Abstract: A drug carrier with a property of crossing the blood-brain barrier comprises an extracellular vesicle with a human leukocyte antigen-G antibody on its surface. This carrier can serve as a pharmaceutical composition for promoting apoptosis of brain tumor cells, inhibiting growth of brain tumor cells, or reducing expression of O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells. These effects contribute to the treatment of glioblastoma multiforme (GBM).

Abstract: The present disclosure provides a fusion protein and the nucleic acid encoding sequence thereof, and uses of the same. The fusion protein of the present disclosure achieves the effect of treating cancer, immunoregulation and activating immune cells through various efficacy experiments.

Abstract: In one example in accordance with the present disclosure, an electronic device is described. An example electronic device includes a calibration engine to receive display calibration measurement data generated by a calibration device for a display device. The example calibration engine is to determine a calibrated color profile to cause the display device to operate according to a baseline light condition based on the display calibration measurement data. The example electronic device also includes a color preset engine to generate a color preset for the display device based on the baseline light condition.

Abstract: A charging apparatus includes an antenna, a receiver, and a battery. The battery is charged by a harvester, which converts wireless energy sent by antenna to direct current and charges the battery. The harvester includes a sensor coil, a rectifier and voltage regulating filter. The wireless energy is converted by the sensor coil to alternating current (AC). The rectifier is electrically connected to the sensor coil for converting AC to direct current (DC). The voltage regulating filter is electrically connected to the rectifier to regulate DC. The battery can be charged by the wireless charge apparatus.

Abstract: A bi-directional smooth transition switch with bumpless transfer is disclosed. It is composed of two feedback loops, each with feedback and forward-loop compensators. During loop operation, one feedback loop is active, while the other is inactive. The smooth transition switch operates in the following manner. The switch output is measured. Next, an error signal is formed as the difference between the forward-loop compensator output and the switch output, which is fed to the input of a high gain feedback compensator. The output of the feedback compensator is a feedback signal. When no switching occurs, the feedback signal remains zero in the active loop, and the output signal of the inactive loop will track the output signal of the active loop. When the switchover occurs, the inactive loop will replace the original active loop and provide smooth transition switch's output.

Abstract: The present invention involves a system and method of controlling a steering wheel for simulated steering feel on a steering wheel of a vehicle with front road wheels in a steer-by-wire system. The method includes sensing actual torsion on the steering wheel, comparing the actual torsion to a threshold torque value, sensing actual angular velocity of the steering wheel, and comparing the actual angular velocity to a threshold angular velocity. The method further includes generating a simulated steering feel torque on the steering wheel, if the actual torsion is greater than the threshold torque value and the actual angular velocity is less than the threshold angular velocity. The method further comprises returning the steering wheel to the center position at a specified angular velocity, if the actual torsion is less than the threshold torque value and the actual angular velocity is greater than the threshold angular velocity.

Abstract: This invention describes a bi-directional smooth transition switch with bumpless transfer. It is composed of two feedback loops. Each loop has feedback and forward-loop compensators. During loop operation, one feedback loop is active, while the other is inactive. The smooth transition switch operates in the following manner. The switch output is measured. Next, an error signal is formed as the difference between the forward-loop compensator output and the switch output. This error signal is fed to the input of a high gain feedback compensator. The output of the feedback compensator is a feedback signal. When no switching occurs, the feedback signal remains zero in the active loop, and the output signal of the inactive loop will track the output signal of the active loop. When the switchover occurs, the inactive loop will replace the original active loop and provide smooth transition switch's output.

Abstract: The present invention involves a system and method of controlling a steering wheel for simulated steering feel on a steering wheel of a vehicle with front road wheels in a steer-by-wire system. The method includes sensing actual torsion on the steering wheel, comparing the actual torsion to a threshold torque value, sensing actual angular velocity of the steering wheel, and comparing the actual angular velocity to a threshold angular velocity. The method further includes generating a simulated steering feel torque on the steering wheel, if the actual torsion is greater than the threshold torque value and the actual angular velocity is less than the threshold angular velocity. The method further comprises returning the steering wheel to the center position at a specified angular velocity, if the actual torsion is less than the threshold torque value and the actual angular velocity is greater than the threshold angular velocity.

Abstract: The present invention involves a system and method of controlling a steering wheel for simulated steering feel on a steering wheel of a vehicle with front road wheels in a steer-by-wire system. The method includes sensing actual torsion on the steering wheel, comparing the actual torsion to a threshold torque value, sensing actual angular velocity of the steering wheel, and comparing the actual angular velocity to a threshold angular velocity. The method further includes generating a simulated steering feel torque on the steering wheel, if the actual torsion is greater than the threshold torque value and the actual angular velocity is less than the threshold angular velocity. The method further comprises returning the steering wheel to the center position at a specified angular velocity, if the actual torsion is less than the threshold torque value and the actual angular velocity is greater than the threshold angular velocity.

Abstract: The present invention involves a system and method of controlling a steering wheel for simulated steering feel on a steering wheel of a vehicle with front road wheels in a steer-by-wire system. The method includes sensing actual torsion on the steering wheel, comparing the actual torsion to a threshold torque value, sensing actual angular velocity of the steering wheel, and comparing the actual angular velocity to a threshold angular velocity. The method further includes generating a simulated steering feel torque on the steering wheel, if the actual torsion is greater than the threshold torque value and the actual angular velocity is less than the threshold angular velocity. The method further comprises returning the steering wheel to the center position at a specified angular velocity, if the actual torsion is less than the threshold torque value and the actual angular velocity is greater than the threshold angular velocity.

Abstract: The present invention involves a system and method of controlling a steering wheel for simulated steering feel on a steering wheel of a vehicle with front road wheels in a steer-by-wire system. The method includes sensing actual torsion on the steering wheel, comparing the actual torsion to a threshold torque value, sensing actual angular velocity of the steering wheel, and comparing the actual angular velocity to a threshold angular velocity. The method further includes generating a simulated steering feel torque on the steering wheel, if the actual torsion is greater than the threshold torque value and the actual angular velocity is less than the threshold angular velocity. The method further comprises returning the steering wheel to the center position at a specified angular velocity, if the actual torsion is less than the threshold torque value and the actual angular velocity is greater than the threshold angular velocity.

Abstract: The present invention involves a system and method of controlling a steering wheel for simulated steering feel on a steering wheel of a vehicle with front road wheels in a steer-by-wire system. The method includes sensing actual torsion on the steering wheel, comparing the actual torsion to a threshold torque value, sensing actual angular velocity of the steering wheel, and comparing the actual angular velocity to a threshold angular velocity. The method further includes generating a simulated steering feel torque on the steering wheel, if the actual torsion is greater than the threshold torque value and the actual angular velocity is less than the threshold angular velocity. The method further comprises returning the steering wheel to the center position at a specified angular velocity, if the actual torsion is less than the threshold torque value and the actual angular velocity is greater than the threshold angular velocity.

Abstract: A method of monitoring and deactivating a steer-by-wire system capable of several performance levels of a vehicle, including measuring an angle of an actuated road wheel of the vehicle, a steering angle of a steering device of the vehicle, and a velocity of the vehicle; determining and storing an acceptable angle range based on the measured steering angle of the steering device and the measured velocity; comparing the measured angle of the actuated road wheel to the acceptable angle range; and implementing a procedure based on the comparison of the measured angle to the acceptable angle range that complies with a particular set of rules.