Patents by Inventor Yigong Ge

Yigong Ge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOLUBLE DOSAGE FORMS CONTAINING CEPHEM DERIVATIVES SUITABLE FOR PARENTERAL ADMINISTRATION
    Publication number: 20150196572
    Abstract: The present invention relates to new dosage forms of cephem compounds, useful for the treatment of bacterial infections. The dosage forms are stable, exhibit enhanced solubility, and are particularly well suited for, e.g., parenteral administration.
    Type: Application
    Filed: March 4, 2015
    Publication date: July 16, 2015
    Inventors: Mahendra G. Dedhiya, Yigong Ge, Chun (Vernon) Jiang
  • SOLUBLE DOSAGE FORMS CONTAINING CEPHEM DERIVATIVES SUITABLE FOR PARENTERAL ADMINISTRATION
    Publication number: 20120010180
    Abstract: The present invention relates to new dosage forms of cephem compounds, useful for the treatment of bacterial infections. The dosage forms are stable, exhibit enhanced solubility, and are particularly well suited for, e.g., parenteral administration.
    Type: Application
    Filed: September 19, 2011
    Publication date: January 12, 2012
    Applicant: FOREST LABORATORIES HOLDINGS LTD.
    Inventors: Mahendra G. Dedhiya, Yigong Ge, Chun (Vernon) Jiang
  • SOLUBLE DOSAGE FORMS CONTAINING CEPHEM DERIVATIVES SUITABLE FOR PARENTERAL ADMINISTRATION
    Publication number: 20090082326
    Abstract: The present invention relates to new dosage forms of cephem compounds, useful for the treatment of bacterial infections. The dosage forms are stable, exhibit enhanced solubility, and are particularly well suited for, e.g., parenteral administration.
    Type: Application
    Filed: September 19, 2008
    Publication date: March 26, 2009
    Applicant: Forest Laboratories Holdings Limited
    Inventors: Mahendra Dedhiya, Yigong Ge
  • Halogen-substituted thienyl compounds
    Patent number: 7498405
    Abstract: Halogen substituted thienyl compounds exhibit potential as nucleic acid (especially double stranded DNA) binders and as antibiotic compounds.
    Type: Grant
    Filed: June 2, 2006
    Date of Patent: March 3, 2009
    Assignee: GeneSoft Pharmaceuticals, Inc.
    Inventors: Yigong Ge, Matthew J. Taylor, Eldon E. Baird, Roland W. Burli, Jacob A. Kaizerman, Amanda E. Martin, Brie Cadman
  • Charged compounds comprising a nucleic acid binding moiety and uses therefor
    Patent number: 7301037
    Abstract: Charged compounds are provided that comprise one or more regions of localized positive charge, compositions comprising such compounds, methods of synthesizing such compounds, methods of screening such compounds to identify those having anti-infective activity, and methods of using such compounds to prevent or inhibit infections. These compounds, and compositions containing them, have multiple applications, including use in human and animal medicine and in agriculture.
    Type: Grant
    Filed: July 14, 2006
    Date of Patent: November 27, 2007
    Assignee: Genesoft, Inc.
    Inventors: Yigong Ge, Matthew J. Taylor, Eldon E. Baird, Heinz E. Moser, Roland W. Burli
  • Charged compounds comprising a nucleic acid binding moiety and uses therefor
    Publication number: 20070105135
    Abstract: Charged compounds are provided that comprise one or more regions of localized positive charge, compositions comprising such compounds, methods of synthesizing such compounds, methods of screening such compounds to identify those having anti-infective activity, and methods of using such compounds to prevent or inhibit infections. These compounds, and compositions containing them, have multiple applications, including use in human and animal medicine and in agriculture.
    Type: Application
    Filed: July 14, 2006
    Publication date: May 10, 2007
    Applicants: GeneSoft Pharmaceuticals, Inc., Genesoft, Inc.
    Inventors: Yigong Ge, Matthew Taylor, Eldon Baird, Heinz Moser, Roland Burli
  • Halogen-substituted thienyl compounds
    Publication number: 20060287247
    Abstract: Halogen substituted thienyl compounds exhibit potential as nucleic acid (especially double stranded DNA) binders and as antibiotic compounds.
    Type: Application
    Filed: June 2, 2006
    Publication date: December 21, 2006
    Applicant: GeneSoft Pharmaceuticals, Inc.
    Inventors: Yigong Ge, Matthew Taylor, Eldon Baird, Roland Burli, Jacob Kaizerman, Amanda Martin, Brie Cadman
  • Halogen-substitued thienyl compounds
    Patent number: 7122626
    Abstract: Halogen substituted thienyl compounds exhibit potential as nucleic acid (especially double stranded DNA) binders and as antibiotic compounds.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: October 17, 2006
    Assignee: GeneSoft Pharmceuticals, Inc.
    Inventors: Yigong Ge, Matthew J. Taylor, Eldon E. Baird, Roland W. Bürli, Jacob A. Kaizerman, Amanda E. Martin, Brie Cadman
  • Charged compounds comprising a nucleic acid binding moiety and uses therefor
    Patent number: 7078536
    Abstract: Charged compounds are provided that comprise one or more regions of localized positive charge, compositions comprising such compounds, methods of synthesizing such compounds, methods of screening such compounds to identify those having anti-infective activity, and methods of using such compounds to prevent or inhibit infections. These compounds, and compositions containing them, have multiple applications, including use in human and animal medicine and in agriculture.
    Type: Grant
    Filed: October 22, 2002
    Date of Patent: July 18, 2006
    Assignee: Genesoft Pharmaceuticals, Inc.
    Inventors: Yigong Ge, Matthew J. Taylor, Eldon E. Baird, Heinz E. Moser, Roland W. Bürli
  • Carbapenems useful in treating and preventing pulmonary infections, pharmaceutical compositions thereof and modes of administration thereof
    Publication number: 20050065141
    Abstract: The present invention provides carbapenems to treat or prevent pulmonary infections, particularly in patients with cystic fibrosis, pneumonia, ventilator associated pneumonia, bronchitis or bronchiectstasis, pharmaceutical compositions of these carbapenems and methods of administering these carbapenems to treat or prevent pulmonary infections.
    Type: Application
    Filed: August 2, 2004
    Publication date: March 24, 2005
    Inventors: Debra Odink, Paul Truex, Yigong Ge
  • Methods for producing modified nucleic acid molecules
    Patent number: 6770462
    Abstract: A method for inserting a cassette into a nucleic acid molecule to produce a modified nucleic acid molecule, e.g., a nucleic acid-cassette fusion, is described. The method involves the use of polymerase chain reaction, thereby permitting precise targeting of the desired site in the molecule, but does not require ligation. Also described is the use of this method for high throughput screening the resulting modified nucleic acid molecules.
    Type: Grant
    Filed: November 5, 2001
    Date of Patent: August 3, 2004
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham p.l.c.
    Inventors: Alison F. Chalker, David J. Holmes, Robert Dwayne Lunsford, James Yigong Ge
  • Charged compounds comprising a nucleic acid binding moiety and uses therefor
    Publication number: 20030211508
    Abstract: Charged compounds are provided that comprise one or more regions of localized positive charge, compositions comprising such compounds, methods of synthesizing such compounds, methods of screening such compounds to identify those having anti-infective activity, and methods of using such compounds to prevent or inhibit infections. These compounds, and compositions containing them, have multiple applications, including use in human and animal medicine and in agriculture.
    Type: Application
    Filed: October 22, 2002
    Publication date: November 13, 2003
    Applicant: Genesoft, Inc.
    Inventors: Yigong Ge, Matthew J. Taylor, Eldon E. Baird, Heinz E. Moser, Roland W. Burli
  • Methods of treating infection by drug resistant bacteria
    Publication number: 20030199516
    Abstract: Methods are provided for treating an infection by Gram-positive bacteria in a mammal, by administering to the mammal an effective amount of a compound that binds noncovalently in the minor groove of duplex DNA, the compound being identified by a number of DNA binding parameters and, in many instances, being a polyaromatic compound.
    Type: Application
    Filed: September 12, 2002
    Publication date: October 23, 2003
    Applicant: Genesoft, Inc.
    Inventors: Heinz E. Moser, Eldon E. Baird, Roland W. Burli, Yigong Ge, Sarah White
  • Halogen-substitued thienyl compounds
    Publication number: 20030130198
    Abstract: Halogen substituted thienyl compounds exhibit potential as nucleic acid (especially double stranded DNA) binders and as antibiotic compounds.
    Type: Application
    Filed: April 24, 2002
    Publication date: July 10, 2003
    Applicant: GeneSoft, Inc.
    Inventors: Yigong Ge, Matthew J. Taylor, Eldon E. Baird, Roland W. Burli, Jacob A. Kaizerman, Amanda E. Martin, Brie Cadman
  • Charged compounds comprising a nucleic acid binding moiety and uses therefor
    Patent number: 6555693
    Abstract: Charged compounds are provided that comprise one or more regions of localized positive charge, compositions comprising such compounds, methods of synthesizing such compounds, methods of screening such compounds to identify those having anti-infective activity, and methods of using such compounds to prevent or inhibit infections. These compounds, and compositions containing them, have multiple applications, including use in human and animal medicine and in agriculture.
    Type: Grant
    Filed: March 14, 2001
    Date of Patent: April 29, 2003
    Assignee: Genesoft, Inc.
    Inventors: Yigong Ge, Matthew J. Taylor, Eldon E. Baird, Heinz E. Moser, Roland W. Bürli
  • Charged compounds comprising a nucleic acid binding moiety and uses therefor
    Publication number: 20020065227
    Abstract: Charged compounds are provided that comprise one or more regions of localized positive charge, compositions comprising such compounds, methods of synthesizing such compounds, methods of screening such compounds to identify those having anti-infective activity, and methods of using such compounds to prevent or inhibit infections. These compounds, and compositions containing them, have multiple applications, including use in human and animal medicine and in agriculture.
    Type: Application
    Filed: March 14, 2001
    Publication date: May 30, 2002
    Inventors: Yigong Ge, Matthew J. Taylor, Eldon E. Baird, Heinz E. Moser, Roland W. Burli
  • Response regulator
    Patent number: 6294652
    Abstract: The invention provides Response regulator polypeptides and polynucleotides encoding Response regulator polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Response regulator polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 18, 2000
    Date of Patent: September 25, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Sanjoy Biswas, James Yigong Ge, David John Holmes, Karen A Ingraham, John Throup, Nicola Gail Wallis, Magdalena Zalacain
  • Response regulator
    Patent number: 6225087
    Abstract: The invention provides Response regulator polypeptides and polynucleotides encoding Response regulator polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Response regulator polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: August 25, 1998
    Date of Patent: May 1, 2001
    Assignee: Smithkline Beecham Corporation
    Inventors: Sanjoy Biswas, James Yigong Ge, David John Holmes, Karen A Ingraham, John Throup, Nicola Gail Wallis, Magdalena Zalacain
  • Sensor histidine kinase of streptococcus pneumoniae
    Patent number: 6162619
    Abstract: The invention provides Histidine kinase polypeptides and polynucleotides encoding Histidine kinase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing Histidine kinase polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 20, 1998
    Date of Patent: December 19, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Sanjoy Biswas, Alexander Bryant, Yigong Ge, David John Holmes, Karen A Ingraham, Deborah Dee Jaworski, Andrea Marra, Lisa Kathleen Shilling, John P. Throup, Min Wang, Nicola Gail Wallis, Magdalena Zalacain