Patents by Inventor Yi Mok

Yi Mok has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEW COMPOUNDS AND METHODS
    Publication number: 20230014226
    Abstract: The present invention relates to compounds of Formula (I) or a pharmaceutically acceptable salt, solvate, hydrate, tautomer, optical isomer, N-oxide, and/or prodrug thereof. The present invention also relates to pharmaceutical compositions comprising the compounds of the invention, and to their use in the treatment or prevention of medical conditions in which inhibition of c-ABL is beneficial.
    Type: Application
    Filed: June 24, 2020
    Publication date: January 19, 2023
    Inventors: Rebecca Paul, Mark Rackham, Yi Mok, Marton Vass, Joshua Meyers, Andrew Cronin, Ajay Mandal
  • Quinoline derivatives as inhibitors of heat shock factor 1 pathway activity
    Patent number: 10647678
    Abstract: The present invention relates to compounds of formula I wherein R, R4 and Q are each as defined herein. The compounds of the present invention are inhibitors of heat shock factor 1 pathway (HSF1 pathway). In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.
    Type: Grant
    Filed: April 1, 2016
    Date of Patent: May 12, 2020
    Assignee: Cancer Research Technology Limited
    Inventors: Keith Jones, Matthew Cheeseman, Nicola Chessum, Elisa Pasqua, Lindsay Evans, Michael Tucker, Birgit Wilding, Ngai Yi Mok
  • QUINOLINE DERIVATIVES AS INHIBITORS OF HEAT SHOCK FACTOR 1 PATHWAY ACTIVITY
    Publication number: 20180093955
    Abstract: The present invention relates to compounds of formula I wherein R, R4 and Q are each as defined herein. The compounds of the present invention are inhibitors of heat shock factor 1 pathway (HSF1 pathway). In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: April 1, 2016
    Publication date: April 5, 2018
    Inventors: Keith Jones, Matthew Cheeseman, Nicola Chessum, Elise Pasqua, Lindsay Evans, Michael Tucker, Birgit Wilding, Ngal Yi Mok