Abstract: The present disclosure provides methods for preparing a liposome composition. One of the methods includes the steps of: providing precursor liposomes encapsulating platinum-based precursors; and incubating the precursor liposomes with a salt solution to convert the platinum-based precursors to platinum-based drugs to form the liposome composition. The precursor liposomes are prepared by step of: hydrating the platinum-based drugs to form the platinum-based precursors; and adding the platinum-based precursors to a lipid bilayer vehicle to form the precursor liposomes. The liposome composition prepared by the methods shows improved encapsulation efficiency and enhanced drug loading capacity.

Abstract: A medical nanoparticle includes a core, an outer lipid layer, an inner lipid layer, a photosensitizer, and a nucleic acid. The core includes a bio-degradable ionic precipitate (BIP). The inner lipid layer is between the core and the outer lipid layer. The photosensitizer is between the inner lipid layer and the outer lipid layer, and the nucleic acid is at the surface of the core.

Abstract: A microscope monitoring device includes a pedestal, a flat light source, a microscope set, an image sensor, a motion stage and a controlling circuit board. The motion stage carries the microscope set and the image sensor and moves them according to a driving signal. Responding to a trigger signal, the image sensor senses the light passing through one or more culture tank on the multiple-well plate and the microscope set so as to generate an image signal. The controlling circuit board outputs the trigger signal and the driving signal to obtain an image of cells in the multiple-well plate. A microscope monitoring system including a server and the aforementioned microscope monitoring device is also provided.

Abstract: A cancer cell detection system includes a sample holder, a laser light source, a light detector, and a determine module. The sample holder holds a cell measurement component having metal nanoparticles, and a cell sample is on the cell measurement component. The laser light source illuminates the cell sample. The light detector detects a surface enhanced Raman scattering signal of the cell sample. The determine module selectively determines if the cell sample includes a cancer cell according to a signal intensity of a valid signal in a first Raman peak and a signal intensity of a valid signal in a second Raman peak. The first Raman peak is the signal position of the ring breathing mode of adenine, and the second Raman peak is the signal position of the stretching mode of adenine.

Abstract: A light guide pipe includes: a first light guide section formed at a first end of the light guide pipe, wherein the first light guide section is straightly extended along a longitudinal axis of the light guide pipe; a second light guide section formed at a second end of the light guide pipe, wherein an outer surface of the second light guide section is a convex curved surface, an outer diameter of the second light guide section is gradually increased along a direction from the second to the first ends, and a cavity is formed at a bottom of the second light guide section; and a third light guide section formed between the first and second light guide sections, wherein an outer surface of the third light guide section is a concave curved surface, and an outer diameter of the third light guide section is gradually decreased along the direction.

Abstract: A medical nanoparticle includes a core, an outer lipid layer, an inner lipid layer, a photosensitizer, and a nucleic acid. The core includes a bio-degradable ionic precipitate (BIP). The inner lipid layer is between the core and the outer lipid layer. The photosensitizer is between the inner lipid layer and the outer lipid layer, and the nucleic acid is at the surface of the core.

Abstract: A microscope monitoring device includes a pedestal, a flat light source, a microscope set, an image sensor, a motion stage and a controlling circuit board. The motion stage carries the microscope set and the image sensor and moves them according to a driving signal. Responding to a trigger signal, the image sensor senses the light passing through one or more culture tank on the multiple-well plate and the microscope set so as to generate an image signal. The controlling circuit board outputs the trigger signal and the driving signal to obtain an image of cells in the multiple-well plate. A microscope monitoring system including a server and the aforementioned microscope monitoring device is also provided.

Abstract: An induction device for photodynamic therapy and diagnosis is used in a living body, and for activating a photochemical reaction of a photosensitive agent in the living body. The induction device comprises a transmitter, and a light irradiator implanted in the living body. The transmitter is used for emitting a radio signal to penetrate a superficial layer of the living body. When the light irradiator receives the radio signal, the light irradiator emits light by the driving signal, such that the photosensitive agent undergoes a photochemical reaction.

Abstract: An assembly apparatus includes a master body, a slave body and a connecting device connecting the master body and the slave body. The connecting device includes a first conductor, a second conductor and an isolation material configured to electrically isolate the first conductor from the second conductor, wherein the second conductor has a first plug, a second plug and a diode electrically connecting the first plug and the second plug. The master body includes a master socket configured to receive the first plug and a master light-emitting device electrically connected to the master socket. The slave body includes a slave socket configured to receive the second plug and a slave light-emitting device electrically connected to the slave socket.

Abstract: A light therapeutic device. The light therapeutic device comprises a flexible optical element capable of deforming corresponding to an affected part of a patient and providing a light of specific wavelength for treating the affected part. The flexible optical element comprises a flexible optical conductor coated with opaque material, and light is emitted from the flexible optical conductor by selectively removing the opaque material of a part of the optical conductors.

Abstract: The present invention relates to a method for treating liver cancer or oral cancer through photodynamic therapy, comprising administrating a subject in need thereof an effective amount of formula I, formula ?, formula III or formula IV, which could release reactive oxygen species to inhibit the growth of cancer cells, which comprise with formulas as described in the specification, wherein R1 is an alkyl or an aldehyde with carbon atoms no more than 2; the cancer is liver cancer or oral cancer.

Abstract: The invention relates to a new cellulase enzyme isolated from the fungus Piromyces rhizinflata and nucleic acids encoding it.