Abstract: The present invention demonstrated a Cre-loxP based cofilin-1 transgenic animal model to address the pathophysiological role of over-expressed cofilin-1 on systemic development.

Abstract: An electronic device is provided. The electronic device includes a housing, a first antenna and a second antenna which are disposed near at least one edge of the housing inside the housing and a first distance away from each other, wherein the first antenna and second antenna are positioned different distances away from an edge vertical to the one edge, a communication circuit operatively connected to the first antenna and second antenna, at least one sensor, a processor, and a memory.

Abstract: A semiconductor device is described. An isolation region is disposed on the substrate. A plurality of channels extend through the isolation region from the substrate. The channels including an active channel and an inactive channel. A dummy fin is disposed on the isolation region and between the active channel and the inactive channel. An active gate is disposed over the active channel and the inactive channel, and contacts the isolation region. A dielectric material extends through the active gate and contacts a top of the dummy fin. The inactive channel is a closest inactive channel to the dielectric material. A long axis of the active channel extends in a first direction. A long axis of the active gate extends in a second direction. The active channel extends in a third direction from the substrate. The dielectric material is closer to the inactive channel than to the active channel.

Abstract: A display device according to one or more embodiments of the disclosure includes a pixel circuit layer including a base layer and circuit elements on the base layer; and a display layer on the pixel circuit layer. The display layer includes a first electrode on the pixel circuit layer; an insulating layer on the first electrode; a second electrode on the insulating layer; a light emitting stacked structure on the second electrode and including a first insulating layer, a second insulating layer, and a light emitting layer between the first insulating layer and the second insulating layer; and a third electrode on the light emitting stacked structure. The light emitting layer includes a two-dimensional material, is separated from the second electrode by the first insulating layer, and is separated from the third electrode by the second insulating layer.

Abstract: A Sigma Delta analog-to-digital converter (ADC) and a method for eliminating idle tones of the Sigma Delta ADC are provided. The Sigma Delta ADC includes a loop filter, a quantizer, an adder and a digital-to-analog converter (DAC). The loop filter performs filtering on a difference between an analog input signal and an analog feedback signal to generate a filtered signal. The quantizer is coupled to the loop filter, and generates a digital output signal according to the filtered signal. The adder is coupled to the quantizer, and adds a digital dithering signal to the digital output signal to generate a digital feedback signal. The DAC is coupled to the loop filter, and generates the analog feedback signal according to the digital feedback signal.

Abstract: A high voltage tolerant output circuit includes a boost circuit, a first bias circuit, and a buffer circuit. The boost circuit includes a first transistor and an output node. A first terminal of the first transistor is coupled with the output node. The first bias circuit is coupled with the output node and a control terminal of the first transistor, and for dividing the output voltage of the output node. The first bias circuit is further configured to transmit the divided output voltage to the control terminal of the first transistor. The buffer circuit is coupled with a second terminal of the first transistor, and for setting a first voltage of the second terminal of the first transistor. The output voltage is positive correlated to the first voltage, and a maximum value of the output voltage is higher than or equal to a maximum value of the first voltage.

Abstract: The present invention provides an alcohol extract of Ajuga taiwanensis Nakai ex Murata exhibits significant effects on inhibiting the senescence in human WI-38 lung fibroblasts and human dermal fibroblasts. Moreover, the alcohol extract of A. taiwanensis is able to suppress the expression of the cofilin-1, a protein involved in actin dynamics and cell morphology and found to be increased in senescent cells. Suppression effect of cell senescence by this herb extract is more efficient in mild concentration without over-inhibition of cell viability and growth.

Abstract: Disclosed is an open loop fractional frequency divider including an integer divider, a control circuit, and a phase interpolator. The integer divider processes an input clock according to the setting of a target frequency to generate a first frequency-divided clock and a second frequency-divided clock. The control circuit generates a coarse-tune control signal and a fine-tune control signal according to the setting. The phase interpolator generates an output clock according to the first frequency-divided clock, the second frequency-divided clock, and the two control signals. The two control signals are used for determining a first current, and their reversed signals are used for determining a second current. The phase interpolator controls a contribution of the first (second) frequency-divided clock to the generation of the output clock according to the first (second) frequency-divided clock, the reversed signal of the first (second) frequency-divided clock, and the first (second) current.

Abstract: Disclosed is an open loop fractional frequency divider including an integer divider, a control circuit, and a phase interpolator. The integer divider processes an input clock according to the setting of a target frequency to generate a first frequency-divided clock and a second frequency-divided clock. The control circuit generates a coarse-tune control signal and a fine-tune control signal according to the setting. The phase interpolator generates an output clock according to the first frequency-divided clock, the second frequency-divided clock, and the two control signals. The two control signals are used for determining a first current, and their reversed signals are used for determining a second current. The phase interpolator controls a contribution of the first (second) frequency-divided clock to the generation of the output clock according to the first (second) frequency-divided clock, the reversed signal of the first (second) frequency-divided clock, and the first (second) current.

Abstract: A high voltage tolerant output circuit includes a boost circuit, a first bias circuit, and a buffer circuit. The boost circuit includes a first transistor and an output node. A first terminal of the first transistor is coupled with the output node. The first bias circuit is coupled with the output node and a control terminal of the first transistor, and for dividing the output voltage of the output node. The first bias circuit is further configured to transmit the divided output voltage to the control terminal of the first transistor. The buffer circuit is coupled with a second terminal of the first transistor, and for setting a first voltage of the second terminal of the first transistor. The output voltage is positive correlated to the first voltage, and a maximum value of the output voltage is higher than or equal to a maximum value of the first voltage.

Abstract: The present invention provides an alcohol extract of Ajuga taiwanensis Nakai ex Murata exhibits significant effects on inhibiting the senescence in human WI-38 lung fibroblasts and human dermal fibroblasts. Moreover, the alcohol extract of A. taiwanensis is able to suppress the expression of the cofilin-1, a protein involved in actin dynamics and cell morphology and found to be increased in senescent cells. Suppression effect of cell senescence by this herb extract is more efficient in mild concentration without over-inhibition of cell viability and growth.

Abstract: A fluorescent fusion protein is provided. The fluorescent fusion protein of the invention comprises a first fluorescent protein with first emission wavelength, a second fluorescent protein with second excitation wavelength and second emission wavelength, and a linker peptide linking the first fusion protein and the second fusion protein, wherein the first emission wavelength overlaps the second excitation wavelength so that the second fluorescent protein exhibits the second emission wavelength after receiving energy. The fluorescent fusion protein of the invention exhibits a stronger fluorescence in the absence of bilivirdin (BV).

Abstract: The invention relates to a kit for preparation of target radiopharmaceuticals, a method of using the kit to prepare target radiopharmaceuticals and use of the target radiopharmaceuticals. The target radiopharmaceuticals comprise a radio-nuclear loading on liposome and inhibit the tumor growth and metastatic progression of head and neck cancer, lung cancer and brain cancer. The radiopharmaceuticals may be used for treating the mentioned cancers.

Abstract: The present invention is to provide a docking station applicable to a portable electronic device and having an anti-theft mechanism, which includes a positioning base having a top side concavely provided with a positioning space and a first abutting surface provided adjacent to one end of the positioning base and facing the positioning space; a sliding base movably connected to an opposite end of the positioning base and provided with a second abutting surface facing the positioning space, wherein the first and second abutting surfaces are respectively and protrudingly provided with a first plug and a second plug configured to be inserted into and thereby connected with corresponding sockets of the portable electronic device; a first fastener and a second fastener respectively provided at the sliding base and the positioning base and capable of being fastened together to prevent the sliding base from moving with respect to the positioning base.

Abstract: The invention relates to a kit for preparation of target radiopharmaceuticals, a method of using the kit to prepare target radiopharmaceuticals and use of the target radiopharmaceuticals. The target radiopharmaceuticals comprise a radio-nuclear loading on liposome and inhibit the tumor growth and metastatic progression of head and neck cancer, lung cancer and brain cancer. The radiopharmaceuticals may be used for treating the mentioned cancers.

Abstract: The present invention discloses a portable routing device. One of the main features of the present invention is that the present invention utilizes a domain name signal as a switch on signal of a routing module of the portable routing device to maintain the off status of the routing module so as to saving power thereby. In another way, the present invention further capable of switching off the routing function thereof by determining if any network source having a higher priority exists so as to save the unnecessary waste of power. By avoiding the unnecessary routing action, the present invention is capable of saving power without affecting the normal use of the user.

Abstract: The present invention relates to a method for detecting cancer initiating cells in living animal body by multimodality reporter gene imaging. In the method of this invention, cells escaping from cell loss during tumor enlargement are identified as cancer initiating cells.

Abstract: A fluorescent fusion protein is provided. The fluorescent fusion protein of the invention comprises a first fluorescent protein with first emission wavelength, a second fluorescent protein with second excitation wavelength and second emission wavelength, and a linker peptide linking the first fusion protein and the second fusion protein, wherein the first emission wavelength overlaps the second excitation wavelength so that the second fluorescent protein exhibits the second emission wavelength after receiving energy. The fluorescent fusion protein of the invention exhibits a stronger fluorescence in the absence of bilivirdin (BV).

Abstract: Embodiments of the present invention disclose a method, user equipment, base station, and system for detecting sharing of a timing advance value, relate to the field of communications technologies, and solve a problem in the prior art that a normal service cannot be provided because a TA value cannot be shared between different uplink CCs. According to the embodiments of the present invention, the user equipment may determine, through a time offset between synchronization of downlink component carriers corresponding to uplink component carriers, that a too large time offset indicates that a same TA value cannot be shared; the base station may calculate a TA value directly through a dedicated preamble sequence, and then compares the TA value with a TA value of one of the component carriers, where a too large difference between the TA values indicates that a same TA value cannot be shared.

Abstract: A method for preventing theft of an electric vehicle includes steps (a) and (b). In step (a), when a switch detector detects that the state of a main switch is an OFF state, and when a rotation detector detects that a drive wheel is rotating, a controller is configured to count a time period of rotation of the drive wheel. In step (b), the controller is configured to enable a locking mechanism for locking the drive wheel from rotation when the time period counted by the controller reaches a preset time period.