Patents by Inventor YIH-MEI LIN

YIH-MEI LIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and methods for producing injectable enhanced stem cell exosomes, improved exosomes and methods of use
    Patent number: 12291725
    Abstract: This disclosure pertains to a non-living biological product. Particularly, exosomes derived from stem cells can help restore heart function. According to certain embodiments, a fluid-induced shear stress mechanical stimulation process of stem cells is used to augmented quantity and quality of exosomes produced from stem cells. These exosomes serve as a therapeutic agent for the regenerative repair of diseases, such as diseased heart tissues. Therefore, compositions comprising the exosomes derived from stem cells and methods of treating a degenerative disease by administering the exosomes isolated from stem cells are also provided.
    Type: Grant
    Filed: July 12, 2023
    Date of Patent: May 6, 2025
    Assignee: The Florida International University Board of Trustees
    Inventors: Sharan Ramaswamy, Manuel Perez, Yih-Mei Lin
  • PRODUCTION OF ENHANCED STEM CELL-BASED EXOSOMES AND USES IN SCAR TISSUE PREVENTION AND TREATMENT
    Publication number: 20250073272
    Abstract: This disclosure pertains to a non-living biological product. Particularly, exosomes derived from stem cells can help prevent or reduce scar tissue growth in cardiovascular system and restore heart function. According to certain embodiments, a fluid-induced, pathological shear stress mechanical stimulation process of stem cells is used to augmented quantity and quality of exosomes produced from stem cells. These exosomes serve as a therapeutic agent for preventing or reducing scar tissue growth in cardiovascular system. Therefore, compositions comprising the exosomes derived from stem cells and methods of preventing and/or treating scar tissue growth in cardiovascular system by administering the exosomes isolated from stem cells are also provided.
    Type: Application
    Filed: August 31, 2023
    Publication date: March 6, 2025
    Applicant: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES
    Inventors: Sharan D. RAMASWAMY, Manuel Perez NEVAREZ, Asad MIRZA, Yih-Mei LIN, Amanda IBARRA, Pranavi ARMAN
  • SYSTEMS AND METHODS FOR PRODUCING INJECTABLE ENHANCED STEM CELL EXOSOMES, IMPROVED EXOSOMES AND METHODS OF USE
    Publication number: 20230348860
    Abstract: This disclosure pertains to a non-living biological product. Particularly, exosomes derived from stem cells can help restore heart function. According to certain embodiments, a fluid-induced shear stress mechanical stimulation process of stem cells is used to augmented quantity and quality of exosomes produced from stem cells. These exosomes serve as a therapeutic agent for the regenerative repair of diseases, such as diseased heart tissues. Therefore, compositions comprising the exosomes derived from stem cells and methods of treating a degenerative disease by administering the exosomes isolated from stem cells are also provided.
    Type: Application
    Filed: July 12, 2023
    Publication date: November 2, 2023
    Applicant: The Florida International University Board of Trustees
    Inventors: SHARAN RAMASWAMY, MANUEL PEREZ, YIH-MEI LIN
  • Systems and methods for producing injectable enhanced stem cell exosomes, improved exosomes and methods of use
    Patent number: 11746329
    Abstract: This disclosure pertains to a non-living biological product. Particularly, exosomes derived from stem cells can help restore heart function. According to certain embodiments, a fluid-induced shear stress mechanical stimulation process of stem cells is used to augmented quantity and quality of exosomes produced from stem cells. These exosomes serve as a therapeutic agent for the regenerative repair of diseases, such as diseased heart tissues. Therefore, compositions comprising the exosomes derived from stem cells and methods of treating a degenerative disease by administering the exosomes isolated from stem cells are also provided.
    Type: Grant
    Filed: December 11, 2020
    Date of Patent: September 5, 2023
    Assignee: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES
    Inventors: Sharan Ramaswamy, Manuel Perez, Yih-Mei Lin
  • SYSTEMS AND METHODS FOR PRODUCING INJECTABLE ENHANCED STEM CELL EXOSOMES, IMPROVED EXOSOMES AND METHODS OF USE
    Publication number: 20210180024
    Abstract: This disclosure pertains to a non-living biological product. Particularly, exosomes derived from stem cells can help restore heart function. According to certain embodiments, a fluid-induced shear stress mechanical stimulation process of stem cells is used to augmented quantity and quality of exosomes produced from stem cells. These exosomes serve as a therapeutic agent for the regenerative repair of diseases, such as diseased heart tissues. Therefore, compositions comprising the exosomes derived from stem cells and methods of treating a degenerative disease by administering the exosomes isolated from stem cells are also provided.
    Type: Application
    Filed: December 11, 2020
    Publication date: June 17, 2021
    Applicant: The Florida International University Board of Trustees
    Inventors: SHARAN RAMASWAMY, MANUEL PEREZ, YIH-MEI LIN