Abstract: The present disclosure provides a detector substrate and a flat panel detector, the detector substrate includes a substrate base and detector pixel units on the substrate base, each detector pixel unit includes: a driver circuit; a photoelectric conversion device disposed on a side, away from the substrate base, of the driver circuit, the photoelectric conversion device including at least two photoelectric conversion structures connected in series, a bottom electrode of a first photoelectric conversion structure being electrically connected with the driver circuit, and a top electrode of an nth photoelectric conversion structure being electrically connected with a bottom electrode of an (n+1)th photoelectric conversion structure, with n being greater than or equal to 1; and a bias voltage line on a side of the photoelectric conversion device away from the substrate base, the bias voltage line being electrically connected to a top electrode of a last photoelectric conversion structure.

Abstract: RNA editing tools for use in systems designed to measure RNA in vivo and manipulate specific cell types are disclosed herein. An RNA sensor system comprising a) a single-stranded RNA (ssRNA) sensor comprising a stop codon and a payload; optionally wherein the ssRNA sensor further comprises a normalizing gene; and b) an adenosine deaminase acting on RNA (ADAR) deaminase; wherein the sensor is capable of binding to a ssRNA target to form a double-stranded RNA (dsRNA) duplex that becomes a substrate for the ADAR deaminase; wherein the substrate comprises a mispairing within the stop codon; and wherein the mispairing is editable by the ADAR deaminase, which editing can effectively remove the stop codon so as to enable translation and expression of the payload. A method of quantifying ribonucleic acid (RNA) levels using the RNA sensor system is also disclosed.

Abstract: The present disclosure provides for porous polymer materials that include an ordered array of voids separated by a polymer framework. The porous polymer material can have a recovery state where the voids are in an uncollapsed state and iridescent color, and a deformed state having voids in a collapsed state that is non-iridescent or substantially transparent. The materials can have regions of both states simultaneously. Also described are methods for fabricating a polymer material as above, as well as chromogenic sensors including the polymer material. The sensors can have hidden anti-counterfeiting patterns, hydrophobic/oleophobic properties, and chromogenic transformation can be triggered by various stimuli such as solid target compounds, light energy, and more.

Abstract: The invention provides systems and methods for a function-based computing power allocation system (FCPAS), which is a component of an Intelligent Road Infrastructure System (IRIS). The FCPAS incorporates advanced computing capabilities that effectively allocate computational power for prediction, planning, and decision making functions. Specifically, through the FCPAS, an AV can acquire additional computational resources for vehicle prediction, planning, and decision-making functions, thereby enabling safe and efficient autonomous driving. Additionally, tailored to different traffic scenarios, the FCPAS can allocate data and computational resources (including but not limited to CPU and GPU) for vehicle automation.

Abstract: A road network balanced drainage method aimed at reducing urban waterlogging is disclosed. According to the drainage demand, the existing intersection elevation is changed or the intersection elevation that meets the drainage requirement is designed and implemented in new construction so that the intersection drainage is distributed according to the desired proportion; the water flowing to the water accumulation position is transferred to reduce the waterlogging degree. Through the analysis of the depth of water accumulation in the whole road network, the method of water flow distribution at the intersection is used to make the precipitation flow evenly distributed in the whole road network. The method can be used for solving serious water accumulation of a certain road section, the balanced drainage of the whole road network, the technical transformation of existing intersections, and for the planned and designed roads. The method can effectively eliminate and prevent urban waterlogging.

Abstract: A hybrid switch circuit for coupling two circuit terminals together is disclosed. The hybrid switch circuit includes a set of bidirectional switch devices coupled between a first circuit terminal and a second circuit terminal. The hybrid switch circuit also includes a set of unidirectional switch devices that are also coupled between the first circuit terminal and the second circuit terminal. In some cases, the set of bidirectional switch devices may be implemented using bidirectional double-base bipolar junction transistors, while the set of unidirectional switch devices may be implemented using wide bandgap transistors. In response to a de-assertion of a switch signal, a control circuit may open the set of bidirectional switch devices and, after a period of time has elapsed, open the set of unidirectional switch devices.

Abstract: The present disclosure relates to aerogels (e.g., superelastic, ultralight and/or thermal super-insulating aerogels), methods for preparation of such aerogels and uses of such aerogels. For example, the methods for preparation can comprise: freezing a suspension comprising high aspect ratio microfibers; and freeze-drying the frozen suspension to obtain the aerogel.

Abstract: Double-sided double-base bipolar junction transistor, and methods of operation. One example is a method comprising conducting main load current from an upper terminal of a switch assembly, through a double-sided double-base bipolar junction transistor (DSDB-BJT) of the switch assembly, and then through a lower terminal of the switch assembly. The conducting may be by: injecting charge carriers into an upper drift region of the DSDB-BJT as the main load current flows into an upper collector-emitter of the DSDB-BJT; and simultaneously injecting charge carriers into a lower drift region of the DSDB-BJT as main load current flows out of a lower collector-emitter of the DSDB-BJT.

Abstract: The invention discloses a nonlinear feedback circuit, which includes at least one diode. The invention also discloses a low noise amplifier using the nonlinear feedback circuit. In the invention, temperature compensation is performed for the gain change of the low noise amplifier based on the negative temperature characteristics of the diode, thereby achieving gain stability. In addition, the nonlinear characteristics of the diode can also provide high-order harmonics for the low-noise amplifier, and the mutual cancellation and addition of high-order harmonics can increase the OIP3 of the low noise amplifier.

Abstract: The present invention relates to an amphiphilic material and an application thereof in preparation of a liposome, and in particular, the present invention provides an amphiphilic material, wherein the structure of the amphiphilic material is as follows. The amphiphilic material of the present invention is used for preparing drug-loaded nanoparticles to effectively enter cells such as tumor cells, thereby enhancing the therapeutic effect of the drug.

Abstract: Thin bidirectional bipolar junction transistor (BJT) devices and methods for fabricating thin bidirectional BJT devices. The method includes forming a first base region and a first emitter/collector region on a first side of a first thick semiconductor wafer. The method also includes removing a portion of the first thick semiconductor wafer to produce a first thin semiconductor wafer. The method further includes forming a second base region and a second emitter/collector region on a second side of the first thin semiconductor wafer opposite the first side. The method also includes producing a second thin semiconductor wafer. The method further includes bonding the first thin semiconductor wafer to the second thin semiconductor wafer.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer readable media for accurately, efficiently, and flexibly generating harmonized digital images utilizing a self-supervised image harmonization neural network. In particular, the disclosed systems can implement, and learn parameters for, a self-supervised image harmonization neural network to extract content from one digital image (disentangled from its appearance) and appearance from another from another digital image (disentangled from its content). For example, the disclosed systems can utilize a dual data augmentation method to generate diverse triplets for parameter learning (including input digital images, reference digital images, and pseudo ground truth digital images), via cropping a digital image with perturbations using three-dimensional color lookup tables (“LUTs”).

Abstract: Aspects of the present disclosure describe semiconductor DFB laser structures including both pumped and unpumped regions/sections wherein unpumped regions act as DBR reflector(s) while pumped regions act as DFB gratings. Semiconductor DFB laser devices according to aspects of the present disclosure include an active layer that extends the length of the device that is identical in both pumped and unpumped regions/sections.

Abstract: The present invention relates to a method for removing protein corona on the surface of nanometer particle. Specifically, the invention provides a method for removing protein corona of protein corona modified nanometer particle, the method comprises the following steps: subjecting the protein corona modified nanometer particle to ultrasound stimulation to remove the protein corona of the protein corona modified nanometer particle; the nanometer particle comprises perfluoropentane. Ultrasound stimulation can remove protein corona on the surface of nanometer particle, overcome the masking effect of the protein corona on the ligand modified on the surface of nanometer particle, and prevent the protein corona from blocking the binding of the ligand modified on the surface of nanometer particle to cell receptor.

Abstract: The present disclosure relates to systems, methods, and non-transitory computer readable media for accurately, efficiently, and flexibly generating harmonized digital images utilizing a self-supervised image harmonization neural network. In particular, the disclosed systems can implement, and learn parameters for, a self-supervised image harmonization neural network to extract content from one digital image (disentangled from its appearance) and appearance from another from another digital image (disentangled from its content). For example, the disclosed systems can utilize a dual data augmentation method to generate diverse triplets for parameter learning (including input digital images, reference digital images, and pseudo ground truth digital images), via cropping a digital image with perturbations using three-dimensional color lookup tables (“LUTs”).

Abstract: The present disclosure discloses a similar patients identification method and system based on a patient representation image. The method includes following steps: S1: building a healthcare knowledge graph: generating the healthcare knowledge graph by extracting entities and a relationship between the entities in a knowledge source; S2: building a healthcare knowledge graph space vector library; S3: building a patient's personal healthcare knowledge graph space vector data set; S4: drawing a patient's personal healthcare representation image; and S5: performing similar patients identification based on graph similarity calculation. The present disclosure builds a visual patient representation mode, so as to convert patient's healthcare data into a visual image, so that a doctor may intuitively feel a difference of different patients and similarity of similar patients.

Abstract: Described herein are examples of improved semiconductor lasers having improved facet reliability for operation at high power and high current without significant change in device performance. The semiconductor laser may include a first semiconductor layer, an active layer, a second semiconductor layer sequentially adjacent to each other and arranged on a substrate, and a contact layer. In one example, the improved semiconductor laser may have a conductive contact less than the length of the semiconductor laser cavity and/or a dielectric layer arranged on at least one of the end portions of the contact layer.

Abstract: Examples relate to systems, methods and computer programs for a microscope, and to a microscope system comprising such as system. The system for the microscope comprises one or more processors and one or more storage devices. The system is configured to obtain image data from an optical imaging sensor of the microscope. The image data comprises at least a first frame and a subsequent second frame. The system is configured to determine a plurality of points of the first frame and a corresponding plurality of points of the second frame. In some embodiments, the plurality of points are selected from a portion of the image data showing an illuminated portion of an object being shown in the image data. The system is configured to determine a plurality of offsets between the plurality of points of the first frame and the corresponding plurality of points of the second frame. In various embodiments, the system is configured to determine a group of similar offsets from the plurality of offsets.

Abstract: The present invention relates to an amphiphilic material and an application thereof in preparation of a liposome, and in particular, the present invention provides an amphiphilic material, wherein the structure of the amphiphilic material is as follows. The amphiphilic material of the present invention is used for preparing drug-loaded nanoparticles to effectively enter cells such as tumor cells, thereby enhancing the therapeutic effect of the drug.

Abstract: The present disclosure describes systems and methods for predicting adverse health events of patients. In one embodiment, a system obtains a dataset including a plurality of values for each of a plurality of health measurements. The system can obtain the dataset in real-time or substantially real-time after a patient has taken the plurality of health measurements. The system can also obtain metadata about the dataset. The metadata may include a measure of the patient's adherence or non-adherence to a testing routine. The measure of non-adherence may indicate, for example, the quantity of days in a particular time period that the patient failed to conduct the testing routine. The system can apply an algorithm to the dataset and the metadata to generate a risk score. The risk score may indicate the likelihood that the subject will experience an adverse health event.