Abstract: In an example, a system and method are provided for validating the sender of a message, such as an e-mail, text message, voice mail, network message, internet posting, or other electronic message. An authenticity server engine may first prescreen the message with anti-spam, anti-malware, and other filters. The screened message is then provided to the end user. If the end user deems the message suspicious, he may request additional validation. The authenticity server engine may then apply an example four-phase validation scheme, including analyzing header data for consistency with the message body, analyzing public data sources, analyzing private data sources, and receiving a result of an off-channel challenge to the sender. The server may then assign the message a sender validity confidence score.

Abstract: An environmental monitoring device that includes a switching mechanism is described. During operation of the environmental monitoring device, the switching mechanism (such as a switch) selectively electrically couples a first electrical-connection node and a second electrical-connection node. For example, using the switching mechanism, an electronic device that is electrically coupled to the first electrical-connection node may be selectively electrically coupled to a second electronic device that is electrically coupled to the second electrical-connection node. The selective electrical coupling may be based on one or more measurements of an environmental condition in an external environment that includes the environmental monitoring device. Moreover, a sensor mechanism in the environmental monitoring device may provide sensor data based on the one or more measurements.

Abstract: Chimeric peptides or fusion proteins are disclosed that include a RhoGAP activity domain and at least one specificity domain that targets a specific Rho protein. The fusion proteins can be used to inhibit any GTPase activity within a cell. The fusion proteins are particularly advantageous for the treatment of cancer. The present invention generally relates to chimeric peptides capable of regulating GTPases, and more particularly, to methods of targeting individual GTPases by using GTPase-activating proteins. Such proteins may be used for the treatment of cancers and other GTPase-related diseases. This invention relates to nucleic acid molecules and the encoded GTPase activating proteins, and variants thereof, and to the use of these molecules in the characterization, diagnosis, prevention, and treatment of cell signaling, immune, and cell proliferative disorders, particularly cancer. Disclosed herein are compounds and methods for regulating transcription of a selected gene.

Abstract: A method and system provide a magnetic transducer. An intermediate layer including multiple sublayers is provided. A trench is formed in the intermediate layer. A main pole having a bottom, a top wider than the bottom, a first side and a second side opposite to the first side is provided in the trench. An asymmetric gap is provided along the first and second sides of the main pole. The asymmetric gap terminates closer to the top of the main pole along the first side than on the second side. The asymmetric gap has a first thickness along the first side and a second thickness different from the first thickness along the second side. An asymmetric shield is provided on the asymmetric gap. The asymmetric shield includes a half side shield having a bottom between the top and the bottom of the main pole and terminating on the asymmetric gap.

Abstract: The present disclosure discloses a driving circuit for electrophoretic display, including a data line driving integrated circuit and a gate line driving integrated circuit, characterized in that the output terminal of each data line in the data line driving integrated circuit is configured with a modulation unit including a thermosensitive element, and the modulation unit adjusts the pulse width of the voltage signal outputted at the output terminal of the data line according to change of temperature to realize temperature compensation for the dielectric characteristic of the electrophoretic film of the electrophoretic display. The present disclosure also discloses an implementation method of the driving circuit and an electrophoretic display device. According to the present disclosure, the workload of the early stage experiment process of the product design can be saved, the production efficiency of the products can be improved, and the storage space of the chip can also be saved.

Abstract: Inhibitors of p67phox protein are provided herein, as well as pharmaceutical compositions and methods recited thereto.

Abstract: A subject voice is characterized and altered to mimic a target voice while maintaining the verbal message of the subject voice. Thus, the words and message are the same as in the original voice, but the voice that conveys the words and message in the altered voice is different. Audio signals corresponding to the altered voice are output, for example to an application for playback to a user, or to another application or device for subsequent playback by the user or someone else. In one embodiment, the altered voice is posted to a social network. In other embodiments, the altered voice is used by other software applications or consumer electronics applications, such as GPS guidance systems, ebook readers, voice-based intelligent personal assistants, chat applications, and/or others that use voice as an input or output.

Abstract: An apparatus for eliminating image sticking, a display device and a method for eliminating image sticking. The apparatus for eliminating image sticking comprises a Multi-Level Gate (MLG) circuit (1) and a gate driving module (2), the MLG circuit (1) is configured to receive a gate ON voltage unmodulated and output a modulated gate ON voltage according to an enable signal; the gate driving module (2) receives the gate ON voltage unmodulated and the modulated gate ON voltage outputted from the MLG circuit, and outputs one of the gate ON voltage unmodulated and the modulated gate ON voltage for each layer of gate lines among different layers of gate lines. No change in process on a panel side is required and a short period of time is taken to eliminate the image sticking. The image sticking eliminating effect is controllable because a gate signal and its falling time are controllable, and the image sticking eliminating is more flexible.

Abstract: A subject voice is characterized and altered to mimic a target voice while maintaining the verbal message of the subject voice. Thus, the words and message are the same as in the original voice, but the voice that conveys the words and message in the altered voice is different. Audio signals corresponding to the altered voice are output, for example to an application for playback to a user, or to another application or device for subsequent playback by the user or someone else. In one embodiment, the altered voice is posted to a social network. In other embodiments, the altered voice is used by other software applications or consumer electronics applications, such as GPS guidance systems, ebook readers, voice-based intelligent personal assistants, chat applications, and/or others that use voice as an input or output.

Abstract: Provided are inhibitors of Rho GTPase activation, and, in particular, compounds that inhibit RhoA activation by an RhoGEF. Also provided are related pharmaceutical compositions and methods. Also provided are methods of inhibiting Rho GTPase activation. Also provided are methods of screening for compounds that inhibit Rho GTPase activation by a RhoGEF.

Abstract: In an example, a mobile device is configured to automatically lock when a detector, such as a GPS receiver, determines that the device is in motion above a certain speed threshold, such as 10 mph. Additional detectors may be used to determine whether the device is operated by the user or by a passenger, so that intelligent decisions can be made about whether to lock the device. During the lock, certain selected apps such as a GPS navigation system or music player may be enabled, with limited controls as appropriate. In some cases, hands-free operations may be available. The mobile device may also be configured to provide an automated response to incoming calls and messages.

Abstract: The present invention relates to the technical field of the human computer interaction, more particularly to, a system and method for human computer interaction. The system for human computer interaction comprises a projection unit, a first image sensing unit, a second image sensing unit, an interface unit, an image processing unit, a projected interface processing unit, and a controlling unit. The system for human computer interaction provided by the present invention may easily project the human computer interaction interface on all kinds of planes encountered in people's daily life, to realize display of the human computer interaction interface everywhere, and improve users' experience.

Abstract: Data associated with a plurality of check-ins performed by users of a social network is received by processors where each check-in identifies a location and tags associated with the location within the social network that are used by the social network to describe the location. A mapping of tags to categories from a list of categories where each tag is mapped to a single category is accessed by the processors. One or more categories are determined by the processors for each check-in based on the mapping of tags to categories for each check-in. A single category is identified by the processors from the determined one or more categories for each check-in. Data associating each check-in is stored by the processors in association with the identified category for each check-in. Data representing the plurality of check-ins and the respective single category for each check-in is outputted for display by the processors.

Abstract: There is provided a method and apparatus for image color enhancement, wherein the method comprises the following steps: S1, collecting color components of an image, converting the color components from a RGB space into a HSV space, and obtaining parameters in the HSV space as hue, saturation, and value respectively; S2, performing gain operations selectively on the saturation and the value by judging the saturation in the HSV space; S3, converting the obtained parameters in the HSV space back into the RGB space. In the above method for image color enhancement, after the color components are converted into the HSV space, firstly, the saturation value is judged, and the gain operations are performed selectively by utilizing the gain function according to the judgment result.

Abstract: An electronic device that generates a programmed electrical characteristic is described. During operation, the electronic device generates a programmed electrical characteristic associated with a predefined identifier that specifies information about the electronic device (such as a type, a model, a brand, an operating condition of the electronic device, and/or a unique identifier of the electronic device). For example, an integrated circuit in the electronic device may have a varying power consumption based on the predefined identifier. In particular, the programmed electrical characteristic may be associated with execution of a program module by a processor, such as initialization of firmware by the processor. The resulting modulated waveform may be detected and analyzed by another electronic device to determine the predefined identifier and, thus, a device profile (with the specified information) for the electronic device.

Abstract: To increase the range of a remote controlled robot, one or more repeater devices can be used. A repeater device and method of use are described herein that can extend the range of wireless robots and/or improve the connectivity of wireless robots. A repeater device can include a transceiver, which includes both a receiver and a transmitter, and one or more antennas and can be powered by a power supply. Repeater devices can have orienting shapes and/or orienting bases and can be deployed using a repeater device dispenser.

Abstract: An environmental monitoring device that includes a switching mechanism is described. During operation of the environmental monitoring device, the switching mechanism (such as a switch) selectively electrically couples a first electrical-connection node and a second electrical-connection node. For example, using the switching mechanism, an electronic device that is electrically coupled to the first electrical-connection node may be selectively electrically coupled to a second electronic device that is electrically coupled to the second electrical-connection node. The selective electrical coupling may be based on one or more measurements of an environmental condition in an external environment that includes the environmental monitoring device. Moreover, a sensor mechanism in the environmental monitoring device may provide sensor data based on the one or more measurements.

Abstract: An environmental monitoring device that includes a switching mechanism is described. During operation of the environmental monitoring device, the switching mechanism (such as a switch) selectively electrically couples a first electrical-connection node and a second electrical-connection node. For example, using the switching mechanism, an electronic device that is electrically coupled to the first electrical-connection node may be selectively electrically coupled to a second electronic device that is electrically coupled to the second electrical-connection node. The selective electrical coupling may be based on one or more measurements of an environmental condition in an external environment that includes the environmental monitoring device. Moreover, a sensor mechanism in the environmental monitoring device may provide sensor data based on the one or more measurements.

Abstract: An environmental monitoring device that includes a switching mechanism is described. During operation of the environmental monitoring device, the switching mechanism (such as a switch) selectively electrically couples a first electrical-connection node and a second electrical-connection node. For example, using the switching mechanism, an electronic device that is electrically coupled to the first electrical-connection node may be selectively electrically coupled to a second electronic device that is electrically coupled to the second electrical-connection node. The selective electrical coupling may be based on one or more measurements of an environmental condition in an external environment that includes the environmental monitoring device. Moreover, a sensor mechanism in the environmental monitoring device may provide sensor data based on the one or more measurements.

Abstract: Methods for rapidly determining earthquake parameters of an earthquake include inputting a seismogram of the earthquake, searching concurrently in pre-established historical seismogram database and theoretical seismogram database by use of an approximate nearest neighbor search method, to find a set of seismograms similar to the input seismogram according to a preset similarity condition, and determining from the set of similar seismograms one or more seismograms matched with the input seismogram, and determining the earthquake parameters from the matched seismograms. With the present invention, it is possible to search in millions of seismograms and determine parameters for an earthquake in a few second, and thus realize rapid and even real-time estimation of earthquake parameters.