Abstract: The present invention generally relates to sensitizer compounds and their use in combination with Tyrosine Kinase Inhibitors (TKIs) for sensitizing tumor, cancer or pre-cancerous cells to TKI treatment. In particular, the present invention relates to administration regimes that combine TKIs such as Gefitinib or Icotinib with TKI-sensitizing DZ1 esters and amides conjugated to statin or platin-based drugs, or to Artemisinin, including, without limitation: DZ1-Simvastatin amide, DZ1-Simvastatin ester, DZ1-Cisplatin ester, and DZ1-Cisplatin amide, DZ1-Artemisinin ester, and DZ1-Artemisinin amide. Furthermore, the present invention relates to improved TKI treatment of cancers by sensitizing tumor, cancer or pre-cancerous cells, in particular cancers that develop TKI resistance, including e.g. lung cancer and pancreatic cancer.

Abstract: A method and device for detecting circulating abnormal cells. The method for detecting the circulating abnormal cells comprises: respectively segmenting and labelling, by using an image processing algorithm and a morphological algorithm, cell nuclei included in dark field microscope images of a plurality of probe channels (101); inputting the dark field microscope images, in which cell nuclei are labelled, of the plurality of probe channels into a pre-built circulating abnormal cell detection model to acquire the number of staining signals included in each labelled cell nucleus in the dark field microscope image of each probe channel (102); and for each labelled cell nucleus, on the basis of the number of the staining signals included in the labelled cell nucleus in the acquired dark field microscope image of each probe channel, determining whether the labelled cell nucleus belongs to a circulating abnormal cell (103).

Abstract: An electronic substrate and an electronic device are provided. The electronic substrate includes a base substrate, and a first signal line and a second signal line on the base substrate; the electronic substrate includes a first functional region and a peripheral region, and the first signal line and the second signal line are in the peripheral region; at least one of the first signal line and the second signal line is configured to transmit an electrical signal for the first functional region; in a direction perpendicular to the base substrate, the first signal line partially overlaps with the second signal line in an overlapping region; and the first signal line includes a first wiring portion in the overlapping region and a second wiring portion outside the overlapping region, and a line width of the first wiring portion is different from a line width of the second wiring portion.

Abstract: Methods and apparatus of enhanced counting schemes for candidates of enhanced PDCCH are disclosed. The method includes: counting, by a processor, candidates of PDCCH that are to be transmitted with a plurality of transmissions, based on a candidate counting scheme, wherein the candidates are linked with one another for transmissions of the PDCCH; generating, by the processor, configuration signaling of one or more search space sets for monitoring transmissions of the PDCCH; and transmitting, by a transmitter, the configuration signaling and the candidates of the PDCCH.

Abstract: A coil unit decoupling device and a magnetic resonance system. The device comprises a first phase shift circuit, a second phase shift circuit and a first crossover element, and the first crossover element is a capacitor or inductor, wherein a first connecting end of the first phase shift circuit is connected with a first port of a first coil unit, a second connecting end of the first phase shift circuit is connected with a first connecting end of the first crossover element, a first connecting end of the second phase shift circuit is connected with a first port of a second coil unit, a second connecting end of the second phase shift circuit is connected with a second connecting end of the first crossover element, and the first coil unit and the second coil unit are located in a magnetic resonance system.

Abstract: Disclosed are methods for an uplink signal transmission. One embodiment of the subject application provides a method performed by a UE, including determining a spatial relation for a Physical Uplink Shared Channel transmission scheduled by Downlink Control Information format 0_0 in response to that a Physical Uplink Control Channel resource with the lowest Identification among at least one PUCCH resource configured in an active uplink bandwidth part of a serving cell is activated with at least two spatial relations, and performing the PUSCH transmission at least according to the spatial relation with a transmission power calculated based on a pathloss reference signal. Related apparatuses are also disclosed.

Abstract: The disclosed technology teaches training a classifier that classifies a file being transferred as encrypted or not. The technology involves accessing a plurality of training sample files, each of which is accompanied by a label of encrypted or not encrypted, sampling a configurable number of bytes of each respective file, generating features from the sampled bytes, including generating at least three of the following features: a chi-square randomness test; an arithmetic mean test; a serial correlation coefficient test; a Monte Carlo-Pi test; a Shannon entropy test; applying the generated features to train coefficients of a classifier algorithm to classify the sample files as encrypted or not encrypted; and saving the trained coefficients and classifier, whereby the classifier is trained to classify the sample files as encrypted or not encrypted.

Abstract: A touch control substrate, a display panel, and an electronic device.

Abstract: A touch control structure includes a plurality of touch signal lines in a peripheral area. A respective touch signal line includes a double-layer structure in a double-layer region and a single-layer structure in a single-layer region. The peripheral area includes a first sub-area on a first side, a second sub-area on a second side, a third sub-area on a third side, a fourth sub-area on a fourth side, of the touch control area. The first sub-area includes a side region, and one or more corner regions. The double-layer region and the single-layer region are in the first sub-area, the first sub-area has a first shortest width along a direction from the touch control area to the first sub-area, the first shortest width is greater than a shortest width of at least one of sub-areas of the peripheral area other than the first sub-area.

Abstract: The present application relates to a method and an apparatus for downlink transmission in physical downlink control channel. The method includes: determining at least one transmission configuration indicator (TCI) state for receiving a physical down-link shared channel (PDSCH) or an aperiodic channel state information reference signal (AP CSI-RS), wherein multiple TCI states are activated for at least one control resource set (CORESET) in active bandwidth part (BWP) in serving cell; and receiving the PDSCH or the AP CSI-RS according to the determined at least one TCI state.

Abstract: The disclosed technology teaches facilitate User and Entity Behavior Analytics (UEBA) by classifying a file being transferred as encrypted or not. The technology involves monitoring movement of a files by a user over a wide area network, detecting file encryption for the files using a trained classifier, wherein the detecting includes processing by the classifier some or all of the following features extracted from each of the files: a chi-square randomness test; an arithmetic mean test; a serial correlation coefficient test; a Monte Carlo-Pi test; and a Shannon entropy test, counting a number of the encrypted files moved by the user in a predetermined period, comparing a predetermined maximum number of encrypted files allowed in the predetermined period to the count of the encrypted files moved by the user and detecting that the user has moved more encrypted files than the predetermined maximum number, and generating an alert.

Abstract: The disclosed technology is generally directed to chatbot conversation management. In one example of the technology, a generic model associated with a first property associated with a chatbot manager is received. The generic model is generated based on machine learning. A refined model that is associated with the first property is generated based on the generic model and a first plurality of phrases. A first conversation is held between a chatbot and an end user. Upon determining that the value of the first property for the end user is not stored in the database, via the chatbot, during the first conversation, the refined model is used to dynamically ask questions to the end user to determine a value of the first property for the end user. In a second conversation between the chatbot and the end user, the value of the first property for the end user is referenced.

Abstract: An array substrate is provided. The array substrate includes a respective first anode electrically connected to a respective first light emitting element in a respective first subpixel; a respective second anode electrically connected to a respective second light emitting element in a respective second subpixel; a respective third anode electrically connected to a respective third light emitting element in a respective third subpixel; and a respective fourth anode electrically connected to a respective fourth light emitting element in a respective fourth subpixel. An orthographic projection of the respective third anode on a base substrate substantially covers an orthographic projection of the first initialization connecting line on the base substrate, and covers an orthographic projection of at least portion of the respective third voltage supply line on the base substrate.

Abstract: The invention provides methods for activating a repressed allele within an imprinting control region, thereby treating an imprinting associated disorder.

Abstract: Methods and apparatuses for MAC CE based beam failure recovery in multi-TRP scenario are disclosed. In one embodiment, a method comprises transmitting a capability report on supporting configuration of multiple BFD RS sets for a serving cell; and receiving a configuration including at least two NBI (new beam identification) RS sets and two BFI (beam failure indication) counters for the serving cell.

Abstract: A touch control structure is provided. The touch control structure includes a plurality of first touch electrodes arranged in a plurality of rows and a plurality of second touch electrodes arranged in a plurality of columns, forming a plurality of bridge intersections and a plurality of non-bridge intersections. The touch control structure at a respective one of the plurality of bridge intersections includes a respective one of a plurality of first bridges connecting two adjacent first touch electrode blocks in a respective row and a respective one of a plurality of second bridges connecting two adjacent second touch electrode blocks in a respective column. The touch control structure at a respective one of the plurality of non-bridge intersections includes a respective one of a plurality of intersection fill patterns spaced apart from the first touch electrode blocks and the second touch electrode blocks.

Abstract: The present disclosure provides a memory foam cushion body and a memory foam seat cushion. The memory foam cushion body includes a memory foam main body and supporting silicone. The memory foam main body is provided with an upper surface and a lower surface. The supporting silicone is arranged on the upper surface of the memory foam main body; the supporting silicone is provided with a through hole penetrating through an upper surface and a lower surface of the supporting silicone; and an air layer is formed between the upper surface of the supporting silicone, an inner wall of the through hole, and the upper surface of the memory foam main body.

Abstract: System and techniques for device-specific connections in an information centric network (ICN) are described herein. A device is detected on a physical interface at an ICN node. A virtual interface is created for the device on the physical interface and the virtual device is added to a forward information base (FIB) entry. Then, when an interest packet with a name that corresponds to the device is received, the interest packet is forwarded to the device through the physical interface using the virtual interface based on the FIB entry.

Abstract: The present invention discloses an electric heating thermal management system for an oil and gas transportation pipeline based on renewable energy and CO2 energy storage. It transmits the feedback data value through a data collection device arranged in the pipeline to the early warning device by the control device. After analysis and processing, the early warning device can feed back the data value to the control device and the remote operation device in two modes. Different degrees of heating amount can be generated for the oil and gas transportation pipelines at different positions in different modes. Hierarchical and distributed management control for the oil and gas transportation pipelines can be targetedly conducted in unblocked, easily blocked and blocked positions of the oil and gas transportation pipeline. The present invention couples the renewable energy electricity supply device and the CO2 energy storage device.

Abstract: A display substrate includes a base substrate, touch electrodes, and signal lines. At least some of the signal lines are electrically connected to the touch electrodes. The signal line includes a first signal line and a second signal line adjacent to each other. The first signal line and the second signal line respectively comprise a first-layer wiring and/or a second-layer wiring overlapped with each other in a direction perpendicular to the base substrate and electrically connected to each other. A line width of the first signal line is greater than a line width of the second signal line. The first-layer wiring of at least one of the first signal line or the second signal line is disconnected, and the second-layer wiring of the first signal line is continuous in a disconnected position.