Patents by Inventor Yi Na YOON

Yi Na YOON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12029730
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating cancer, a radiosensitizer composition for treating cancer, and a health functional food for preventing or improving cancer, which comprise N-1H-benzimidazol-2-yl-3-(1H-pyrrol-1-yl) benzamide, a derivative thereof, or a pharmaceutically acceptable salt thereof as an active ingredient. The pharmaceutical composition comprising N-1H-benzimidazol-2-yl-3-(1H-pyrrol-1-yl) benzamide or a derivative thereof as an active ingredient according to the present invention arrests the mitosis of cancer cells to prevent proliferation and at the same time, to exhibit low toxicity in normal cell lines and induce apoptosis only in cancer cell lines, so it can be used as an effective anticancer agent. In addition, the N-1H-benzimidazol-2-yl-3-(1H-pyrrol-1-yl) benzamide of the present invention can increase the sensitivity of the treated cancer cells to radiation, so it can be used as a radiosensitizer composition for cancer treatment.
    Type: Grant
    Filed: September 3, 2019
    Date of Patent: July 9, 2024
    Assignee: KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES
    Inventors: Jae Sung Kim, Ah Young Kim, Sang Gu Hwang, Jie Young Song, Yi Na Yoon
  • Publication number: 20210379022
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating cancer, a radiosensitizer composition for treating cancer, and a health functional food for preventing or improving cancer, which comprise N-1H-benzimidazol-2-yl-3-(1H-pyrrol-1-yl) benzamide, a derivative thereof, or a pharmaceutically acceptable salt thereof as an active ingredient. The pharmaceutical composition comprising N-1H-benzimidazol-2-yl-3-(1H-pyrrol-1-yl) benzamide or a derivative thereof as an active ingredient according to the present invention arrests the mitosis of cancer cells to prevent proliferation and at the same time, to exhibit low toxicity in normal cell lines and induce apoptosis only in cancer cell lines, so it can be used as an effective anticancer agent. In addition, the N-1H-benzimidazol-2-yl-3-(1H-pyrrol-1-yl) benzamide of the present invention can increase the sensitivity of the treated cancer cells to radiation, so it can be used as a radiosensitizer composition for cancer treatment.
    Type: Application
    Filed: September 3, 2019
    Publication date: December 9, 2021
    Applicant: KOREA INSTITUTE OF RADIOLOGICAL & MEDICAL SCIENCES
    Inventors: Jae Sung KIM, Ah Young KIM, Sang Gu HWANG, Jie Young SONG, Yi Na YOON
  • Publication number: 20200094051
    Abstract: Provided is a cancer treating device including a signal generator, a temperature sensor electrically connected to the signal generator, and a pair of electrodes which receive an AC voltage from the signal generator, wherein the signal generator is configured to generate an electric field between the electrodes so as to change orientations of ferroelectric particles inside a cancer cell, the temperature sensor measures a temperature around the cancer cell, and the signal generator may be configured to change the intensity of the electric field on the basis of the measured temperature.
    Type: Application
    Filed: September 19, 2019
    Publication date: March 26, 2020
    Inventors: Hyung Ju PARK, Dae-Sik LEE, Jae-Sung KIM, Yi Na YOON