Patents by Inventor Yigal Dov Blum

Yigal Dov Blum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230365935
    Abstract: Stabilized amorphous calcium carbonate (ACC) as a supplement of cell culture media and the cell culture medium supplements comprising stabilized ACC are provided. In particular the stabilized ACC is useful for enhancing the growth of cell and tissue cultures, gametes and embryos in vitro and particularly in microgravity.
    Type: Application
    Filed: May 23, 2023
    Publication date: November 16, 2023
    Inventors: Yosef Ben, Yigal Dov Blum, Sara NEUMAN, Orit ECKER
  • Publication number: 20220313729
    Abstract: The present invention provides methods for enhancing and improving athletic performances of both professional and non-professional athletes by administering compositions comprising stabilized amorphous calcium carbonate. The enhanced athletic performances result among others from enhanced muscle performances, enhanced recovery and endurance.
    Type: Application
    Filed: July 23, 2020
    Publication date: October 6, 2022
    Inventors: Yossi Ben, Yigal Dov Blum
  • Publication number: 20210308178
    Abstract: The present invention provides solid compositions of amorphous calcium carbonate (ACC) and a polyphosphate, bisphosphonate or pharmaceutical salts thereof as a stabilizer. Said stabilizers stabilizes the ACC and prevent crystallization to crystalline calcium carbonate (CCC) for a long period of time, even in an aqueous suspension. The invention further provides pharmaceutical composition comprising the solid ACC compositions as well their use in treating of certain diseases and conditions.
    Type: Application
    Filed: June 9, 2021
    Publication date: October 7, 2021
    Inventors: Yosef Ben, Yigal Dov Blum, Hagay Moshe, Ben Ashkenazi
  • Publication number: 20210260103
    Abstract: The present invention provides compositions comprising amorphous calcium carbonate (ACC), suitable to being administered by inhalation, and methods for their use in treating ACC-responsive diseases and conditions. Kits for preparing suspension compositions of the present invention are provided as well.
    Type: Application
    Filed: May 13, 2021
    Publication date: August 26, 2021
    Inventors: Yosef Ben, Yigal Dov Blum
  • Patent number: 11052107
    Abstract: The present invention provides solid compositions of amorphous calcium carbonate (ACC) and a polyphosphate, bisphosphonate or pharmaceutical salts thereof as a stabilizer. Said stabilizers stabilizes the ACC and prevent crystallization to crystalline calcium carbonate ((?( (?) for a long period of time, even in an aqueous suspension. The invention further provides pharmaceutical composition comprising the solid ACC compositions as well their use in treating of certain diseases and conditions.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: July 6, 2021
    Assignee: AMORPHICAL LTD.
    Inventors: Yosef Ben, Yigal Dov Blum, Hagay Moshe, Ben Ashkenazi
  • Patent number: 11033576
    Abstract: The present invention provides compositions comprising amorphous calcium carbonate (ACC), suitable to being administered by inhalation, and methods for their use in treating ACC-responsive diseases and conditions. Further provided are ACC compositions suitable for buccal or sublingual administration.
    Type: Grant
    Filed: July 15, 2020
    Date of Patent: June 15, 2021
    Assignee: AMORPHICAL LTD.
    Inventors: Yosef Ben, Yigal Dov Blum
  • Publication number: 20200345763
    Abstract: The present invention provides compositions comprising amorphous calcium carbonate (ACC), suitable to being administered by inhalation, and methods for their use in treating ACC-responsive diseases and conditions. Further provided are ACC compositions suitable for buccal or sublingual administration.
    Type: Application
    Filed: July 15, 2020
    Publication date: November 5, 2020
    Inventors: Yosef Ben, Yigal Dov Blum
  • Patent number: 10758565
    Abstract: The present invention provides compositions comprising amorphous calcium carbonate (ACC), suitable to being administered by inhalation, and methods for their use in treating ACC-responsive diseases and conditions. Further provided are ACC compositions suitable for buccal or sublingual administration.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: September 1, 2020
    Assignee: AMORPHICAL LTD.
    Inventors: Yosef Ben, Yigal Dov Blum
  • Publication number: 20180153930
    Abstract: The present invention provides compositions comprising amorphous calcium carbonate (ACC), suitable to being administered by inhalation, and methods for their use in treating ACC-responsive diseases and conditions. Further provided are ACC compositions suitable for buccal or sublingual administration.
    Type: Application
    Filed: June 2, 2016
    Publication date: June 7, 2018
    Inventors: Yosef Ben, Yigal Dov Blum
  • Publication number: 20180140631
    Abstract: The present invention provides solid compositions of amorphous calcium carbonate (ACC) and a polyphosphate, bisphosphonate or pharmaceutical salts thereof as a stabilizer. Said stabilizers stabilizes the ACC and prevent crystallization to crystalline calcium carbonate ((?((?) for a long period of time, even in an aqueous suspension. The invention further provides pharmaceutical composition comprising the solid ACC compositions as well their use in treating of certain diseases and conditions.
    Type: Application
    Filed: June 2, 2016
    Publication date: May 24, 2018
    Inventors: Yosef Ben, Yigal Dov Blum, Hagay Moshe, Ben Ashkenazi
  • Patent number: 8648136
    Abstract: Polymer-inorganic particle blends are incorporated into structures generally involving interfaces with additional materials that can be used advantageously for forming desirable devices. In some embodiments, the structures are optical structures, and the interfaces are optical interfaces. The different materials at the interface can have differences in index-of-refraction to yield desired optical properties at the interface. In some embodiments, structures are formed with periodic variations in index-of-refraction. In particular, photonic crystals can be formed. Suitable methods can be used to form the desired structures.
    Type: Grant
    Filed: October 5, 2010
    Date of Patent: February 11, 2014
    Assignee: NanoGram Corporation
    Inventors: Nobuyuki Kambe, Christian C. Honeker, Yigal Dov Blum, David Brent MacQueen
  • Publication number: 20120319053
    Abstract: Polymer-inorganic particle blends are incorporated into structures generally involving interfaces with additional materials that can be used advantageously for forming desirable devices. In some embodiments, the structures are optical structures, and the interfaces are optical interfaces. The different materials at the interface can have differences in index-of-refraction to yield desired optical properties at the interface. In some embodiments, structures are formed with periodic variations in index-of-refraction. In particular, photonic crystals can be formed. Suitable methods can be used to form the desired structures.
    Type: Application
    Filed: August 24, 2012
    Publication date: December 20, 2012
    Inventors: Nobuyuki Kambe, Christian C. Honeker, Yigal Dov Blum, David Brent MacQueen
  • Publication number: 20120107614
    Abstract: The invention provides compositions and methods useful in providing strongly bonded functional layers on substrates. In some embodiments, the invention provides functionalized substrate surfaces that have a surface property selected from smudge resistance, easy clean, oleophobic, oleophilic, hydrophobic, hydrophilic, electrostatic, sorbing, electroresponsive, charge responsive, bioinert, and bioactive. Methods for the manufacture of such coated substrates are provided. The invention finds utility, for example, in the fields of surface and ultrathin coating chemistry and chemical functionalization of surfaces. In some embodiments, the method provides surfaces having smudge resistance and easy-clean characteristics.
    Type: Application
    Filed: October 29, 2010
    Publication date: May 3, 2012
    Inventors: Yigal Dov Blum, David Brent MacQueen, David K. Hui, Songqi Liu
  • Publication number: 20110017952
    Abstract: Polymer-inorganic particle blends are incorporated into structures generally involving interfaces with additional materials that can be used advantageously for forming desirable devices. In some embodiments, the structures are optical structures, and the interfaces are optical interfaces. The different materials at the interface can have differences in index-of-refraction to yield desired optical properties at the interface. In some embodiments, structures are formed with periodic variations in index-of-refraction. In particular, photonic crystals can be formed. Suitable methods can be used to form the desired structures.
    Type: Application
    Filed: October 5, 2010
    Publication date: January 27, 2011
    Inventors: Nobuyuki Kambe, Christian C. Honeker, Yigal Dov Blum, David Brent MacQueen
  • Publication number: 20100314588
    Abstract: Inorganic particle/polymer composites are described that involve chemical bonding between the elements of the composite. In some embodiments, the composite composition includes a polymer having side groups chemically bonded to inorganic particles. Furthermore, the composite composition can include chemically bonded inorganic particles and ordered copolymers. Various electrical, optical and electro-optical devices can be formed from the composites.
    Type: Application
    Filed: August 24, 2010
    Publication date: December 16, 2010
    Inventors: Nobuyuki Kambe, Yigal Dov Blum, Benjamin Chaloner-Gill, Shivkumar Chiruvolu, Sujeet Kumar, David Brent MacQueen
  • Patent number: 7816439
    Abstract: Polymer-inorganic particle blends are incorporated into structures generally involving interfaces with additional materials that can be used advantageously for forming desirable devices. In some embodiments, the structures are optical structures, and the interfaces are optical interfaces. The different materials at the interface can have differences in index-of-refraction to yield desired optical properties at the interface. In some embodiments, structures are formed with periodic variations in index-of-refraction. In particular, photonic crystals can be formed. Suitable methods can be used to form the desired structures.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: October 19, 2010
    Assignee: NanoGram Corporation
    Inventors: Nobuyuki Kambe, Christian C. Honeker, Yigal Dov Blum, David Brent MacQueen
  • Patent number: 7792406
    Abstract: Inorganic particle/polymer composites are described that involve chemical bonding between the elements of the composite. In some embodiments, the composite composition includes a polymer having side groups chemically bonded to inorganic particles. Furthermore, the composite composition can include chemically bonded inorganic particles and ordered copolymers. Various electrical optical and electro-optical devices can be formed from the composites.
    Type: Grant
    Filed: April 4, 2005
    Date of Patent: September 7, 2010
    Assignee: NanoGram Corporation
    Inventors: Nobuyuki Kambe, Yigal Dov Blum, Benjamin Chaloner-Gill, Shivkumar Chiruvolua, Sujeet Kumar, David Brent MacQueen
  • Patent number: 6881490
    Abstract: Inorganic particle/polymer composites are described that involve chemical bonding between the elements of the composite. In some embodiments, the composite composition includes a polymer having side groups chemically bonded to inorganic particles. Furthermore, the composite composition can include chemically bonded inorganic particles and ordered copolymers. Various electrical, optical and electro-optical devices can be formed from the composites.
    Type: Grant
    Filed: April 24, 2003
    Date of Patent: April 19, 2005
    Assignee: NanoGram Corporation
    Inventors: Nobuyuki Kambe, Yigal Dov Blum, Benjamin Chaloner-Gill, Shivkumar Chiruvolu, Sujeet Kumar, David Brent MacQueen
  • Publication number: 20030207129
    Abstract: Inorganic particle/polymer composites are described that involve chemical bonding between the elements of the composite. In some embodiments, the composite composition includes a polymer having side groups chemically bonded to inorganic particles. Furthermore, the composite composition can include chemically bonded inorganic particles and ordered copolymers. Various electrical, optical and electro-optical devices can be formed from the composites.
    Type: Application
    Filed: April 24, 2003
    Publication date: November 6, 2003
    Applicant: NanoGram Corporation
    Inventors: Nobuyuki Kambe, Yigal Dov Blum, Benjamin Chaloner-Gill, Shivkumar Chiruvolua, Sujeet Kumar, David Brent MacQueen