Patents by Inventor Yibin Wang

Yibin Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TURBOMACHINE COMPRISING AN ANNULAR CASING AND A BLADED ROTOR
    Publication number: 20120201671
    Abstract: A casing treatment for a fan or compressor stage 10 of a gas turbine engine comprises circumferential grooves 16A, 16B, 16C, 16D and 16E which extend in a series disposed between the leading edges 20 and trailing edges 22 of blades 6 of a fan or compressor stage 10. The grooves 16 vary in depth d in order to optimise the stall margin of the fan or compressor stage 10 while preserving peak efficiency.
    Type: Application
    Filed: January 25, 2012
    Publication date: August 9, 2012
    Applicant: ROLLS-ROYCE PLC
    Inventors: Shahrokh SHAHPAR, Ning QIN, Yibin WANG, Greg CARNIE
  • Method for Inhibition of Phospholamban Activity for the Treatment of Cardiac Disease and Heart Failure
    Publication number: 20090149412
    Abstract: The present invention provides a method for the treatment of heart failure through the use of small peptide complexes and recombinant proteins which function to enhance contractility in failing hearts and reduce blood pressure in individuals with hypertension by inhibiting the interaction between phospholamban and sacroplasmic reticulum Ca2+ ATPase (SERCA2a) within cardiomyocytes. In addition, a means is provided for the transport of such therapeutic agents into the cytoplasm and nucleus of cardiomyocytes.
    Type: Application
    Filed: October 23, 2008
    Publication date: June 11, 2009
    Inventors: KENNETH CHIEN, WOLFGANG DILLMAN, SUSUMU MINAMISAWA, HUAPING HE, MASAHIKO HOSHIJIMA, MARKUS MEYER, CHRISTOPHER SCOTT, YIBIN WANG, GREGG J. SILVERMAN
  • Method for inhibition of phospholamban activity for the treatment of cardiac disease and heart failure
    Publication number: 20040121942
    Abstract: The present invention provides a method for the treatment of heart failure through the use of small peptide complexes and recombinant proteins which function to enhance contractility in failing hearts and reduce blood pressure in individuals with hypertension by inhibiting the interaction between phospholamban and sarcoplasmic reticulum Ca2+ ATPase (SERCA2a) within cardiomyocytes. In addition, a means is provided for the transport of such therapeutic agents into the cytoplasm and nucleus of cardiomyocytes.
    Type: Application
    Filed: November 10, 2003
    Publication date: June 24, 2004
    Inventors: Kenneth Chien, Wolfgang Dillman, Susumu Minamisawa, Huaping He, Masahiko Hoshijima, Markus Meyer, Christopher Scott, Yibin Wang, Gregg J. Silverman
  • Recombinant adenovirus for tissue specific expression in heart
    Patent number: 6451594
    Abstract: The present invention relates to a human type-5 recombinant adenovirus vector for achieving cardiac restricted transcription involving utilization of the cardiomyocyte-restricted cardiac ankyrin repeat protein (CARP) promoter with inclusion of the inverted terminal repeat sequences from human adeno-associated virus (AAV). Using green fluorescent protein (GFP) as a marker gene, the recombinant adenovirus vector (Ad/CG/ITR) is shown to direct transgene expression to myocardial tissue in vivo and in vitro in mouse models.
    Type: Grant
    Filed: September 10, 1999
    Date of Patent: September 17, 2002
    Assignee: The Regents of the University of California
    Inventors: Kenneth R. Chien, Yibin Wang, Sylvia Evans