Patents by Inventor Yixian LI

Yixian LI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240131170
    Abstract: A formulation includes a plurality of polymers including a hydrophobic polymer backbone (for example, formed via radical polymerization), a first plurality of pendant groups attached to the hydrophobic polymer backbone and including at least one cationic group, and a second plurality of pendant groups attached to the hydrophobic polymer backbone and including at least one hydrophilic polymer, a first therapeutic compound, and a second therapeutic compound, wherein the second therapeutic compound is different from the first therapeutic compound and includes a nucleic acid.
    Type: Application
    Filed: December 14, 2023
    Publication date: April 25, 2024
    Inventors: Song Li, Jingjing Sun, Yichao Chen, Yixian Huang, Yanhua Liu, Binfeng Lu
  • Publication number: 20230391362
    Abstract: The disclosed techniques include: obtaining traveling state information of the autonomous vehicle; obtaining, in response to confirming that there is a traffic object within a preset range for the autonomous vehicle, true motion state information of the traffic object; determining a first control decision for indicating whether the autonomous vehicle is to avoid the traffic object based on the traveling state information of the autonomous vehicle and the true motion state information of the traffic object; predicting first predictive motion state information of the traffic object within a first preset duration based on the true motion state information of the traffic object and the first control decision; and determining a second control decision for the autonomous vehicle based on the traveling state information of the autonomous vehicle and the first predictive motion state information of the traffic object.
    Type: Application
    Filed: August 18, 2023
    Publication date: December 7, 2023
    Inventors: Changchun LIU, Yabo SU, Yifeng PAN, Yixian LI, Han DENG, Jing YANG, Chao WANG, Zhenguang ZHU, Liang PENG
  • Patent number: 11285970
    Abstract: A vehicle track prediction method and device, a storage medium and a terminal device are provided. The method includes: determining an obstacle vehicle entering a junction region in a case that an autonomous vehicle enters the junction region; acquiring historical traveling data of the obstacle vehicle in the junction region; predicting a potential track of the obstacle vehicle according to the historical traveling data and a current traveling state of the obstacle vehicle; and predicting a track of the autonomous vehicle in the junction region according to the potential track of the obstacle vehicle and a current traveling state of the autonomous vehicle. A decision making accuracy in self-driving may be effectively improved, and a driving risk may be reduced.
    Type: Grant
    Filed: February 19, 2020
    Date of Patent: March 29, 2022
    Assignee: Apollo Intelligent Driving Technology (Beijing) Co., Ltd.
    Inventors: Yifeng Pan, Xuguang Yang, Feiyi Jiang, Zhongtao Chen, Yixian Li
  • Publication number: 20200290651
    Abstract: A vehicle track prediction method and device, a storage medium and a terminal device are provided. The method includes: determining an obstacle vehicle entering a junction region in a case that an autonomous vehicle enters the junction region; acquiring historical traveling data of the obstacle vehicle in the junction region; predicting a potential track of the obstacle vehicle according to the historical traveling data and a current traveling state of the obstacle vehicle; and predicting a track of the autonomous vehicle in the junction region according to the potential track of the obstacle vehicle and a current traveling state of the autonomous vehicle. A decision making accuracy in self-driving may be effectively improved, and a driving risk may be reduced.
    Type: Application
    Filed: February 19, 2020
    Publication date: September 17, 2020
    Inventors: Yifeng Pan, Xuguang Yang, Feiyi Jiang, Zhongtao Chen, Yixian Li
  • Patent number: 10485763
    Abstract: The present invention provides: a composition for transarterial chemoembolization, comprising two types of biodegradable microbeads having different anticancer drug release characteristics; and a preparation method therefor. According to the present invention, a composition for transarterial chemoembolization exhibiting a desired anticancer drug release characteristic can be effectively prepared by controlling the mixing ratio of first and second biodegradable microbeads. Therefore, the present invention can be usefully applied to the transarterial chemoembolization of liver cancer.
    Type: Grant
    Filed: May 14, 2015
    Date of Patent: November 26, 2019
    Assignee: UTAH-INHA DDS & ADVANCED THERAPEUTICS RESEARCH CEN
    Inventors: Don Haeng Lee, Young Hwan Park, Se Yoon Kim, Yixian Li
  • Publication number: 20190274957
    Abstract: The present invention relates to: biodegradable microbeads with improved anticancer drug adsorptivity, containing albumin and dextran sulfate; a preparation method therefor; and a method for treating cancer using the same. The microbeads of the present invention is prepared from a biocompatible and biodegradable polymer so as to be safe to the human body, and can effectively inhibit the growth of a tumor by effectively blocking a blood vessel which supplies nutrition to a liver tumor and continuously releasing an anticancer drug adsorbed on surfaces of the beads. Therefore, the present invention can be useful for liver cancer chemoembolization.
    Type: Application
    Filed: May 7, 2019
    Publication date: September 12, 2019
    Inventors: Se Yoon KIM, Don Haeng LEE, Yixian LI
  • Patent number: 9999676
    Abstract: The present invention relates to a biodegradable microbead having improved adsorptive power to anticancer drugs, to a method for preparing same, and to a method for treating cancer using same. According to the present invention, a rigid bead having excellent adsorptive power to anticancer drugs can be prepared through cross-linking and an amide bond between an albumin and an anionic polymer. Also, the microbead of the present invention is prepared by a biocompatible and biodegradable polymer so as to be safe when applied to the human body. Further, the microbead of the present invention can effectively inhibit the growth of a tumor by effectively blocking a blood vessel which supplies nutrients to a liver tumor, while continuously releasing anticancer drugs which are adsorbed into the surface of the bead. Thus, the present invention can be usefully applied to a chemoembolization of liver cancer.
    Type: Grant
    Filed: November 15, 2013
    Date of Patent: June 19, 2018
    Assignee: UTAH-INHA DDS & ADVANCED THERAPEUTICS RESEARCH CENTER
    Inventors: Se Yoon Kim, Don Haeng Lee, Yixian Li
  • Publication number: 20170165202
    Abstract: The present invention provides: a composition for transarterial chemoembolization, comprising two types of biodegradable microbeads having different anticancer drug release characteristics; and a preparation method therefor. According to the present invention, a composition for transarterial chemoembolization exhibiting a desired anticancer drug release characteristic can be effectively prepared by controlling the mixing ratio of first and second biodegradable microbeads. Therefore, the present invention can be usefully applied to the transarterial chemoembolization of liver cancer.
    Type: Application
    Filed: May 14, 2015
    Publication date: June 15, 2017
    Inventors: Don Haeng LEE, Young Hwan PARK, Se Yoon KIM, Yixian LI
  • Publication number: 20150352050
    Abstract: The present invention relates to: biodegradable microbeads with improved anticancer drug adsorptivity, containing albumin and dextran sulfate; a preparation method therefor; and a method for treating cancer using the same. The microbeads of the present invention is prepared from a biocompatible and biodegradable polymer so as to be safe to the human body, and can effectively inhibit the growth of a tumor by effectively blocking a blood vessel which supplies nutrition to a liver tumor and continuously releasing an anticancer drug adsorbed on surfaces of the beads. Therefore, the present invention can be useful for liver cancer chemoembolization.
    Type: Application
    Filed: November 15, 2013
    Publication date: December 10, 2015
    Inventors: Se Yoon KIM, Don Haeng LEE, Yixian LI
  • Publication number: 20150297732
    Abstract: The present invention relates to a biodegradable microbead having improved adsorptive power to anticancer drugs, to a method for preparing same, and to a method for treating cancer using same. According to the present invention, a rigid bead having excellent adsorptive power to anticancer drugs can be prepared through cross-linking and an amide bond between an albumin and an anionic polymer. Also, the microbead of the present invention is prepared by a biocompatible and biodegradable polymer so as to be safe when applied to the human body. Further, the microbead of the present invention can effectively inhibit the growth of a tumor by effectively blocking a blood vessel which supplies nutrients to a liver tumor, while continuously releasing anticancer drugs which are adsorbed into the surface of the bead. Thus, the present invention can be usefully applied to a chemoembolization of liver cancer.
    Type: Application
    Filed: November 15, 2013
    Publication date: October 22, 2015
    Inventors: Se Yoon KIM, Don Haeng LEE, Yixian LI