Patents by Inventor Yi Ba
Yi Ba has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11939679Abstract: The invention discloses a method for preparing an anticorrosive surface layer of a metal material in a marine environment by laser, which belongs to the technical field of laser processing. First, the laser cladding method is used to prepare a cladding surface layer on the surface of the metal material that is not easy to undergo chemical substitution reaction with the chlorides (NaCl, MgCl2 , CaCl2 etc.) in the seawater. Then, on the surface of the cladding surface layer, ultrafast laser processing is used to form a surface layer with a wetting angle (and water) greater than 90 degrees and with hydrophobic characteristics.Type: GrantFiled: August 12, 2020Date of Patent: March 26, 2024Assignee: GUANGDONG OCEAN UNIVERSITYInventors: Wenqing Shi, Fenju An, Jiang Huang, Yuping Xie, Zhanxia Wu, Zhigang Liang, Jinming Zhan, Jinyu Huang, Yi Ba
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Publication number: 20220402581Abstract: The invention discloses a method for preparing an anticorrosive surface layer of a metal material in a marine environment by laser, which belongs to the technical field of laser processing. First, the laser cladding method is used to prepare a cladding surface layer on the surface of the metal material that is not easy to undergo chemical substitution reaction with the chlorides (NaCl, MgCl2 , CaCl2 etc.) in the seawater. Then, on the surface of the cladding surface layer, ultrafast laser processing is used to form a surface layer with a wetting angle (and water) greater than 90 degrees and with hydrophobic characteristics. The anti-corrosion surface layer obtained by the invention has hydrophobic properties, the high humidity and high salt water vapor and marine organisms in the marine environment are not easy to adhere, and the anti-corrosion surface layer is stable in salt water resistance, and is not easy to undergo chemical substitution reaction with chlorides in seawater (NaCl, MgCl2 , CaCl2 etc.Type: ApplicationFiled: August 12, 2020Publication date: December 22, 2022Inventors: Wenging Shi, Fenju An, Jiang Huang, Yuping Xie, Zhanxia Wu, Zhigang Liang, Jinming Zhan, Jinyu Huang, Yi Ba
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Patent number: 10774386Abstract: Provided are non-small cell lung cancer markers and the use thereof in diagnosing and monitoring diseases in vitro. The non-small cell lung cancer markers include at least one of 26 selected detectable mature microRNAs existing stably in human serum or plasma. Also provided are probe combinations, a kit and a biochip for detecting the non-small cell lung cancer markers. The invention further provides a method for detecting the said lung cancer markers. The method in the present invention enables extensive detection spectrum, high sensitivity, low cost, convenient sample taking and preservation. The method can be applied in the general survey of disease, solves problems of low specificity and sensitivity encountered with previous single markers, and increases significantly the clinical detection rate of diseases. The methods provide an effective means for diagnosing diseases at an early stage.Type: GrantFiled: July 11, 2016Date of Patent: September 15, 2020Assignee: MICROMEDMARK BIOTECH CO., LTD.Inventors: Chenyu Zhang, Ke Zeng, Junfeng Zhang, Yi Ba, Xi Chen, Haijin Li
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Patent number: 10077477Abstract: This invention provides a combination of microRNAs for evaluating the physiological and/or pathological condition of a subject, wherein the combination comprises all detectable microRNAs stably existing in the serum/plasma of a subject; and a method for evaluating the physiological and/or pathological condition of a subject, wherein the method includes determining all detectable microRNAs stably existing in the serum/plasma of a subject; and a kit for evaluating the physiological and/or pathological condition of a subject, wherein the kit contains the tools for determining all detectable microRNAs that stably existing in the serum/plasma of a subject; and a biochip for evaluating the physiological and/or pathological condition of a subject, wherein the biochip contains the components for determining all detectable microRNAs stably existing in the serum/plasma of a subject.Type: GrantFiled: December 30, 2013Date of Patent: September 18, 2018Assignee: JIANGSU MINGMA BIOTECH CO., LTD.Inventors: Chenyu Zhang, Junfeng Zhang, Xi Chen, Yi Ba, Jiangning Chen, Jin Wang, Ke Zeng, Hongjie Zhang
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Patent number: 10011880Abstract: MicroRNAs are provided for evaluating the physiological and/or pathological condition of a subject; and a kit thereof is provided for evaluating the physiological and/or pathological condition of a subject, wherein the kit contains the tools for determining all detectable microRNAs that stably existing in the serum/plasma of a subject; and a biochip for evaluating the physiological and/or pathological condition of a subject, wherein the biochip contains the components for determining all detectable microRNAs stably existing in the serum/plasma of a subject. The aforementioned combination, method, kit and biochip can be used for diagnosis as well as differentially diagnosis of diseases including various tumors.Type: GrantFiled: June 2, 2016Date of Patent: July 3, 2018Assignee: JIANGSU MINGMA BIOTECH CO., LTD.Inventors: Chenyu Zhang, Junfeng Zhang, Xi Chen, Yi Ba, Jiangning Chen, Jin Wang, Ke Zeng, Hongjie Zhang
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Publication number: 20160312310Abstract: Provided are non-small cell lung cancer markers and the use thereof in diagnosing and monitoring diseases in vitro. The non-small cell lung cancer markers include at least one of 26 selected detectable mature microRNAs existing stably in human serum or plasma. Also provided are probe combinations, a kit and a biochip for detecting the non-small cell lung cancer markers. The invention further provides a method for detecting the said lung cancer markers. The method in the present invention enables extensive detection spectrum, high sensitivity, low cost, convenient sample taking and preservation. The method can be applied in the general survey of disease, solves problems of low specificity and sensitivity encountered with previous single markers, and increases significantly the clinical detection rate of diseases. The methods provide an effective means for diagnosing diseases at an early stage.Type: ApplicationFiled: July 11, 2016Publication date: October 27, 2016Inventors: Chenyu Zhang, Ke Zeng, Junfeng Zhang, Yi Ba, Xi Chen, Haijin Li
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Publication number: 20160273054Abstract: This invention provides a combination of microRNAs for evaluating the physiological and/or pathological condition of a subject, wherein the combination comprises all detectable microRNAs stably existing in the serum/plasma of a subject; and a method for evaluating the physiological and/or pathological condition of a subject, wherein the method includes determining all detectable microRNAs stably existing in the serum/plasma of a subject; and a kit for evaluating the physiological and/or pathological condition of a subject, wherein the kit contains the tools for determining all detectable microRNAs that stably existing in the serum/plasma of a subject; and a biochip for evaluating the physiological and/or pathological condition of a subject, wherein the biochip contains the components for determining all detectable microRNAs stably existing in the serum/plasma of a subject.Type: ApplicationFiled: June 2, 2016Publication date: September 22, 2016Inventors: Chenyu ZHANG, Junfeng ZHANG, Xi CHEN, Yi BA, Jiangning CHEN, Jin WANG, Ke ZENG, Hongjie ZHANG
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Patent number: 9388470Abstract: The present invention provides non-small cell lung cancer markers and the use thereof in diagnosing and monitoring diseases in vitro. The non-small cell lung cancer markers include at least one of the 26 selected detectable mature microRNAs existing stably in human serum or plasma. The invention also provides probe combinations, a kit and biochip for detecting the non-small cell lung cancer markers. The invention further provides a method for detecting the said lung cancer markers. The method in the present invention enables extensive detection spectrum, high sensitivity, low cost, convenient sample taking and preservation. The method can be applied in the general survey of disease, solves problems of the low specificity and sensitivity encountered with previous single markers, and increases significantly the clinical detection rate of diseases; it forms an effective means for diagnosing diseases at an early stage.Type: GrantFiled: December 14, 2009Date of Patent: July 12, 2016Assignee: MICROMEDMARK BIOTECH CO., LTD.Inventors: Chenyu Zhang, Ke Zeng, Junfeng Zhang, Yi Ba, Xi Chen, Haijin Li
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Publication number: 20140121133Abstract: This invention provides a combination of microRNAs for evaluating the physiological and/or pathological condition of a subject, wherein the combination comprises all detectable microRNAs stably existing in the serum/plasma of a subject; and a method for evaluating the physiological and/or pathological condition of a subject, wherein the method includes determining all detectable microRNAs stably existing in the serum/plasma of a subject; and a kit for evaluating the physiological and/or pathological condition of a subject, wherein the kit contains the tools for determining all detectable microRNAs that stably existing in the serum/plasma of a subject; and a biochip for evaluating the physiological and/or pathological condition of a subject, wherein the biochip contains the components for determining all detectable microRNAs stably existing in the serum/plasma of a subject.Type: ApplicationFiled: December 30, 2013Publication date: May 1, 2014Applicant: JIANGSU MINGMA BIOTECH CO., LTD.Inventors: CHENYU ZHANG, JUNFENG ZHANG, XI CHEN, YI BA, JIANGNING CHEN, JIN WANG, KE ZENG, HONGJIE ZHANG
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Publication number: 20130072393Abstract: The present invention provides microRNAs for assessing the status of pancreatic cancer in a subject, and provides methods, kits, and biochips for detecting said microRNAs.Type: ApplicationFiled: December 24, 2009Publication date: March 21, 2013Applicant: MICROMEDMARK BIOTECH CO., LTD.Inventors: Chenyu Zhang, Rui Liu, Cheng Wang, Yi Ba, Chunni Zhang, Ke Zeng
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Publication number: 20110117565Abstract: The present invention provides non-small cell lung cancer markers and the use thereof. The non-small cell lung cancer markers in the present invention include at least one of the 26 selected detectable mature microRNAs existing stably in human serum or plasma. The invention also provides a probe combination, kit and biochip for detecting the non-small cell lung cancer markers. The invention further provides a method for detecting microRNAs in the serum of lung cancer patients. By detecting the variations of microRNAs in the serum of lung cancer patients, the disease can be diagnosed in vitro; the progression course of the disease can be predicted; the occurrence of complications, the rate of relapse and the prognosis of the disease can be monitored; the drug efficacy and therapeutic effects can be analyzed. The method in the present invention enables extensive detection spectrum, high sensitivity, low cost, convenient sample taking and preservation.Type: ApplicationFiled: December 14, 2009Publication date: May 19, 2011Applicant: Micromedmark Biotech Co., Ltd.Inventors: Chenyu Zhang, Ke Zeng, Junfeng Zhang, Yi Ba, Xi Chen, Haijin Li
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Publication number: 20100173288Abstract: This invention provides a combination of microRNAs for evaluating the physiological and/or pathological condition of a subject, wherein the combination comprises all detectable microRNAs stably existing in the serum/plasma of a subject; and a method for evaluating the physiological and/or pathological condition of a subject, wherein the method includes determining all detectable microRNAs stably existing in the serum/plasma of a subject; and a kit for evaluating the physiological and/or pathological condition of a subject, wherein the kit contains the tools for determining all detectable microRNAs that stably existing in the serum/plasma of a subject; and a biochip for evaluating the physiological and/or pathological condition of a subject, wherein the biochip contains the components for determining all detectable microRNAs stably existing in the serum/plasma of a subject.Type: ApplicationFiled: December 6, 2007Publication date: July 8, 2010Inventors: Chenyu Zhang, Junfeng Zhang, Xi Chen, Yi Ba, Jiangning Chen, Jin Wang, Ke Zeng, Hongjie Zhang