Patents by Inventor Yi-Pei Chen

Yi-Pei Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monacolin K biosynthesis genes
    Patent number: 7482157
    Abstract: Cholesterol inhibitor produced by Monascus, monacolin k, is a secondary metabolite of polyketides. The invention provides probes specific to monacolin k biosynthesis gene cluster. BAC clones having putative monacolin k gene cluster were screened from BAC (bacterial artificial chromosome) library, and sequencing and annotation were performed on these clones. The results show that 2 polyketide synthase (PKS) genes and 7 regulatory genes related to monacolin k synthesis were obtained. Full-length cDNAs of these genes were then obtained by RT-PCR and cloned to expression vectors for the expression of these genes.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: January 27, 2009
    Assignee: Food Industry Research & Development Institute
    Inventors: Yi-Pei Chen, Li-Ling Liaw, Chun-Lin Wang, Chung-Tsai Lee, Ing-Er Hwang, Ching-Ping Tseng, Gwo-Fang Yuan
  • Fungi non-LTR retrotransposons and methods related thereto
    Patent number: 7465792
    Abstract: Retrotransposons and methods related thereto. The retrotransposon comprises a nucleotide sequence selected from a group consisting of a nucleotide sequence of SEQ ID NO: 1, a nucleotide sequence of SEQ ID NO: 2, a nucleotide sequence of SEQ ID NO: 3, and a nucleotide sequence encoding a polypeptide of an amino acid sequence of SEQ ID NO: 4.
    Type: Grant
    Filed: July 13, 2005
    Date of Patent: December 16, 2008
    Assignee: Food Industry Research & Development Institute
    Inventors: Yi-Pei Chen, Li-Ling Liaw, Chun-Lin Wang, Ching-Ping Tseng, Gwo-Fang Yuan
  • Fungi non-LTR retrotransposons and methods related thereto
    Publication number: 20060148088
    Abstract: Retrotransposons and methods related thereto. The retrotransposon comprises a nucleotide sequence selected from a group consisting of a nucleotide sequence of SEQ ID NO: 1, a nucleotide sequence of SEQ ID NO: 2, a nucleotide sequence of SEQ ID NO: 3, and a nucleotide sequence encoding a polypeptide of an amino acid sequence of SEQ ID NO: 4.
    Type: Application
    Filed: July 13, 2005
    Publication date: July 6, 2006
    Inventors: Yi-Pei Chen, Li-Ling Liaw, Chun-Lin Wang, Ching-Ping Tseng, Gwo-Fang Yuan
  • Monacolin K biosynthesis genes
    Publication number: 20050227262
    Abstract: Cholesterol inhibitor produced by Monascus, monacolin k, is a secondary metabolite of polyketides. The invention provides probes specific to monacolin k biosynthesis gene cluster. BAC clones having putative monacolin k gene cluster were screened from BAC (bacterial artificial chromosome) library, and sequencing and annotation were performed on these clones. The results show that 2 polyketide synthase (PKS) genes and 7 regulatory genes related to monacolin k synthesis were obtained. Full-length cDNAs of these genes were then obtained by RT-PCR and cloned to expression vectors for the expression of these genes.
    Type: Application
    Filed: December 23, 2004
    Publication date: October 13, 2005
    Inventors: Yi-Pei Chen, Li-Ling Liaw, Chun-Lin Wang, Chung-Tsai Lee, Ing-Er Hwang, Ching-Ping Tseng, Gwo-Fang Yuan