Patents by Inventor Yi-Chen Chia

Yi-Chen Chia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HCD formulation for cancer treatment
    Patent number: 9682063
    Abstract: The present invention provides a novel formulation for cancer treatment and a method for enhancing the HCD's efficacy in cancer treatment. Specifically, the present invention provides copper-modified silica nanoparticles loaded with HCD, which exhibits better efficacy than some conventional anticancer drugs.
    Type: Grant
    Filed: February 25, 2015
    Date of Patent: June 20, 2017
    Assignee: National Dong Hwa University
    Inventors: Ching-Feng Weng, Yi-Chen Chia, Chia-Hung Lee, T. Varadharajan
  • HCD FORMULATION FOR CANCER TREATMENT
    Publication number: 20160243236
    Abstract: The present invention provides a novel formulation for cancer treatment and a method for enhancing the HCD's efficacy in cancer treatment. Specifically, the present invention provides copper-modified silica nanoparticles loaded with HCD, which exhibits better efficacy than some conventional anticancer drugs.
    Type: Application
    Filed: February 25, 2015
    Publication date: August 25, 2016
    Inventors: Ching-Feng Weng, Yi-Chen Chia, Chia-Hung Lee, T. Varadharajan
  • Composition having A. paniculata for wound healing and skin whitening, and method by using the same
    Publication number: 20160193139
    Abstract: The present invention provides a pharmaceutical composition for wound healing and/or skin whitening. The pharmaceutical composition comprises active ingredient of Andrographis paniculata extract and/or Andrographolide and a pharmaceutical acceptable carrier. The present invention also provides a method for wound healing and/or skin whitening by using the present pharmaceutical composition. The composition and method of the present invention show better efficacy in wound healing and skin whitening than conventional drugs.
    Type: Application
    Filed: March 17, 2016
    Publication date: July 7, 2016
    Applicant: National Dong Hua University
    Inventors: CHING-FENG WENG, YI-CHEN CHIA, CHIA-JEN WU, CHIH-CHIEN TSENG
  • Method and composition for treating diabetes mellitus
    Patent number: 9226950
    Abstract: The present invention relates to a method or composition for glycemic control in a subject, which is effective for treating diabetes mellitus, comprising administering the subject with a pharmaceutical composition comprising a therapeutically effective amount of an aliphatic alcohol having a general formula of CH3(CH2)nCH2OH, wherein n is an integer from 10 to 40, such as tetracosanol, and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: November 12, 2013
    Date of Patent: January 5, 2016
    Assignee: National Dong Hwa University
    Inventors: Ching-Feng Weng, Chin-piao Chen, Yi-Chen Chia, Chia-Yu Hsu
  • METHOD AND PHARMACEUTICAL COMPOSITION FOR TREATING COLORECTAL CANCER
    Publication number: 20150366836
    Abstract: The present invention is related to a method and pharmaceutical composition for treating colorectal cancer. The pharmaceutical composition comprises an effective amount of 16-hydroxy-cleroda-3,13-dine-15,16-olide as active ingredient, and a pharmaceutically acceptable carrier. The present method and pharmaceutical composition provides good efficacy in treating colorectal cancer. The present invention also establishes an animal model, which provides a better drug screening platform for the research.
    Type: Application
    Filed: June 24, 2014
    Publication date: December 24, 2015
    Inventors: Ching-Feng Weng, Yi-Chen Chia, Jia-Huei Zheng
  • METHOD AND PHARMACEUTICAL COMPOSITION FOR TREATING LUNG CANCER
    Publication number: 20150329512
    Abstract: The present invention is related to a method and pharmaceutical composition for treating lung cancer. The pharmaceutical composition comprises an effective amount of 16-hydroxy-cleroda-3,13-dine-15,16-olide as active ingredient, and a pharmaceutically acceptable carrier. The present method and pharmaceutical composition provides good efficacy in treating lung cancer even for drug-resistance patient. The present invention also establishes an animal model bearing human lung cancer, which provides a better drug screening platform for the research.
    Type: Application
    Filed: May 16, 2014
    Publication date: November 19, 2015
    Applicant: National Dong Hua University
    Inventors: Ching-Feng Weng, Yi-Chen Chia, Wei-Jun Chiu
  • COMPOSITION HAVING A. paniculata FOR WOUND HEALING AND SKIN WHITENING, AND METHOD BY USING THE SAME
    Publication number: 20150182570
    Abstract: The present invention provides a pharmaceutical composition for wound healing and/or skin whitening. The pharmaceutical composition comprises active ingredient of Andrographis paniculata extract and/or Andrographolide and a pharmaceutical acceptable carrier. The present invention also provides a method for wound healing and/or skin whitening by using the present pharmaceutical composition. The composition and method of the present invention show better efficacy in wound healing and skin whitening than conventional drugs.
    Type: Application
    Filed: December 31, 2013
    Publication date: July 2, 2015
    Applicant: National Dong Hua University
    Inventors: CHING-FENG WENG, Yi-Chen Chia, Chia-Jen Wu, Chih-Chien Tseng
  • METHOD AND PHARMACEUTICAL COMPOSITION FOR LIVER FIBROSIS PREVENTION AND/OR TREATMENT
    Publication number: 20150147417
    Abstract: The present invention is related to a method for liver fibrosis prevention and/or treatment and a pharmaceutical composition thereof. The method and the pharmaceutical composition are made by taking the advantage of Blumea lacera ‘efficacy in accumulating lipid in hepatic stellate cells, down-regulating the proliferation of hepatic stellate cells, inhibiting the mobility of hepatic stellate cells, preventing the activation of hepatic stellate cells, and decreasing the synthesis of ECM proteins. The present invention not only provides a novel optional for clinical prevention and treatment of liver fibrosis, but also promotes the industrial value of Blumea lacera.
    Type: Application
    Filed: November 22, 2013
    Publication date: May 28, 2015
    Applicant: National Dong Hua University
    Inventors: Ching-Feng Weng, Yi-Chen Chia, Chia-Jen Wu, Hsiang-i Tsai
  • METHOD AND COMPOSITION FOR TREATING DIABETES MELLITUS
    Publication number: 20150133371
    Abstract: The present invention relates to a method or composition for glycemic control in a subject, which is effective for treating diabetes mellitus, comprising administering the subject with a pharmaceutical composition comprising a therapeutically effective amount of an aliphatic alcohol having a general formula of CH3(CH2)nCH2OH, wherein n is an integer from 10 to 40, such as tetracosanol, and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: November 12, 2013
    Publication date: May 14, 2015
    Applicant: National Dong Hwa University
    Inventors: Ching-Feng Weng, Chin-piao Chen, Yi-Chen Chia, Chia-Yu Hsu
  • Extract from the leaves of Roem., and the preparation process and uses thereof
    Patent number: 7229652
    Abstract: Disclosed are extracts from the leaves of Toona sinensis Roem. prepared by extracting the leaves of Toona sinensis Roem. using water and an alcohol in sequence. Also disclosed are processes for preparing extracts from the leaves of Toona sinensis Roem., and uses of such extracts in the manufacture of medicaments for use in the treatment of ovarian cancer and/or bladder cancer.
    Type: Grant
    Filed: February 23, 2004
    Date of Patent: June 12, 2007
    Assignee: Kaohsiung Medical University
    Inventors: Shyng-Shiou Yuan, Hseng-Kuang Hsu, Yi-Chen Chia
  • Extract from the leaves of Toona sinensis Roem., and the preparation process and uses thereof
    Publication number: 20050186297
    Abstract: Disclosed are extracts from the leaves of Toona sinensis Roem. prepared by extracting the leaves of Toona sinensis Roem. using water and an alcohol in sequence. Also disclosed are processes for preparing extracts from the leaves of Toona sinensis Roem., and uses of such extracts in the manufacture of medicaments for use in the treatment of ovarian cancer and/or bladder cancer.
    Type: Application
    Filed: February 23, 2004
    Publication date: August 25, 2005
    Inventors: Shyng-Shiou Yuan, Hseng-Kuang Hsu, Yi-Chen Chia