Patents by Inventor Yidong M. Zhu

Yidong M. Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220379094
    Abstract: A delivery sheath includes an outer tubular layer and an initially folded inner tubular layer. When an implant passes therethrough, the outer tubular layer expands and the inner tubular layer unfolds into an expanded lumen diameter. The sheath may also include selectively placed longitudinal support rods that mediate friction between the inner and outer tubular layers to facilitate easy expansion, thereby reducing the push force needed to advance the implant through the sheath's lumen.
    Type: Application
    Filed: August 8, 2022
    Publication date: December 1, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Pu Zhou, Erik Bulman, Timothy A. Geiser, Michael G. Valdez, Yidong M. Zhu, Baigui Bian, Sonny Tran, Richard D. White, Thanh Huy Le, Tung T. Le, Alpana Kiran Gowdar, Yong Gao, David Delon Williams
  • Patent number: 11458015
    Abstract: Disclosed herein are designs for improved inflatable structures for use during minimally invasive cardiovascular procedures. These inflatable structures facilitate the perfusion of blood through an anatomical structure, such as a heart valve, during the cardiovascular procedure. The inflatable structures are formed of a plurality of balloons arranged radially around a central location. The plurality of balloons form a lumen through which blood flows. Each balloon of the plurality is shaped or configured to stabilize the adjacent balloons, limiting their movement relative to each other. For example, some embodiments can feature balloons with a keystone shape that limits movement of the balloons inward toward the lumen. Some implementations can also include a support coil running through the lumen. The support coil holds enables the lumen to be open to perfusion even in the early stages of balloon inflation.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: October 4, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Yidong M. Zhu, Erik Bulman, Baigui Bian, Sam Sok, Pu Zhou
  • Publication number: 20220273428
    Abstract: Disclosed herein are embodiments of a balloon shaped to have one or more enlarged regions to selectively increase expansion forces on an implant. For example, the balloon may have a central portion that is enlarged to exert more force on the center of a stent-mounted prosthetic heart valve. This overcomes the stent-mounted prosthetic heart valve's tendency to expand with flared ends. This forms a more cylindrical or barrel shaped stent frame during expansion of the balloon—reducing or eliminating the instance wherein the cylindrical stent frame has flared ends. Alternatively, the balloon may have conical flares placed to cause or enhance flared ends of the cylindrical implant to enhance its anchoring capabilities.
    Type: Application
    Filed: March 14, 2022
    Publication date: September 1, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: David Maimon, Michael R. Bialas, Mindy Lee Ann Black, Tamir S. Levi, Linda Thai, Yidong M. Zhu
  • Patent number: 11420026
    Abstract: A delivery sheath includes an outer tubular layer and an initially folded inner tubular layer. When an implant passes therethrough, the outer tubular layer expands and the inner tubular layer unfolds into an expanded lumen diameter. The sheath may also include selectively placed longitudinal support rods that mediate friction between the inner and outer tubular layers to facilitate easy expansion, thereby reducing the push force needed to advance the implant through the sheath's lumen.
    Type: Grant
    Filed: August 26, 2019
    Date of Patent: August 23, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Pu Zhou, Erik Bulman, Timothy A. Geiser, Michael G. Valdez, Yidong M. Zhu, Baigui Bian, Sonny Tran, Richard D. White, Thanh Huy Le, Tung T. Le, Alpana Kiran Gowdar, Yong Gao, David Delon Williams
  • Publication number: 20220257911
    Abstract: A balloon shoulder assembly for a transcatheter delivery device, such as a balloon catheter, is disclosed. The balloon shoulder assembly includes a proximal balloon shoulder including a proximal collar portion that extends radially outward from a proximal shaft portion, relative to a central axis of the balloon shoulder assembly and a distal balloon shoulder including a distal collar portion that extends radially outward from a distal shaft portion. Each of the proximal balloon shoulder and the distal balloon shoulder are hollow and comprise a compressible, blow molded material.
    Type: Application
    Filed: April 27, 2022
    Publication date: August 18, 2022
    Inventor: Yidong M. Zhu
  • Patent number: 11406796
    Abstract: A delivery sheath includes an outer tubular layer and an initially folded inner tubular layer. When an implant passes therethrough, the outer tubular layer expands and the inner tubular layer unfolds into an expanded lumen diameter. The sheath may also include selectively placed longitudinal support rods that mediate friction between the inner and outer tubular layers to facilitate easy expansion, thereby reducing the push force needed to advance the implant through the sheath's lumen.
    Type: Grant
    Filed: August 23, 2019
    Date of Patent: August 9, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Pu Zhou, Erik Bulman, Timothy A. Geiser, Michael G. Valdez, Yidong M. Zhu, Baigui Bian, Sonny Tran, Richard D. White, Thanh Huy Le, Tung T. Le, Alpana Kiran Gowdar, Yong Gao, David Delon Williams
  • Publication number: 20220241563
    Abstract: Inflatable devices are disclosed including a surface which has a network of polymer chains and is configured to be inflatable into a therapeutically or diagnostically useful shape, and at least one ultrashort laser pulse-formed modification in the surface. The network can, for example, include a network morphology that is substantially unchanged by modification with the ultrashort pulse laser. Ultrashort laser pulses can be laser pulses equal to or less than 1000 picoseconds in duration. Advantageously, the etching process uses a relatively low-heat laser to avoid significant heating of surrounding polymers while modifying the surface (and other structures) of the device. The process is configured so that the polymer chain morphology adjacent the modification is substantially unaffected by the low-heat laser. The resulting inflatable device has customized surface features while still retaining substantially homogenous polymer network morphology.
    Type: Application
    Filed: April 19, 2022
    Publication date: August 4, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Pu Zhou, Bin Tian, Yidong M. Zhu
  • Patent number: 11305098
    Abstract: Inflatable devices are disclosed including a surface which has a network of polymer chains and is configured to be inflatable into a therapeutically or diagnostically useful shape, and at least one ultrashort laser pulse-formed modification in the surface. The network can, for example, include a network morphology that is substantially unchanged by modification with the ultrashort pulse laser. Ultrashort laser pulses can be laser pulses equal to or less than 1000 picoseconds in duration. Advantageously, the etching process uses a relatively low-heat laser to avoid significant heating of surrounding polymers while modifying the surface (and other structures) of the device. The process is configured so that the polymer chain morphology adjacent the modification is substantially unaffected by the low-heat laser. The resulting inflatable device has customized surface features while still retaining substantially homogenous polymer network morphology.
    Type: Grant
    Filed: July 28, 2020
    Date of Patent: April 19, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Pu Zhou, Bin Tian, Yidong M. Zhu
  • Patent number: 11273036
    Abstract: Disclosed herein are embodiments of a balloon shaped to have one or more enlarged recons to selectively increase expansion forces on an implant. For example, the balloon may have a central portion that is enlarged to exert more force on the center of a stent-mounted prosthetic heart valve. This overcomes the stent-mounted prosthetic heart valve's tendency to expand with flared ends. This forms a more cylindrical or barrel shaped stent frame during expansion of the balloon—reducing or eliminating the instance wherein the cylindrical stent frame has flared ends. Alternatively, the balloon may have conical flares placed to cause or enhance flared ends of the cylindrical implant to enhance its anchoring capabilities.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: March 15, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: David Maimon, Michael R. Bialas, Mindy Lee Ann Black, Tamir S. Levi, Linda Thai, Yidong M. Zhu
  • Publication number: 20200375736
    Abstract: The methods and devices disclosed herein promote temporal control of balloon inflation patterns. The devices include a covering for a portion of the balloon that compresses the balloon portion during the inflation process. This enables the distal portion of a balloon to be inflated prior to the proximal portion of a balloon, creating a tapered shape at lower inflation pressures. This is especially useful during transvascular implantation procedures, as it prevents dislodgement of an implant mounted on the balloon. As inflation continues, pressure exerted on the balloon by the covering is overcome such that the proximal region of the balloon inflates, forming a shape with generally straighter sides than the tapered shape, thereby expanding the cardiovascular device.
    Type: Application
    Filed: August 18, 2020
    Publication date: December 3, 2020
    Applicant: Edwards Lifesciences Corporation
    Inventors: Yidong M. Zhu, Pu Zhou, Erik Bulman, Baigui Bian
  • Publication number: 20200353227
    Abstract: Inflatable devices are disclosed including a surface which has a network of polymer chains and is configured to be inflatable into a therapeutically or diagnostically useful shape, and at least one ultrashort laser pulse-formed modification in the surface. The network can, for example, include a network morphology that is substantially unchanged by modification with the ultrashort pulse laser. Ultrashort laser pulses can be laser pulses equal to or less than 1000 picoseconds in duration. Advantageously, the etching process uses a relatively low-heat laser to avoid significant heating of surrounding polymers while modifying the surface (and other structures) of the device. The process is configured so that the polymer chain morphology adjacent the modification is substantially unaffected by the low-heat laser. The resulting inflatable device has customized surface features while still retaining substantially homogenous polymer network morphology.
    Type: Application
    Filed: July 28, 2020
    Publication date: November 12, 2020
    Inventors: Pu Zhou, Bin Tian, Yidong M. Zhu
  • Publication number: 20200353221
    Abstract: A delivery sheath includes an outer tubular layer and an initially folded inner tubular layer. When an implant passes therethrough, the outer tubular layer expands and the inner tubular layer unfolds into an expanded lumen diameter. The sheath may also include selectively placed longitudinal support rods that mediate friction between the inner and outer tubular layers to facilitate easy expansion, thereby reducing the push force needed to advance the implant through the sheath's lumen.
    Type: Application
    Filed: July 23, 2020
    Publication date: November 12, 2020
    Inventors: Pu Zhou, Erik Bulman, Timothy A. Geiser, Michael G. Valdez, Yidong M. Zhu, Baigui Bian, Sonny Tran, Richard D. White, Thanh Huy Le, Tung T. Le, Alpana Kiran Gowdar
  • Patent number: 10792471
    Abstract: A delivery sheath includes an elastic outer tubular layer and an inner tubular layer having a thick wall portion integrally connected to a thin wall portion. The inner tubular layer can have a compressed or folded condition wherein the thin wall portion folds onto an outer surface of the thick wall portion under urging of the elastic outer tubular layer. When an implant passes therethrough, the outer tubular layer stretches and the inner tubular layer unfolds into an expanded lumen diameter. Once the implant passes, the outer tubular layer again urges the inner tubular layer into the compressed condition with the sheath reassuming its smaller profile. The sheath may also include selectively placed longitudinal rods that mediate friction between the inner and outer tubular layers to facilitate easy expansion and collapse, thereby reducing the push force needed to advance the implant through the sheath's lumen.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: October 6, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Pu Zhou, Erik Bulman, Timothy A. Geiser, Michael G. Valdez, Yidong M. Zhu, Baigui Bian, Sonny Tran, Richard D. White, Thanh Huy Le, Tung T. Le, Alpana Kiran Gowdar
  • Patent number: 10751176
    Abstract: The methods and devices disclosed herein promote temporal control of balloon inflation patterns. The devices include a covering for a portion of the balloon that compresses the balloon portion during the inflation process. This enables the distal portion of a balloon to be inflated prior to the proximal portion of a balloon, creating a tapered shape at lower inflation pressures. This is especially useful during transvascular implantation procedures, as it prevents dislodgement of an implant mounted on the balloon. As inflation continues, pressure exerted on the balloon by the covering is overcome such that the proximal region of the balloon inflates, forming a shape with generally straighter sides than the tapered shape, thereby expanding the cardiovascular device.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: August 25, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Yidong M. Zhu, PU Zhou, Erik Bulman, Baigui Bian
  • Patent number: 10722693
    Abstract: Inflatable devices are disclosed including a surface which has a network of polymer chains and is configured to be inflatable into a therapeutically or diagnostically useful shape, and at least one ultrashort laser pulse-formed modification in the surface. The network can, for example, include a network morphology that is substantially unchanged by modification with the ultrashort pulse laser. Ultrashort laser pulses can be laser pulses equal to or less than 1000 picoseconds in duration. Advantageously, the etching process uses a relatively low-heat laser to avoid significant heating of surrounding polymers while modifying the surface (and other structures) of the device. The process is configured so that the polymer chain morphology adjacent the modification is substantially unaffected by the low-heat laser. The resulting inflatable device has customized surface features while still retaining substantially homogenous polymer network morphology.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: July 28, 2020
    Inventors: Pu Zhou, Bin Tian, Yidong M. Zhu
  • Patent number: 10716919
    Abstract: A delivery sheath includes an outer tubular layer and an initially folded inner tubular layer. When an implant passes therethrough, the outer tubular layer expands and the inner tubular layer unfolds into an expanded lumen diameter. The sheath may also include selectively placed longitudinal support rods that mediate friction between the inner and outer tubular layers to facilitate easy expansion, thereby reducing the push force needed to advance the implant through the sheath's lumen.
    Type: Grant
    Filed: October 2, 2018
    Date of Patent: July 21, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Pu Zhou, Erik Bulman, Timothy A. Geiser, Michael G. Valdez, Yidong M. Zhu, Baigui Bian, Sonny Tran, Richard D. White, Thanh Huy Le, Tung T. Le, Alpana K. Gowdar, Yong Gao, David D. Williams
  • Publication number: 20200179116
    Abstract: Disclosed herein are designs for improved inflatable structures for use during minimally invasive cardiovascular procedures. These inflatable structures facilitate the perfusion of blood through an anatomical structure, such as a heart valve, during the cardiovascular procedure. The inflatable structures are formed of a plurality of balloons arranged radially around a central location. The plurality of balloons form a lumen through which blood flows. Each balloon of the plurality is shaped or configured to stabilize the adjacent balloons, limiting their movement relative to each other. For example, some embodiments can feature balloons with a keystone shape that limits movement of the balloons inward toward the lumen. Some implementations can also include a support coil running through the lumen. The support coil holds enables the lumen to be open to perfusion even in the early stages of balloon inflation.
    Type: Application
    Filed: February 14, 2020
    Publication date: June 11, 2020
    Inventors: Yidong M. Zhu, Erik Bulman, Baigui Bian, Sam Sok, Pu Zhou
  • Publication number: 20200108231
    Abstract: A delivery sheath includes an outer tubular layer and an initially folded inner tubular layer. When an implant passes therethrough, the outer tubular layer expands and the inner tubular layer unfolds into an expanded lumen diameter. The sheath may also include selectively placed longitudinal support rods that mediate friction between the inner and outer tubular layers to facilitate easy expansion, thereby reducing the push force needed to advance the implant through the sheath's lumen.
    Type: Application
    Filed: August 26, 2019
    Publication date: April 9, 2020
    Inventors: Pu Zhou, Erik Bulman, Timothy A. Geiser, Michael G. Valdez, Yidong M. Zhu, Baigui Bian, Sonny Tran, Richard D. White, Thanh Huy Le, Tung T. Le, Alpana Kiran Gowdar, Yong Gao, David Delon Williams
  • Patent number: 10561496
    Abstract: Disclosed herein are designs for improved inflatable structures for use during minimally invasive cardiovascular procedures. These inflatable structures facilitate the perfusion of blood through an anatomical structure, such as a heart valve, during the cardiovascular procedure. The inflatable structures are formed of a plurality of balloons arranged radially around a central location. The plurality of balloons form a lumen through which blood flows. Each balloon of the plurality is shaped or configured to stabilize the adjacent balloons, limiting their movement relative to each other. For example, some embodiments can feature balloons with a keystone shape that limits movement of the balloons inward toward the lumen. Some implementations can also include a support coil running through the lumen. The support coil holds enables the lumen to be open to perfusion even in the early stages of balloon inflation.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: February 18, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Yidong M. Zhu, Erik Bulman, Baigui Bian, Sam Sok, Pu Zhou
  • Patent number: 10537431
    Abstract: An expandable introducer sheath for passage of implant delivery catheters, such as catheters for delivery of prosthetic heart valves. The expandable sheath balances the amounts, shapes and positions of various stiff and elastic structures in the sheath to selectively program the expandability and buckling stiffness of the sheath. The expandable sheath can include, for example, an expandable tubular layer that includes alternating stiff and elastic wall portions of a single radial thickness. The combination of stiff and elastic wall portions allow for torque and push strength to advance the expandable sheath while at the same time accommodating temporary expansion. The expandable sheath can also be reinforced with a tubular layer of braided fibers or a stent structure for additional strength. Other embodiments include selective use of slots or gaps at the distal end of a stiff wall portion to enhance expandability and distribute strain.
    Type: Grant
    Filed: October 2, 2018
    Date of Patent: January 21, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Pu Zhou, Yong Gao, Erik Bulman, Baigui Bian, Yidong M. Zhu, David D. Williams, Timothy A. Geiser, Michael G. Valdez, Sonny Tran, Richard D. White, Thanh Huy Le, Tung T. Le, Alpana K. Gowdar