Patents by Inventor Yi-Ding Chu

Yi-Ding Chu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolation of Hepatitis B surface antigen from transformed yeast cells
    Patent number: 5462863
    Abstract: A method for recovering hepatitis B surface antigen protein from transformed yeast cells including the steps of (i) obtaining an aqueous homogenate of the yeast cells; (ii) enriching the hepatitis B surface antigen protein in the homogenate with a protein-aggregating reagent to form a precipitate which contains hepatitis B surface antigen protein; (iii) dissolving the precipitate in a buffer to form a suspension; and (iv) post-homogenizing the suspension to obtain a 10% to 50% increase in yield of the hepatitis B surface antigen protein as calculated based on a yield achieved without performing the post-homogenizing step.
    Type: Grant
    Filed: April 28, 1994
    Date of Patent: October 31, 1995
    Assignee: Development Center for Biotechnology
    Inventors: Jih-Han Hsieh, Shu-Ching Shih, Wei-Kuang Chi, Yi-Ding Chu, Ae-Ning Lin