Patents by Inventor Yibang Chen

Yibang Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptides and other small molecules derived from regions of interacting proteins and uses thereof
    Publication number: 20030157644
    Abstract: The present invention relates generally to the field of peptides and other small molecules (i.e. peptide mimetics) as pharmaceutical and/or therapeutic agents, and to methods for identification and design of peptides and peptide mimetics having desired functional activities. Specifically, peptides and other small molecules derived from regions of interacting intracellular signaling proteins are provided. More specifically, peptides and other small molecules derived from regions of the G&bgr; subunit of heterotrimeric GTP binding proteins are provided. Such molecules include specific agonists and antagonists of G&bgr; downstream effectors, including adenylyl cyclase and phospholipase C. Such molecules are targeted to predicted regions of interaction between intracellular signaling proteins and tested for activity in functional assays using methods of the invention.
    Type: Application
    Filed: December 16, 2002
    Publication date: August 21, 2003
    Applicant: Mount Sinai School of Medicine of the City University of New York
    Inventors: Srinivas Ravi V. Iyengar, Gezhi Weng, Yibang Chen, Harel Weinstein, Elizabeth Buck
  • Peptides and other small molecules derived from regions of interacting proteins and uses thereof
    Patent number: 6555522
    Abstract: The present invention relates generally to the field of peptides and other small molecules (i.e. peptide mimetics) as pharmaceutical and/or therapeutic agents, and to methods for identification and design of peptides and peptide mimetics having desired functional activities. Specifically, peptides and other small molecules derived from regions of interacting intracellular signaling proteins are provided. More specifically, peptides and other small molecules derived from regions of the G&bgr; subunit of heterotrimeric GTP binding proteins are provided. Such molecules include specific agonists and antagonists of G&bgr; downstream effectors, including adenylyl cyclase and phospholipase C. Such molecules are targeted to predicted regions of interaction between intracellular signaling proteins and tested for activity in functional assays using methods of the invention.
    Type: Grant
    Filed: February 5, 1999
    Date of Patent: April 29, 2003
    Assignee: Mount Sinai School of Medicine of the City of New York
    Inventors: Srinivas Ravi V. Iyengar, Gezhi Weng, Yibang Chen, Harel Weinstein, Elizabeth Buck