Patents by Inventor Yige Wu

Yige Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted pyridazinone compound and use thereof
    Patent number: 11964962
    Abstract: Disclosed is a pyridazinone compound represented by Formula (I), or a pharmaceutically acceptable salt, prodrug, hydrate, solvate, polymorph, stereoisomer, or isotopic variant thereof. The compound can be used for preparation of medicinal products for treatment and/or prophylaxis of a disease or condition associated with thyroid hormone abnormalities. The compound has higher selectivity to TH?, better pharmacokinetic parameters, desired stability, and higher agonistic activity toward TH?.
    Type: Grant
    Filed: December 14, 2021
    Date of Patent: April 23, 2024
    Assignee: SHANDONG FIRST MEDICAL UNIVERSITY & SHANDONG ACADEMY OF MEDICAL SCIENCES
    Inventors: Qingqiang Yao, Weilin Xie, Véronique Plantevin Krenitsky, Bo Liu, Yan Li, Ying Zhi, Ying Li, Yanling Mu, Jingyong Sun, Haiyang Wang, Zhongyu Wu, Haijiao Chen, Tiandi Ding, Yue Wang, Haoyi Sun, Feipeng Zhang, Peng Meng, Qingxu Liu, Huajie Li, Yige Wang, Shanshan Wen
  • COMPOSITIONS AND METHODS FOR TREATING CANCER
    Publication number: 20210322405
    Abstract: The present disclosure provides for compositions and methods of treating cancer. In some embodiments, PTPN11 is targeted with and anti-PTPN11 drug, such as a Shp2 inhibitor (e.g., SHP099). In some embodiments, other upregulated, hyperphosphorylated, or hyperacetylated target proteins are inhibited or targeted.
    Type: Application
    Filed: April 15, 2021
    Publication date: October 21, 2021
    Inventors: Li Ding, Song Cao, Yige Wu, Alla Karpova, Liang-Bo Wang, Milan Chheda, Feng Chen, Ramaswamy Govindan, Albert Kim, Michael Gillette, Steven Carr, Shankha Satpathy, Tao Liu, Karin D. Rodland, Richard D. Smith