Patents by Inventor Yide Jiang

Yide Jiang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for the modifying hypoxia induced gene regulation
    Publication number: 20070224596
    Abstract: This invention provides compositions and methods to identify candidate agents capable of altering the biological activity of a polypeptide encoded by a polynucleotide involved in hypoxia-related tumorigenesis. In one aspect, the biological activity is the induction of hypoxia-related gene enolase 2 or a biological equivalent thereof. In another aspect, the biological activity is the induction of a hypoxia-related gene, inducible in the absence of the von Hippel-Lindau tumor suppressor (VHL). In yet a further aspect, the biological activity is differential expression in a neoplastic cell under hypoxia. In an alternative aspect, the biological activity is induction of a gene that is inducible in the absence of VHL, but not hypoxia.
    Type: Application
    Filed: January 20, 2006
    Publication date: September 27, 2007
    Inventors: Mariana Nacht, Yide Jiang
  • Hypoxia responsive transcription enhancer element from yeast
    Patent number: 6821751
    Abstract: The present invention is directed to DNA elements that enhance cellular gene expression in response to anaerobic growth or the presence of certain inducing agents. The enhancer element may be incorporated into expression vectors and used to increase the production of recombinant proteins.
    Type: Grant
    Filed: January 10, 2002
    Date of Patent: November 23, 2004
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Mark Alan Goldberg, Michael Vasconcelles, Yide Jiang
  • Hypoxia responsive transcription enhancer element from yeast
    Publication number: 20030060439
    Abstract: The present invention is directed to DNA elements that enhance cellular gene expression in response to anaerobic growth or the presence of certain inducing agents. The enhancer element may be incorporated into expression vectors and used to increase the production of recombinant proteins.
    Type: Application
    Filed: January 10, 2002
    Publication date: March 27, 2003
    Applicant: The Brigham and Women's Hospital, Inc.
    Inventors: Mark Alan Goldberg, Michael Vasconcelles, Yide Jiang