Abstract: A flash memory device and method of making the same are disclosed. The flash memory device is located on a substrate and includes a floating gate electrode, a tunnel dielectric layer located between the substrate and the floating gate electrode, a smaller length control gate electrode and a control gate dielectric layer located between the floating gate electrode and the smaller length control gate electrode. The length of a major axis of the smaller length control gate electrode is less than a length of a major axis of the floating gate electrode.

Abstract: Disclosed herein is a device for synthesizing ribonucleic acids (RNAs). According to embodiments of the present disclosure, the device comprises an in vitro transcription (IVT) module, a digestion module, and a processor. Optionally, the present device further comprises an IVT reaction monitoring means, a digestion reaction monitoring means, and/or a purifying means. Also disclosed herein are the methods of synthesizing RNA by use of the present device.

Abstract: The invention relates to a microfluidic device for culturing spheroids of human or animal body cells. The device can generate ample numbers (e.g., 5000) of uniform-sized spheroids, and the spheroids can be harvested for conventional biochemistry analysis (e.g. flow cytometry). In addition, the device can be used for observing the cultured samples using selective plane illumination microscopy (SPIM). In at least one embodiment, the microfluidic device incorporates a main body; a fluid channel extending inside the main body and having two inlets and an outlet open to the outside; and a plurality of chambers for culturing cell spheroids which are formed at the underneath of the fluid channel.

Abstract: A microfluidic particle separation device includes a substrate and a plurality of electrode bars formed on the substrate, disposed around as array center, angularly spaced apart from one another, and extending radially with respect to the array center so as to form a radially-extending electrode array that is capable of inducing circular or elliptical shear flow of the liquid through travelling-wave electroosmosis when being applied with a travelling-wave electric potential.

Abstract: The present disclosure relates general to devices, systems, and methods of using such devices in creating and handling hanging drops of fluid. The present disclosure also relates to cell culture devices, methods and/or systems of using such devices as well as the use of cell culture devices, for example, for research and high throughput screening.

Abstract: A measurement system for measuring a pressure of a fluid is provided. The measurement system includes a sensing module and a liquid electrical circuit. The sensing module includes a flexible film and a liquid electronic device. The flexible film has a first side and a second side opposite to the first side. The fluid is disposed on the first side of the flexible film, and the liquid electronic device is disposed on the second side of the flexible film. The flexible film converts the pressure of the fluid into a parameter of the liquid electronic device. The liquid electrical circuit is electrically coupled to the liquid electronic device. The liquid electronic device and the liquid electrical circuit output a measurement signal corresponding to the parameter in response to an applied electrical energy. A manufacture method of a measurement system is also provided.

Abstract: The present disclosure relates general to devices, systems, and methods of using such devices in creating and handling hanging drops of fluid. The present disclosure also relates to cell culture devices, methods and/or systems of using such devices as well as the use of cell culture devices, for example, for research and high throughput screening.

Abstract: The present invention relates to a microfluidic array platform comprising a substrate and two layers between which one membrane is sandwiched, wherein a plurality of cell culture wells are constructed in the top layer and one or more microfluidic channels for oxygen scavenging reactions or/and oxygen generating reactions to control the oxygen tensions are constructed in the bottom player. The microfluidic array platform is capable of simultaneously performing cell culture under different oxygen tensions and compatible with existing cell incubators and high-throughput instruments for cost-effective setup and straightforward operation.

Abstract: The present disclosure relates general to devices, systems, and methods of using such devices in creating and handling hanging drops of fluid. The present disclosure also relates to cell culture devices, methods and/or systems of using such devices as well as the use of cell culture devices, for example, for research and high throughput screening.

Abstract: A measurement system for measuring a pressure of a fluid is provided. The measurement system includes a sensing module and a liquid electrical circuit. The sensing module includes a flexible film and a liquid electronic device. The flexible film has a first side and a second side opposite to the first side. The fluid is disposed on the first side of the flexible film, and the liquid electronic device is disposed on the second side of the flexible film. The flexible film converts the pressure of the fluid into a parameter of the liquid electronic device. The liquid electrical circuit is electrically coupled to the liquid electronic device. The liquid electronic device and the liquid electrical circuit output a measurement signal corresponding to the parameter in response to an applied electrical energy. A manufacture method of a measurement system is also provided.

Abstract: The present invention relates to devices, systems and methods for measuring cell barrier function. In particular, the present invention relates to microfluidic devices for use in in vitro models of the blood-brain barrier and modeling the transport across this barrier.

Abstract: The invention relates to microfluidic devices and methods for using the same. In particular, the present invention provides a multiplexed hydraulic valve actuation device, systems utilizing the device, and methods of using such devices.

Abstract: Gas focusing flow cytometers are fabricatable employing simple and inexpensive manufacturing techniques. When such cytometers or conventional cytometers are combined with fiber optical light paths and laser diode and semiconductor photodetectors, light weight and handheld, optionally disposable devices which maintain high performance are possible.

Abstract: Gas focusing flow cytometers are fabricatable employing simple and inexpensive manufacturing techniques. When such cytometers or conventional cytometers are combined with fiber optical light paths and laser diode and semiconductor photodetectors, light weight and handheld, optionally disposable devices which maintain high performance are possible.

Abstract: Gas focusing flow cytometers are fabricatable employing simple and inexpensive manufacturing techniques. When such cytometers or conventional cytometers are combined with fiber optical light paths and laser diode and semiconductor photodetectors, light weight and handheld, optionally disposable devices which maintain high performance are possible.

Abstract: Gas focusing flow cytometers are fabricatable employing simple and inexpensive manufacturing techniques. When such cytometers or conventional cytometers are combined with fiber optical light paths and laser diode and semiconductor photodetectors, light weight and handheld, optionally disposable devices which maintain high performance are possible.