1, R2, R3 and R4 is provided herein. The invention also provides syntheses for preparation of such compounds. The invention further provides methods of use of these compounds and pharmaceutical compositions containing them for treatment and/or prevention of diseases and for manufacture of medicaments. These compounds and pharmaceutical compositions have antioxidative and thrombolytic effects, and thus can be used for the treatment and/or prevention of cerebral stroke caused by ischemia, and used for manufacture of medicaments for the treatment and/or prevention of nervous system diseases caused by excessive amount of radicals and/or thrombosis, infectious diseases, metabolic system diseases, cardiovascular and cerebrovascular diseases, and age-related degenerative diseases.
    Type: Grant
    Filed: July 1, 2011
    Date of Patent: August 5, 2014
    Assignee: Jinan University
    Inventors: Yuqiang Wang, Yewei Sun, Pei Yu, Jing Du, Gaoxiao Zhang
  • Patent number: 8404688
    Abstract: The present invention provides novel nitrones, their preparation and use. The novel compounds have the following formula: I The compounds of the present invention have strong antioxidative activity, and are thrombolytic. These compounds can be used to treat and/or prevent diseases caused by overproduction of free radicals and/or formation of thrombus.
    Type: Grant
    Filed: April 16, 2009
    Date of Patent: March 26, 2013
    Assignee: Jinan University
    Inventors: Yuqiang Wang, Jie Jiang, Pei Yu, Yewei Sun, Linda Wang, Zaijun Zhang
  • Publication number: 20120115874
    Abstract: The present invention provides pyrazine derivatives of formula I and pharmaceutically acceptable salts thereof, wherein the designation of R1, R2, R3 and R4 is provided herein. The invention also provides syntheses for preparation of such compounds. The invention further provides methods of use of these compounds and pharmaceutical compositions containing them for treatment and/or prevention of diseases and for manufacture of medicaments. These compounds and pharmaceutical compositions have antioxidative and thrombolytic effects, and thus can be used for the treatment and/or prevention of cerebral stroke caused by ischemia, and used for manufacture of medicaments for the treatment and/or prevention of nervous system diseases caused by excessive amount of radicals and/or thrombosis, infectious diseases, metabolic system diseases, cardiovascular and cerebrovascular diseases, and age-related degenerative diseases.
    Type: Application
    Filed: July 1, 2011
    Publication date: May 10, 2012
    Applicant: Jinan University
    Inventors: Yuqiang Wang, Yewei Sun, Pei Yu, Jing Du, Gaoxiao Zhang
  • Publication number: 20110034485
    Abstract: The present invention provides novel nitrones, their preparation and use. The novel compounds have the following formula: I The compounds of the present invention have strong antioxidative activity, and are thrombolytic. These compounds can be used to treat and/or prevent diseases caused by overproduction of free radicals and/or formation of thrombus.
    Type: Application
    Filed: April 16, 2009
    Publication date: February 10, 2011
    Inventors: Yuqiang Wang, Jie Jiang, Pei Yu, Yewei Sun, Linda Wang, Zaijun Zhang