Patents by Inventor Yi-Jen Lee

Yi-Jen Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240153033
    Abstract: A method, system, and article is directed to automatic content-dependent image processing algorithm selection.
    Type: Application
    Filed: June 16, 2021
    Publication date: May 9, 2024
    Applicant: Intel Corporation
    Inventors: Chen Wang, Huan Dou, Sang-Hee Lee, Yi-Jen Chiu, Lidong Xu
  • Publication number: 20240132496
    Abstract: An ionic compound, an absorbent and an absorption device are provided. The ionic compound has a structure represented by Formula (I): ABn, ??Formula (I) wherein A is B is R1, R2, R3, R4, R5, and R6 are independently H, C1-6 alkyl group; and n is 1 or 2.
    Type: Application
    Filed: June 9, 2023
    Publication date: April 25, 2024
    Applicant: Industrial Technology Research Institute
    Inventors: Wei-Chih LEE, Yi-Hsiang CHEN, Chih-Hao CHEN, Ai-Yu LIOU, Jyi-Ching PERNG, Jiun-Jen CHEN
  • Publication number: 20240087999
    Abstract: A packaging substrate assembly for fabricating a packaged module can include a packaging substrate having a surface, and an array of conductive pads implemented on the surface. The assembly can further include a conductive post formed over each conductive pad, with the conductive post including a first portion having a lateral dimension formed over the conductive pad and a second portion having a lateral dimension formed over the first portion. In some embodiments, the lateral dimension of the first portion is less than the lateral dimension of the second portion. In some embodiments, a dielectric layer can be implemented over the surface to cover the conductive pads and surround the first portion of each conductive post.
    Type: Application
    Filed: September 8, 2023
    Publication date: March 14, 2024
    Inventors: Chien Jen WANG, Ki Wook LEE, Yi LIU, Shaul BRANCHEVSKY, Cai LIANG
  • Publication number: 20240079524
    Abstract: A semiconductor device comprises a first semiconductor structure, a second semiconductor structure located on the first semiconductor structure, and an active layer located between the first semiconductor structure and the second semiconductor structure. The first semiconductor structure has a first conductivity type, and includes a plurality of first layers and a plurality of second layers alternately stacked. The second semiconductor structure has a second conductivity type opposite to the first conductivity type. The plurality of first layers and the plurality of second layers include indium and phosphorus, and the plurality of first layers and the plurality of second layers respectively have a first indium atomic percentage and a second indium atomic percentage. The second indium atomic percentage is different from the first indium atomic percentage.
    Type: Application
    Filed: September 6, 2023
    Publication date: March 7, 2024
    Inventors: Wei-Jen HSUEH, Shih-Chang LEE, Kuo-Feng HUANG, Wen-Luh LIAO, Jiong-Chaso SU, Yi-Chieh LIN, Hsuan-Le LIN
  • Publication number: 20170145381
    Abstract: The present invention relates generally to a method of generating cells exhibiting multilineage potential and to cells generated thereby. More particularly, the present invention is directed to an in vitro method of generating mammalian stem cells from CD4* mononuclear cells, CD8* mononuclear cells, CD25* mononuclear cells, CD19* mononuclear cells or CD20* mononuclear cells and to cells generated thereby. This finding has now facilitated the design of means for reliably and efficiently generating populations of multilineage potential cells, such as stem cells, for use in a wide variety of clinical and research settings. These uses include, inter alia, the directed differentiation, either in vitro or in vivo, of the subject multilineage potential cells and the therapeutic or prophylactic treatment of a range of conditions either via the administration of the multilineage potential cells of the invention or the more fully differentiated cellular populations derived therefrom.
    Type: Application
    Filed: June 4, 2015
    Publication date: May 25, 2017
    Inventors: Shou-hsiung PAI, Yi-jen LEE, Jah-yao LIU
  • Publication number: 20170007644
    Abstract: The present invention relates to a method of treating a neoplastic condition in a mammal. More particularly, the present invention is directed to a method of treating solid tumours, such as primary tumours, secondary tumours, and metastatic tumours. The method of the present invention is predicated on down-regulating the growth of neoplastic cells by administering stem cells or a population of multilineage progenitor cells (MLPC) which have been generated in vitro.
    Type: Application
    Filed: December 5, 2014
    Publication date: January 12, 2017
    Applicant: Fuwan Pty Ltd.
    Inventors: Shou-hsiung PAI, Yi-jen LEE
  • Publication number: 20150353897
    Abstract: The present invention relates generally to a method of generating cells exhibiting multilineage potential and to cells generated thereby. More particularly, the present invention is directed to an in vitro method of generating mammalian stem cells from CD14+ mononuclear cells and to cells generated thereby. This finding has now facilitated the design of means for reliably and efficiently generating populations of multilineage potential cells, such as stem cells,for use in a wide variety of clinical and research settings. These uses include, inter alia, the directed differentiation, either in vitro or in vivo, of the subject multilineage potential cells and the therapeutic or prophylactic treatment of a range of conditions either via the administration of the multilineage potential cells of the invention or the more fully differentiated cellular populations derived therefrom.
    Type: Application
    Filed: December 6, 2013
    Publication date: December 10, 2015
    Inventors: Shou-Hsiung PAI, Yi-Jen LEE, Chia-Yang SHIAU
  • Publication number: 20100168028
    Abstract: Active fragments of hcrmp1 that are capable of inhibiting cell proliferation, invasive activity, and metastasis of cancer and methods of using the same for treating cancer are disclosed. The method can also be used prior to, or in combination with, the administration a chemotherapy agent. Vectors capable of expressing an hcrmp1, variants of hcrmp1, fragments of hcrmp1 and/or variants of fragments of hcrmp1 are also disclosed.
    Type: Application
    Filed: March 7, 2010
    Publication date: July 1, 2010
    Applicant: ADVPHARMA, INC.
    Inventors: HARN-JING TERNG, YI-JEN LEE, WOAN-JEN LEE
  • Patent number: 7741464
    Abstract: The present invention discloses a method for treating cancer by using hCRMP1 and/or active fragments thereof, as well as the active fragments of hCRMP1 that are capable of inhibiting cell proliferation, invasive activity, and metastasis of cancer. The method can also be used prior to, or in combination with, the administration a chemotherapy agent. A vector capable of expressing an hCRMP1, a variant of hCRMP1, a fragment of hCRMP1 or a variant of a fragment of hCRMP1 is also disclosed.
    Type: Grant
    Filed: March 21, 2008
    Date of Patent: June 22, 2010
    Assignee: Advpharma Inc.
    Inventors: Harn-Jing Terng, Yi-Jen Lee, Woan-Jen Lee
  • Patent number: 7655779
    Abstract: This invention provides a transcription unit which is isolated from the upstream nucleic acid sequence of the collapsing response mediator protein-1 (CRMP-1) gene, an invasion-suppressor gene. The transcription unit contains a nucleic acid regulatory sequence which demonstrates promoter and/or regulatory activities (such as providing a transcription factor binding site) to enhance the expression of the CRMP-1 and/or a reporter protein. The invention also provides a DNA construct containing this transcription unit which can be transfected into a host cell. Additionally, the invention provides methods to enhance the expression of CRMP-1 and/or the reporter protein. The over-expression of CRMP-1 in a cancer cell can inhibit the metastasis of the cancer cell.
    Type: Grant
    Filed: April 19, 2007
    Date of Patent: February 2, 2010
    Assignee: Advpharma Inc.
    Inventors: Pan-Chyr Yang, Tse-Ming Hong, Jeremy J. W. Chen, Cheng-Chung Wu, Jin-Yuan Shin, Yi-Jen Lee
  • Publication number: 20080287361
    Abstract: The present invention discloses a method for treating cancer by using hCRMP1 and/or active fragments thereof, as well as the active fragments of hCRMP1 that are capable of inhibiting cell proliferation, invasive activity, and metastasis of cancer. The method can also be used prior to, or in combination with, the administration a chemotherapy agent. A vector capable of expressing an hCRMP1, a variant of hCRMP1, a fragment of hCRMP1 or a variant of a fragment of hCRMP1 is also disclosed.
    Type: Application
    Filed: March 21, 2008
    Publication date: November 20, 2008
    Inventors: Harn-Jing Terng, Yi-Jen Lee, Woan-Jen Lee
  • Patent number: 7211660
    Abstract: This invention provides a transcription unit which is isolated from the upstream nucleic acid sequence of the collapsing response mediator protein-1 (CRMP-1) gene, an invasion-suppressor gene. The transcription unit contains a nucleic acid regulatory sequence which demonstrates promoter and/or regulatory activities (such as providing a transcription factor binding site) to enhance the expression of the CRMP-1 and/or a reporter protein. The invention also provides a DNA construct containing this transcription unit which can be transfected into a host cell. Additionally, the invention provides methods to enhance the expression of CRMP-1 and/or the reporter protein. The over-expression of CRMP-1 in a cancer cell can inhibit the metastasis of the cancer cell.
    Type: Grant
    Filed: February 7, 2005
    Date of Patent: May 1, 2007
    Assignee: Advpharma Inc.
    Inventors: Pan-Chyr Yang, Tse-Ming Hong, Jeremy J. W. Chen, Cheng-Chung Wu, Jin-Yuan Shin, Yi-Jen Lee
  • Publication number: 20050182016
    Abstract: This invention provides a transcription unit which is isolated from the upstream nucleic acid sequence of the collapsing response mediator protein-1 (CRMP-1) gene, an invasion-suppressor gene. The transcription unit contains a nucleic acid regulatory sequence which demonstrates promoter and/or regulatory activities (such as providing a transcription factor binding site) to enhance the expression of the CRMP-1 and/or a reporter protein. The invention also provides a DNA construct containing this transcription unit which can be transfected into a host cell. Additionally, the invention provides methods to enhance the expression of CRMP-1 and/or the reporter protein. The over-expression of CRMP-1 in a cancer cell can inhibit the metastasis of the cancer cell.
    Type: Application
    Filed: February 7, 2005
    Publication date: August 18, 2005
    Inventors: Pan-Chyr Yang, Tse-Ming Hong, Jeremy Chen, Cheng-Chung Wu, Jin-Yuan Shin, Yi-Jen Lee