Patents by Inventor Yih-Lin Tuan

Yih-Lin Tuan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11999956
    Abstract: The present invention discloses a targeted therapy composition and a method for suppressing breast cancer cell proliferation, migration or invasion by administrating the targeted therapy composition to a subject in need thereof. The composition comprises a type 3 epithelial membrane proteins (EMP3) targeted inhibitor. The breast cancer cells are characterized by upregulation of EMP3, EGFR, HER2, HER3, HR, or downregulation of HER4 gene expression. EMP3-targeting oligonucleotide or nuclease is administrated upon the breast cancer cells so as to degrade EMP3-coding DNA or mRNA, and to suppress breast cancer cell proliferation, migration or invasion.
    Type: Grant
    Filed: September 7, 2022
    Date of Patent: June 4, 2024
    Assignee: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Nan-Haw Chow, Yi-Wen Wang, Yih-Lin Tuan, Yao-Lung Kuo
  • Publication number: 20230089224
    Abstract: The present invention discloses a targeted therapy composition and a method for suppressing breast cancer cell proliferation, migration or invasion by administrating the targeted therapy composition to a subject in need thereof. The composition comprises a type 3 epithelial membrane proteins (EMP3) targeted inhibitor. The breast cancer cells are characterized by upregulation of EMP3, EGFR, HER2, HER3, HR, or downregulation of HER4 gene expression. EMP3-targeting oligonucleotide or nuclease is administrated upon the breast cancer cells so as to degrade EMP3-coding DNA or mRNA, and to suppress breast cancer cell proliferation, migration or invasion.
    Type: Application
    Filed: September 7, 2022
    Publication date: March 23, 2023
    Inventors: Nan-Haw CHOW, Yi-Wen Wang, Yih-Lin Tuan, Yao-Lung Kuo