Patents by Inventor Yicheng Cao

Yicheng Cao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Generation and affinity maturation of antibody library in silico
    Publication number: 20110124528
    Abstract: The present invention provides a methodology for efficiently generating and screening protein libraries for optimized proteins with desirable biological functions, such as improved binding affinity towards biologically and/or therapeutically important target molecules. The process is carried out computationally in a high throughput manner by mining the ever-expanding databases of protein sequences of all organisms, especially human.
    Type: Application
    Filed: October 29, 2010
    Publication date: May 26, 2011
    Inventors: Peizhi Luo, Mark Hsieh, Pingyu Zhong, Caili Wang, Yicheng Cao, Shengjiang Liu
  • Generation and selection of protein library in silico
    Publication number: 20070037214
    Abstract: The present invention provides a methodology for efficiently generating and screening protein libraries for optimized proteins with desirable biological functions, such as improved binding affinity towards biologically and/or therapeutically important target molecules. The process is carried out computationally in a high throughput manner by mining the ever-expanding databases of protein sequences of all organisms, especially human.
    Type: Application
    Filed: August 10, 2006
    Publication date: February 15, 2007
    Inventors: Peizhi Luo, Mark Hsieh, Pingyu Zhong, Caili Wang, Yicheng Cao, Shengjiang Liu
  • Novel nucleic acids and polypeptides
    Publication number: 20050266423
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: November 29, 2004
    Publication date: December 1, 2005
    Applicant: NUVELO, Inc.
    Inventors: Y. Tang, Chenghua Liu, Vinod Asundi, Rui-hong Chen, Xiaohong Qian, Zhi Wang, Tom Wehrman, Jie Zhang, Ping Zhou, Yicheng Cao, Radoje Drmanac
  • Generation and selection of protein library in silico
    Publication number: 20040010376
    Abstract: The present invention provides a methodology for efficiently generating and screening protein libraries for optimized proteins with desirable biological functions, such as improved binding affinity towards biologically and/or therapeutically important target molecules. The process is carried out computationally in a high throughput manner by mining the ever-expanding databases of protein sequences of all organisms, especially human.
    Type: Application
    Filed: May 20, 2003
    Publication date: January 15, 2004
    Inventors: Peizhi Luo, Mark Hsieh, Pingyu Zhong, Caili Wang, Yicheng Cao, Shengjiang Liu
  • Generation and affinity maturation of antibody library in silico
    Publication number: 20030022240
    Abstract: The present invention provides a methodology for efficiently generating and screening protein libraries for optimized proteins with desirable biological functions, such as improved binding affinity towards biologically and/or therapeutically important target molecules. The process is carried out computationally in a high throughput manner by mining the ever-expanding databases of protein sequences of all organisms, especially human. In one embodiment, a method is provided for constructing a library of antibody sequences based on the amino acid sequence of a lead antibody.
    Type: Application
    Filed: May 20, 2002
    Publication date: January 30, 2003
    Inventors: Peizhi Luo, Mark Hsieh, Pingyu Zhong, Caili Wang, Yicheng Cao, Shengjiang Liu