Patents by Inventor Yih-Shyan Lin

Yih-Shyan Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230346955
    Abstract: Disclosed herein are novel compounds for degrading Tau protein aggregates, pharmaceutical acceptable salts, enantiomers, non-enantiomers, tautomers, racemates, solvates, metabolic precursors, or prodrugs thereof. Also disclosed herein are uses of the compounds, pharmaceutical acceptable salts, enantiomers, non-enantiomers, tautomers, racemates, solvates, metabolic precursors, or prodrugs thereof in manufacture a medicament for treating a tauopathy, as well as method for aiding in the treatment of a tauopathy or treating a tauopathy in a subject.
    Type: Application
    Filed: April 28, 2023
    Publication date: November 2, 2023
    Applicant: Aprinoia Therapeutics Limited
    Inventors: Paul TEMPEST, Ming-Kuei JANG, Yih-Shyan LIN
  • Patent number: 11642413
    Abstract: Disclosed herein are novel compounds for degrading Tau protein aggregates, pharmaceutical acceptable salts, enantiomers, non-enantiomers, tautomers, racemates, solvates, metabolic precursors, or prodrugs thereof. Also disclosed herein are uses of the compounds, pharmaceutical acceptable salts, enantiomers, non-enantiomers, tautomers, racemates, solvates, metabolic precursors, or prodrugs thereof in manufacture a medicament for treating a tauopathy, as well as method for aiding in the treatment of a tauopathy or treating a tauopathy in a subject.
    Type: Grant
    Filed: March 4, 2022
    Date of Patent: May 9, 2023
    Assignee: APRINOIA THERAPEUTICS LIMITED
    Inventors: Paul Tempest, Ming-Kuei Jang, Yih-Shyan Lin
  • Publication number: 20220354835
    Abstract: Disclosed herein are novel compounds for degrading Tau protein aggregates, pharmaceutical acceptable salts, enantiomers, non-enantiomers, tautomers, racemates, solvates, metabolic precursors, or prodrugs thereof. Also disclosed herein are uses of the compounds, pharmaceutical acceptable salts, enantiomers, non-enantiomers, tautomers, racemates, solvates, metabolic precursors, or prodrugs thereof in the manufacture of a medicament for treating a tauopathy, as well as method for aiding in the treatment of a tauopathy or treating a tauopathy in a subject.
    Type: Application
    Filed: May 14, 2021
    Publication date: November 10, 2022
    Applicant: Aprinoia Therapeutics Limited
    Inventors: Ming-Kuei JANG, Paul TEMPEST, Yih-Shyan LIN
  • Publication number: 20220280650
    Abstract: The present disclosure provides compounds, compositions and methods useful for the treatment of neurodegenerative diseases, in particular synucleinopathies.
    Type: Application
    Filed: March 4, 2022
    Publication date: September 8, 2022
    Applicant: APRINOIA THERAPEUTICS LIMITED
    Inventors: Ming-Kuei JANG, Paul TEMPEST, Yih-Shyan LIN
  • Publication number: 20220267316
    Abstract: Disclosed herein are novel compounds for degrading Tau protein aggregates, pharmaceutical acceptable salts, enantiomers, non-enantiomers, tautomers, racemates, solvates, metabolic precursors, or prodrugs thereof. Also disclosed herein are uses of the compounds, pharmaceutical acceptable salts, enantiomers, non-enantiomers, tautomers, racemates, solvates, metabolic precursors, or prodrugs thereof in manufacture a medicament for treating a tauopathy, as well as method for aiding in the treatment of a tauopathy or treating a tauopathy in a subject.
    Type: Application
    Filed: March 4, 2022
    Publication date: August 25, 2022
    Applicant: Aprinoia Therapeutics Limited
    Inventors: Paul TEMPEST, Ming-Kuei JANG, Yih-Shyan LIN
  • Patent number: 11291732
    Abstract: The present disclosure provides compounds, compositions and methods useful for the treatment of neurodegenerative diseases, in particular synucleinopathies.
    Type: Grant
    Filed: May 14, 2021
    Date of Patent: April 5, 2022
    Assignee: APRINOIA THERAPEUTICS LIMITED
    Inventors: Ming-Kuei Jang, Paul Tempest, Yih-Shyan Lin
  • Patent number: 9290526
    Abstract: The present invention relates to novel compounds, compositions containing same and methods for inhibiting human farnesyl pyrophosphate synthase or for the treatment or prevention of disease conditions using said compounds;
    Type: Grant
    Filed: June 27, 2014
    Date of Patent: March 22, 2016
    Assignee: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Youla S. Tsantrizos, Joris Wim De Schutter, Yih-Shyan Lin
  • Publication number: 20150376214
    Abstract: The present invention relates to novel compounds, compositions containing same and methods for inhibiting human farnesyl pyrophosphate synthase or for the treatment or prevention of disease conditions using said compounds;
    Type: Application
    Filed: June 27, 2014
    Publication date: December 31, 2015
    Applicant: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
    Inventors: Youla S. TSANTRIZOS, Joris Wim DE SCHUTTER, Yih-Shyan LIN
  • Patent number: 8816082
    Abstract: The present invention relates to novel compounds, compositions containing same and methods for inhibiting human farnesyl pyrophosphate synthase or for the treatment or prevention of disease conditions using said compounds;
    Type: Grant
    Filed: May 27, 2011
    Date of Patent: August 26, 2014
    Assignee: The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Youla S. Tsantrizos, Joris Wim De Schutter, Yih-Shyan Lin
  • Publication number: 20130203702
    Abstract: The present invention relates to novel compounds, compositions containing same and methods for inhibiting human farnesyl pyrophosphate synthase or for the treatment or prevention of disease conditions using said compounds;
    Type: Application
    Filed: May 27, 2011
    Publication date: August 8, 2013
    Applicant: The Royal Institution for the Advancement of Learning/McGill University
    Inventors: Youla S. Tsantrizos, Joris Wim De Schutter, Yih-Shyan Lin