Patents by Inventor Yichen TAN

Yichen TAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR SYNTHESIZING TARGETING MOLECULES
    Publication number: 20230250053
    Abstract: The present application provides processes for synthesizing targeting molecules of Formula (I) comprising a retinoid moiety useful in the synthesis of fat-soluble compounds for targeting and enhancing activity of therapeutic molecules, including siRNA.
    Type: Application
    Filed: June 22, 2021
    Publication date: August 10, 2023
    Inventors: Zhongping Shi, Yichen Tan, Federico Lora Gonzalez, Ronald Carrasquillo-Flores, Michael J. Smith
  • PROCESS FOR PREPARING CARBAMOYLOXYMETHYL TRIAZOLE CYCLOHEXYL ACID COMPOUNDS
    Publication number: 20220298122
    Abstract: Improved methods and intermediates thereof for preparing carbamoyloxy methyl triazole cyclohexyl acid compounds are described. These compounds are useful as LPA antagonists. Formula (I).
    Type: Application
    Filed: April 14, 2020
    Publication date: September 22, 2022
    Inventors: Richard J. Fox, Carlos A. Guerrero, Michael Dummeldinger, Dimitri Skliar, Harshkumar Patel, Yichen Tan, David Thomas George
  • SYNTHETIC PROCESSES FOR THE PRODUCTION OF 1-((3S,4R)-4-(2,6-DIFLUORO-4-METHOXYPHENYL)-2-OXOPYRROLIDIN-3-YL)-3-PHENYLUREA
    Publication number: 20210395200
    Abstract: Highly efficient processes are provided for preparing key intermediates in the synthesis of compounds (I). The process are broadly applicable and can provide selected components having a variety of substituents. Some intermediates are claimed.
    Type: Application
    Filed: November 15, 2019
    Publication date: December 23, 2021
    Inventors: Adrian Ortiz, Alina Borovika, Sergei Kolotuchin, Michael R. Luzung, Jeffrey A. Nye, Yichen Tan, Serge Zaretsky, Jason J. Zhu, Martin D. Eastgate
  • SUBSTITUTED 4-AMINO-1H-IMIDAZO[4,5-c]QUINOLINE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION
    Publication number: 20210332040
    Abstract: Improved methods and intermediates thereof for preparing substituted 4-amino-1H-imidazo[4,5-c]quinoline compounds are described. These compounds are useful as NLRP3 modulators.
    Type: Application
    Filed: August 15, 2019
    Publication date: October 28, 2021
    Inventors: Sha Lou, Adrian Ortiz, Rebecca A. Green, Christopher Robert Jamison, Candice Lee Joe, Sergei Kolotuchin, Eric M. Simmons, Neil A. Strotman, Matthew W. Haley, Yichen Tan, Andrew William Glace, Dong Lin, Albert J. DelMonte, Peng Geng, Bahar Inankur, Victor W. Rosso, Mansi S. Shah
  • Methods of producing an HIV maturation inhibitor
    Patent number: 10221208
    Abstract: A method for producing HIV maturation inhibitor compound is set forth using betulin as starting material, and utilizing Lossen rearrangement techniques.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: March 5, 2019
    Assignee: VIIV HEALTHCARE UK (NO.4) LIMITED
    Inventors: Adrian Ortiz, Maxime Soumeillant, Scott A. Savage, Neil A. Strotman, Martin D. Eastgate, Matthew W. Haley, Jeanne Ho, Jeffrey A. Nye, Zhongmin Xu, Susanne Kiau, Tamas Benkovics, Yichen Tan
  • METHODS OF PRODUCING AN HIV MATURATION INHIBITOR
    Publication number: 20180072691
    Abstract: A method for producing HIV maturation inhibitor compound is set forth using betulin as starting material, and utilizing Lossen rearrangement techniques.
    Type: Application
    Filed: April 14, 2016
    Publication date: March 15, 2018
    Inventors: Adrian ORTIZ, Maxime SOUMEILLANT, Scott A. SAVAGE, Neil A. STROTMAN, Martin D. EASTGATE, Matthew W. HALEY, Jeanne HO, Jeffrey A. NYE, Zhongmin XU, Susanne KIAU, Tamas BENKOVICS, Yichen TAN