Patents by Inventor Yiliang Li

Yiliang Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12258360
    Abstract: Embodiments of the instant disclosure relate to novel methods and compositions for treating tumors resistant to one or more anticancer drugs, such as platinum-based chemotherapeutics.
    Type: Grant
    Filed: September 14, 2022
    Date of Patent: March 25, 2025
    Assignee: The George Washington University
    Inventors: Wenge Zhu, Jing Li, Yiliang Li
  • Publication number: 20230129381
    Abstract: Embodiments of the instant disclosure relate to novel methods and compositions for treating tumors resistant to one or more anticancer drugs, such as platinum-based chemotherapeutics.
    Type: Application
    Filed: September 14, 2022
    Publication date: April 27, 2023
    Inventors: WENGE ZHU, JING LI, YILIANG LI
  • Publication number: 20230012172
    Abstract: Embodiments of the instant disclosure relate to novel methods and compositions for treating tumors resistant to platinum-based chemotherapy. In certain embodiments, methods of treating tumors herein can include administering an effective amount of at least one ursolic acid derivative. In certain embodiments, methods of treating tumors herein can include administering an effective amount of at least one ursolic acid derivative in combination with at least one platinum-based chemotherapeutic separately or in a combination therapy. In some embodiments, methods of treating tumors disclosed herein can include screening and/or selecting a subject suitable for treatment on the basis of SENP1 tumor expression. In other embodiments, methods of treating tumors can include administering a composition disclosed herein to a subject, the composition having a combination of at least one ursolic acid derivative and at least one platinum-based chemotherapeutic.
    Type: Application
    Filed: August 22, 2022
    Publication date: January 12, 2023
    Inventors: Wenge ZHU, Jing LI, Ruiqin WU, Yiliang LI
  • Patent number: 10626022
    Abstract: An integrated apparatus for chemical precipitation and rapid filtration of water samples. The invention relates to an apparatus for chemical precipitation and filtration of water samples. The integrated apparatus includes a reaction vessel, a lid of reaction vessel, a opening for reagent addition and gas leakage, an aerating tube, a support, a liquid phase remover, a solid phase collector, a control cover of the liquid phase remover, and a control cover of the solid phase collector.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: April 21, 2020
    Assignee: Third Institute of Oceanography, State Oceanic Administration
    Inventors: Jianhua He, Yiliang Li, Dekun Huang, Feng Lin, Wu Men, Wen Yu, Fangfang Deng, Jing Lin, Fenfen Wang, Jialin Ni, Tao Yu
  • Publication number: 20180362363
    Abstract: An integrated apparatus for chemical precipitation and rapid filtration of water samples. The invention relates to an apparatus for chemical precipitation and filtration of water samples. The integrated apparatus includes a reaction vessel, a lid of reaction vessel, a opening for reagent addition and gas leakage, an aerating tube, a support, a liquid phase remover, a solid phase collector, a control cover of the liquid phase remover, and a control cover of the solid phase collector.
    Type: Application
    Filed: April 1, 2016
    Publication date: December 20, 2018
    Applicant: Third Institute of Oceanography, State Oceanic Administration
    Inventors: Jianhua He, Yiliang Li, Dekun Huang, Feng Lin, Wu Men, Wen Yu, Fangfang Deng, Jing Lin, Fenfen Wang, Jialin Ni, Tao Yu
  • Patent number: 9768333
    Abstract: The invention is directed to a method for producing non-oxide semiconductor nanoparticles, the method comprising: (a) subjecting a combination of reaction components to conditions conducive to microbially-mediated formation of non-oxide semiconductor nanoparticles, wherein said combination of reaction components comprises i) anaerobic microbes, ii) a culture medium suitable for sustaining said anaerobic microbes, iii) a metal component comprising at least one type of metal ion, iv) a non-metal component comprising at least one non-metal selected from the group consisting of S, Se, Te, and As, and v) one or more electron donors that provide donatable electrons to said anaerobic microbes during consumption of the electron donor by said anaerobic microbes; and (b) isolating said non-oxide semiconductor nanoparticles, which contain at least one of said metal ions and at least one of said non-metals.
    Type: Grant
    Filed: April 7, 2014
    Date of Patent: September 19, 2017
    Assignees: UT-BATTELLE, LLC, UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION
    Inventors: Tommy J. Phelps, Robert J. Lauf, Ji-Won Moon, Adam Justin Rondinone, Lonnie J. Love, Chad Edward Duty, Andrew Stephen Madden, Yiliang Li, Ilia N. Ivanov, Claudia Jeanette Rawn
  • Publication number: 20140220654
    Abstract: The invention is directed to a method for producing non-oxide semiconductor nanoparticles, the method comprising: (a) subjecting a combination of reaction components to conditions conducive to microbially-mediated formation of non-oxide semiconductor nanoparticles, wherein said combination of reaction components comprises i) anaerobic microbes, ii) a culture medium suitable for sustaining said anaerobic microbes, iii) a metal component comprising at least one type of metal ion, iv) a non-metal component comprising at least one non-metal selected from the group consisting of S, Se, Te, and As, and v) one or more electron donors that provide donatable electrons to said anaerobic microbes during consumption of the electron donor by said anaerobic microbes; and (b) isolating said non-oxide semiconductor nanoparticles, which contain at least one of said metal ions and at least one of said non-metals.
    Type: Application
    Filed: April 7, 2014
    Publication date: August 7, 2014
    Inventors: Tommy J. Phelps, Robert J. Lauf, Ji-Won Moon, Adam Justin Rondinone, Lonnie J. Love, Chad Edward Duty, Andrew Stephen Madden, Yiliang Li, Ilia N. Ivanov, Claudia Jeanette Rawn
  • Patent number: 8759053
    Abstract: The invention is directed to a method for producing non-oxide semiconductor nanoparticles, the method comprising: (a) subjecting a combination of reaction components to conditions conducive to microbially-mediated formation of non-oxide semiconductor nanoparticles, wherein said combination of reaction components comprises i) anaerobic microbes, ii) a culture medium suitable for sustaining said anaerobic microbes, iii) a metal component comprising at least one type of metal ion, iv) a non-metal component containing at least one non-metal selected from the group consisting of S, Se, Te, and As, and v) one or more electron donors that provide donatable electrons to said anaerobic microbes during consumption of the electron donor by said anaerobic microbes; and (b) isolating said non-oxide semiconductor nanoparticles, which contain at least one of said metal ions and at least one of said non-metals.
    Type: Grant
    Filed: February 3, 2009
    Date of Patent: June 24, 2014
    Assignees: UT-Battelle, LLC, University of Tennessee Research Foundation
    Inventors: Tommy J. Phelps, Robert J. Lauf, Ji Won Moon, Adam J. Rondinone, Lonnie J. Love, Chad Edward Duty, Andrew Stephen Madden, Yiliang Li, Ilia N. Ivanov, Claudia Jeanette Rawn
  • Patent number: 8481577
    Abstract: The present invention relates to the field of drugs associated with treating diabetes. Particularly, the present invention relates to a dipeptidyl peptidase-IV inhibitor having the structure shown by formula (I), which contains amide thiazole structure and has an effect on treating diabetes, and a preparation method and a pharmaceutical composition containing it, as well as use thereof in manufacture of the drugs for treating the diabetes, wherein, R1 is methyl; R2 is phenyl; phenyl, 2-thienyl substituted in a mono-substituted, bi-substituted manner by fluorine and methyl.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: July 9, 2013
    Assignee: Tianjin Institute of Pharmaceutical Research
    Inventors: Guilong Zhao, Weiren Xu, Yuli Wang, Lida Tang, Yiliang Li, Meixiang Zou, Wei Liu, Hua Shao, Chubing Tan, Peng Liu
  • Publication number: 20110281922
    Abstract: The present invention relates to the field of drugs associated with treating diabetes. Particularly, the present invention relates to a dipeptidyl peptidase-IV inhibitor having the structure shown by formula (I), which contains amide thiazole structure and has an effect on treating diabetes, and a preparation method and a pharmaceutical composition containing it, as well as use thereof in manufacture of the drugs for treating the diabetes, wherein, R1 is methyl; R2 is phenyl; phenyl, 2-thienyl substituted in a mono-substituted, bi-substituted manner by fluorine and methyl.
    Type: Application
    Filed: June 16, 2011
    Publication date: November 17, 2011
    Applicant: TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH
    Inventors: Guilong ZHAO, Weiren Xu, Yuli Wang, Lida Tang, Yiliang Li, Meixiang Zou, Wei Liu, Hua Shao, Chubing Tan, Peng Liu
  • Publication number: 20100330367
    Abstract: The invention is directed to a method for producing non-oxide semiconductor nanoparticles, the method comprising: (a) subjecting a combination of reaction components to conditions conducive to microbially-mediated formation of non-oxide semiconductor nanoparticles, wherein said combination of reaction components comprises i) anaerobic microbes, ii) a culture medium suitable for sustaining said anaerobic microbes, iii) a metal component comprising at least one type of metal ion, iv) a non-metal component comprising at least one non-metal selected from the group consisting of S, Se, Te, and As, and v) one or more electron donors that provide donatable electrons to said anaerobic microbes during consumption of the electron donor by said anaerobic microbes; and (b) isolating said non-oxide semiconductor nanoparticles, which contain at least one of said metal ions and at least one of said non-metals.
    Type: Application
    Filed: September 2, 2010
    Publication date: December 30, 2010
    Applicant: UT-BATTELLE, LLC
    Inventors: Tommy J. Phelps, Robert J. Lauf, Ji Won Moon, Adam J. Rondinone, Lonnie J. Love, Chad Edward Duty, Andrew Stephen Madden, Yiliang Li, Ilia N. Ivanov, Claudia Jeanette Rawn
  • Publication number: 20100193752
    Abstract: The invention is directed to a method for producing non-oxide semiconductor nanoparticles, the method comprising: (a) subjecting a combination of reaction components to conditions conducive to microbially-mediated formation of non-oxide semiconductor nanoparticles, wherein said combination of reaction components comprises i) anaerobic microbes, ii) a culture medium suitable for sustaining said anaerobic microbes, iii) a metal component comprising at least one type of metal ion, iv) a non-metal component containing at least one non-metal selected from the group consisting of S, Se, Te, and As, and v) one or more electron donors that provide donatable electrons to said anaerobic microbes during consumption of the electron donor by said anaerobic microbes; and (b) isolating said non-oxide semiconductor nanoparticles, which contain at least one of said metal ions and at least one of said non-metals.
    Type: Application
    Filed: February 3, 2009
    Publication date: August 5, 2010
    Applicant: UT-BATTELLE, LLC
    Inventors: Tommy J. Phelps, Robert J. Lauf, Ji Won Moon, Adam J. Rondinone, Lonnie J. Love, Chad Edward Duty, Andrew Stephen Madden, Yiliang Li, Ilia N. Ivanov, Claudia Jeanette Rawn