Patents by Inventor Yi-Fan Hsieh

Yi-Fan Hsieh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11892407
    Abstract: A detection device, including a light-emitting component, a light-detecting component, at least one reflective optical film element, and a control unit, is provided. The light-emitting component is used for providing an excitation beam, wherein a part of the excitation beam whose dominant wavelength falls within an excitation wavelength band generates a fluorescence beam after passing through a test specimen. The light-detecting component is used for receiving a part of the fluorescence beam whose dominant wavelength falls within a detection wavelength band. The control unit is coupled to the at least one reflective optical film element. The control unit controls the at least one reflective optical film element to filter out a part of a wavelength band of an incident beam. The incident beam is at least one of the excitation beam and the fluorescence beam. A detection method of the detection device is also provided.
    Type: Grant
    Filed: September 22, 2020
    Date of Patent: February 6, 2024
    Assignee: Wistron Corporation
    Inventors: Yi Fan Hsieh, Yu-Lin Chen, Yao-Tsung Chang
  • Publication number: 20230013733
    Abstract: The invention relates to a microcarrier, comprising a continuous medium of a biocompatible polymer for culturing cells and having a three-dimensional scaffold architecture delineated peripherally by a continuous outer wall, in which spherical macropores are stacked to one another and interconnected by connecting pores. The continuous outer wall is formed with exposure pores at positions where it is in contact with the macropores, through which the interior of the microcarrier may be in fluid communication with the ambient culture medium. The microcarrier herein is produced by cast-molding and, therefore, has a continuous outer wall which provides additional mechanical strength while maintaining high porosity. The microcarrier thus produced is configured in the form of a basic geometrical body. The invention further relates to a cast-molding process for producing the microcarrier.
    Type: Application
    Filed: July 13, 2021
    Publication date: January 19, 2023
    Inventors: Pan LIN, Tzu-Yuan CHAO, Guan-Chi CHEN, Yi-Fan HSIEH
  • Patent number: 11480259
    Abstract: A fluid-drive device includes a base, a fluid container, a pressing mechanism, and a rotation mechanism. The fluid container is disposed on the base. The pressing mechanism is disposed on the base, and configured to press the fluid container. The rotation mechanism is connected to the pressing mechanism. The pressing mechanism presses the fluid container by rotating the rotation mechanism. The fluid-drive device may guide the flow of the detection fluid in the fluid container in a non-contact manner to reduce the contamination of the fluid specimen and increase the reliability of the detection.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: October 25, 2022
    Assignee: WISTRON CORP.
    Inventors: Yi Fan Hsieh, Chen An Sung, Chia Liang Lai
  • Patent number: 11320377
    Abstract: A detection device includes a light emitting element, an accommodation frame, a light detector, and a movable light splitter. The light emitting element provides an excitation beam. The accommodation frame accommodates an object under test, and a portion of the excitation beam whose dominant light emitting wavelength falls within a first waveband range forms a fluorescent beam after passing through the object under test. The light detector receives a portion of the fluorescent beam whose dominant light emitting wavelength falls within a second waveband range. The movable light splitter forms a plurality of sub-beams from an incident beam. The sub-beams have respectively different dominant light emitting wavelengths and exits at different emitting angles. The incident beam is at least one of the excitation beam and the fluorescent beam.
    Type: Grant
    Filed: March 31, 2020
    Date of Patent: May 3, 2022
    Assignee: Wistron Corporation
    Inventors: Yu-Lin Chen, Yi Fan Hsieh
  • Patent number: 11183805
    Abstract: A cable-arrangement structure includes two device bodies and a cable. The two device bodies are rotatably connected relative to a rotation axis. The cable has two fixed segments and a connecting segment connecting the two fixed segments. The two fixed segments are fixedly disposed on the two device bodies respectively. The connecting segment is movably disposed surrounding the rotation axis. An electrical apparatus includes the above cable-arrangement; therein, the cable electrically connects the two device bodies. When the two device bodies rotate relatively, by the movability characteristic of the connecting segment, the cable can be free of being tensed or twisted and will not hook other components, and the electrical connection of the two device bodies can be maintained.
    Type: Grant
    Filed: March 3, 2020
    Date of Patent: November 23, 2021
    Assignee: Wistron Corporation
    Inventors: Yi-Fan Hsieh, Chen-An Sung, Chih-Chen Chang, Yao-Tsung Chang
  • Publication number: 20210349029
    Abstract: A detection device, including a light-emitting component, a light-detecting component, at least one reflective optical film element, and a control unit, is provided. The light-emitting component is used for providing an excitation beam, wherein a part of the excitation beam whose dominant wavelength falls within an excitation wavelength band generates a fluorescence beam after passing through a test specimen. The light-detecting component is used for receiving a part of the fluorescence beam whose dominant wavelength falls within a detection wavelength band. The control unit is coupled to the at least one reflective optical film element. The control unit controls the at least one reflective optical film element to filter out a part of a wavelength band of an incident beam. The incident beam is at least one of the excitation beam and the fluorescence beam. A detection method of the detection device is also provided.
    Type: Application
    Filed: September 22, 2020
    Publication date: November 11, 2021
    Applicant: Wistron Corporation
    Inventors: Yi Fan Hsieh, Yu-Lin Chen, Yao-Tsung Chang
  • Publication number: 20210223175
    Abstract: A detection device includes a light emitting element, an accommodation frame, a light detector, and a movable light splitter. The light emitting element provides an excitation beam. The accommodation frame accommodates an object under test, and a portion of the excitation beam whose dominant light emitting wavelength falls within a first waveband range forms a fluorescent beam after passing through the object under test. The light detector receives a portion of the fluorescent beam whose dominant light emitting wavelength falls within a second waveband range. The movable light splitter forms a plurality of sub-beams from an incident beam. The sub-beams have respectively different dominant light emitting wavelengths and exits at different emitting angles. The incident beam is at least one of the excitation beam and the fluorescent beam.
    Type: Application
    Filed: March 31, 2020
    Publication date: July 22, 2021
    Applicant: Wistron Corporation
    Inventors: Yu-Lin Chen, Yi Fan Hsieh
  • Patent number: 11059043
    Abstract: A microfluidic system includes a microfluidic chip including a channel layer and a fluid control layer operatively connected to the channel layer, the channel layer having one or more fluid channels. The one or more channels are configured to contain a plurality of droplets. A valve control system is provided to control flow of fluid through the one or more fluid channels in the channel layer. The microfluidic system also includes a droplet impedance detection and feedback control system operatively connected to the valve control system. The droplet impedance detection and feedback control system is configured to detect at least a position of at least one droplet in a fluid channel and to send a signal to the valve control system to operate a particular valve at a particular time based on the detected position of the at least one droplet.
    Type: Grant
    Filed: April 19, 2017
    Date of Patent: July 13, 2021
    Assignees: The Johns Hopkins University, Pioneer Hi-Bred International, Inc.
    Inventors: Tza-Huei Wang, Brant Axt, Yi-Fan Hsieh, Helena C. Zec, Aniruddha Kaushik, Kuangwen Hsieh, Yue Yun
  • Publication number: 20210143597
    Abstract: A cable-arrangement structure includes two device bodies and a cable. The two device bodies are rotatably connected relative to a rotation axis. The cable has two fixed segments and a connecting segment connecting the two fixed segments. The two fixed segments are fixedly disposed on the two device bodies respectively. The connecting segment is movably disposed surrounding the rotation axis. An electrical apparatus includes the above cable-arrangement; therein, the cable electrically connects the two device bodies. When the two device bodies rotate relatively, by the movability characteristic of the connecting segment, the cable can be free of being tensed or twisted and will not hook other components, and the electrical connection of the two device bodies can be maintained.
    Type: Application
    Filed: March 3, 2020
    Publication date: May 13, 2021
    Inventors: Yi-Fan Hsieh, Chen-An Sung, Chih-Chen Chang, Yao-Tsung Chang
  • Publication number: 20200284372
    Abstract: A fluid-drive device includes a base, a fluid container, a pressing mechanism, and a rotation mechanism. The fluid container is disposed on the base. The pressing mechanism is disposed on the base, and configured to press the fluid container. The rotation mechanism is connected to the pressing mechanism. The pressing mechanism presses the fluid container by rotating the rotation mechanism. The fluid-drive device of the present disclosure may guide the flow of the detection fluid in the fluid container in a non-contact manner to reduce the contamination of the fluid specimen and increase the reliability of the detection.
    Type: Application
    Filed: May 31, 2019
    Publication date: September 10, 2020
    Inventors: Yi Fan HSIEH, Chen An SUNG, Chia Liang LAI
  • Publication number: 20180304267
    Abstract: A microfluidic system includes a microfluidic chip including a channel layer and a fluid control layer operatively connected to the channel layer, the channel layer having one or more fluid channels. The one or more channels are configured to contain a plurality of droplets. A valve control system is provided to control flow of fluid through the one or more fluid channels in the channel layer. The microfluidic system also includes a droplet impedance detection and feedback control system operatively connected to the valve control system. The droplet impedance detection and feedback control system is configured to detect at least a position of at least one droplet in a fluid channel and to send a signal to the valve control system to operate a particular valve at a particular time based on the detected position of the at least one droplet.
    Type: Application
    Filed: April 19, 2017
    Publication date: October 25, 2018
    Applicants: The Johns Hopkins University, Pioneer Hi-Bred International, Inc.
    Inventors: Tza-Huei Wang, Brant Axt, Yi-Fan Hsieh, Helena C. Zec, Aniruddha Kaushik, Kuangwen Hsieh, Yue Yun
  • Publication number: 20180237927
    Abstract: The invention relates to methods for producing three-dimensional ordered porous microstructures. Particularly, the invention involves facilitating the self-assembling of particles, thereby forming a three-dimensional ordered microstructure composed of a close-packing of the particles. The invention further involves forming a sacrificial layer between the three-dimensional ordered microstructure and the substrate. An inverse opal material is then filled into the interstitial voids among the particles. The particles are removed after the inverse opal material is cured, thereby producing a three-dimensional ordered porous microstructure with excellent integrity and high reproducibility.
    Type: Application
    Filed: November 11, 2016
    Publication date: August 23, 2018
    Inventors: Chen-Hung LIAO, Yi-Fan HSIEH, Yu CHENG
  • Patent number: 9126201
    Abstract: The present invention provides a method and apparatus for amplifying a nucleic acid sequence by polymerase chain reaction (PCR). The method comprises placing a PCR sample in a container which is heated by only a single heat source that provides a high temperature for denaturation in the bottom of the PCR sample, while annealing and extension automatically occur in different regions of the PCR sample due to the convection induced by a temperature gradient descending from the bottom of the PCR sample to the surface of the PCR sample.
    Type: Grant
    Filed: May 4, 2012
    Date of Patent: September 8, 2015
    Assignee: MEDIGEN BIOTECHNOLOGY CORP.
    Inventors: Pei-Jer Chen, Ping-Hei Chen, Wen-Pin Chou, Yi-Fan Hsieh, Shiou-Hwei Yeh
  • Patent number: 8833548
    Abstract: An approach is provided for decreasing infection risk and simplifying operation while wearing a contact lens. A contact lens blister package comprises a body. The body has an opening and an inner space where the contact lens is housed. The contact lens has a convex surface that is corresponded to the body opposite from the opening, so that the contact lens is pushed forward to the opening by a finger and the body is turned inside out and transformed to form a protective sheath that is temporarily worn on the finger as the contact lens is placed onto the wearer's eye.
    Type: Grant
    Filed: November 30, 2012
    Date of Patent: September 16, 2014
    Inventors: Yi-Fan Hsieh, Ta-Chih Lin
  • Publication number: 20140001059
    Abstract: An approach is provided for decreasing infection risk and simplifying operation while wearing a contact lens. A contact lens blister package comprises a body. The body has an opening and an inner space where the contact lens is housed. The contact lens has a convex surface that is corresponded to the body opposite from the opening, so that the contact lens is pushed forward to the opening by a finger and the body is turned inside out and transformed to form a protective sheath that is temporarily worn on the finger as the contact lens is placed onto the wearer's eye.
    Type: Application
    Filed: November 30, 2012
    Publication date: January 2, 2014
    Inventors: Yi-Fan Hsieh, Ta-Chih Lin
  • Publication number: 20120309083
    Abstract: The present invention provides a method and apparatus for amplifying a nucleic acid sequence by polymerase chain reaction (PCR). The method comprises placing a PCR sample in a container which is heated by only a single heat source that provides a high temperature for denaturation in the bottom of the PCR sample, while annealing and extension automatically occur in different regions of the PCR sample due to the convection induced by a temperature gradient descending from the bottom of the PCR sample to the surface of the PCR sample.
    Type: Application
    Filed: May 4, 2012
    Publication date: December 6, 2012
    Inventors: Pei-Jer Chen, Ping-Hei Chen, Wen-Pin Chou, Yi-Fan Hsieh, Shiou-Hwei Yeh
  • Patent number: 8187813
    Abstract: The present invention provides a method and apparatus for amplifying a nucleic acid sequence by polymerase chain reaction (PCR). The method comprises placing a PCR sample in a container which is heated by only a single heat source that provides a high temperature for denaturation in the bottom of the PCR sample, while annealing and extension automatically occur in different regions of the PCR sample due to the convection induced by a temperature gradient descending from the bottom of the PCR sample to the surface of the PCR sample.
    Type: Grant
    Filed: January 26, 2009
    Date of Patent: May 29, 2012
    Assignee: Medigen Biotechnology Corp.
    Inventors: Pei-Jer Chen, Ping-Hei Chen, Wen-Pin Chou, Yi-Fan Hsieh, Shiou-Hwei Yeh
  • Publication number: 20090203084
    Abstract: The present invention provides a method and apparatus for amplifying a nucleic acid sequence by polymerase chain reaction (PCR). The method comprises placing a PCR sample in a container which is heated by only a single heat source that provides a high temperature for denaturation in the bottom of the PCR sample, while annealing and extension automatically occur in different regions of the PCR sample due to the convection induced by a temperature gradient descending from the bottom of the PCR sample to the surface of the PCR sample.
    Type: Application
    Filed: January 26, 2009
    Publication date: August 13, 2009
    Applicant: Medigen Biotechnology Corp.
    Inventors: PEI-JER CHEN, Ping-Hei Chen, Wen-Pin Chou, Yi-Fan Hsieh, Shiou-Hwei Yeh