Patents by Inventor Yihan Wang

Yihan Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indolinones and uses thereof
    Patent number: 6960572
    Abstract: This invention relates to compounds of the general formula: in which RA, RB, RC, RD, RE, p, q and X are as defined herein, and to their preparation and use.
    Type: Grant
    Filed: June 21, 2002
    Date of Patent: November 1, 2005
    Assignee: Ariad Pharmaceuticals, Inc.
    Inventors: William C. Shakespeare, Tomi K. Sawyer, Chester A. Metcalf, III, Yihan Wang, Regine Bohacek
  • Novel perines
    Publication number: 20050096298
    Abstract: Novel purines and uses of these compounds for the treatment of bone related disorders and cancer is disclosed.
    Type: Application
    Filed: November 22, 2004
    Publication date: May 5, 2005
    Inventors: Chester Metcalf, Manfred Weigele, Tomi Sawyer, Regine Bohacek, William Shakespeare, Rajeswari Sundaramoorthi, Yihan Wang, David Dalgarno
  • Phenylamino-pyrimidines and uses thereof
    Patent number: 6878697
    Abstract: This invention relates to compounds of the general formula: in which RA, RB, RC, RD, w, x, y, and z are as defined herein, and to their preparation and use.
    Type: Grant
    Filed: June 21, 2002
    Date of Patent: April 12, 2005
    Assignee: Ariad Pharmaceuticals, Inc.
    Inventors: Chester A. Metcalf, III, William C. Shakespeare, Tomi K. Sawyer, Yihan Wang, Regine Bohacek
  • Substituted purine derivatives
    Publication number: 20050065171
    Abstract: This invention relates to compounds of the general formula: in which Y, RA, RC and R6 are as defined herein, and to their preparation and use.
    Type: Application
    Filed: June 24, 2004
    Publication date: March 24, 2005
    Inventors: William Shakespeare, Chester Metcalf, Tomi Sawyer, Yihan Wang, Rajeswari Sundaramoorthi, David Dalgarno, Regine Bohacek, Manfred Weigele
  • Phosphorus-containing compounds and uses thereof
    Publication number: 20050032825
    Abstract: This invention concerns a new family of phosphorus-containing compounds containing a moiety JQA— in which: A is absent or is —O—, —S— or —NR2—; Q is absent or (if A is —O—, —S— or —NR2—) Q may be —V—, —OV—, —SV—, or —NR2V—, where V is an aliphatic, heteroaliphatic, aryl, or heteroaryl moiety, such that J is linked to the cyclohexyl ring directly, through A or through VA, OVA, SVA or NR2VA; K is O or S; each occurrence of Y is independently —O—, —S—, —NR2—, or a bond linking a R5 moiety to P; each occurrence of R2 and R5 is independently an aliphatic, heteroaliphatic, aryl, or heteroaryl moiety, or H; and each occurrence of R6 is independently —PK(YR5)(YR5), —SO2(YR5) or —C(O)(YR5); so long as any R2, or R5 moiety linked directly to P is not H; wherein two R2, R5 and/or R6 moieties may be chemically linked to one another to form a ring; each occurrence of G is independently —O—, —S—, —NR2— or (M)X; each occurrence of M is independently a substituted or unsubstituted methylene moiety, and any M-M? m
    Type: Application
    Filed: June 4, 2004
    Publication date: February 10, 2005
    Inventors: Chester Metcalf, Leonard Rozamus, Yihan Wang, David Berstein
  • Phosphorus-containing macrocycles
    Publication number: 20050026868
    Abstract: This invention concerns a new family of phosphorus-containing macrocycles containing various phosphonate- and phosphonate-containing moieties.
    Type: Application
    Filed: July 12, 2004
    Publication date: February 3, 2005
    Inventors: Chester Metcalf, Leonard Rozamus, Yihan Wang
  • NOVEL PHENYLAMINO-PYRIMIDINES AND USES THEREOF
    Publication number: 20040242611
    Abstract: This invention relates to compounds of the general formula: 1
    Type: Application
    Filed: June 21, 2002
    Publication date: December 2, 2004
    Inventors: Chester A. Metcalf, William C. Shakespeare, Tomi K. Sawyer, Yihan Wang, Regine Bohacek
  • Novel quinolinones and uses thereof
    Publication number: 20040167101
    Abstract: The invention relates to compounds of the general formula (and pharmaceutically acceptable derivatives thereof): 1
    Type: Application
    Filed: November 17, 2003
    Publication date: August 26, 2004
    Inventors: Chester A. Metcalf, William C. Shakespeare, Tomi K. Sawyer, Yihan Wang, Regine Bohacek, Rajeswari Sundaramoorthi
  • Novel quinolines and uses thereof
    Publication number: 20040152671
    Abstract: This invention relates to compounds of the general formula: 1
    Type: Application
    Filed: November 17, 2003
    Publication date: August 5, 2004
    Applicant: ARIAD Pharmaceuticals, Inc.
    Inventors: Yihan Wang, Chester A. Metcalf, William C. Shakespeare, Tomi K. Sawyer, Regine Bohacek, Rajeswari Sundaramoorthi
  • Phosphorus-containing compounds and uses thereof
    Publication number: 20040073024
    Abstract: This invention concerns a new family of phosphorus-containing compounds containing a moiety JQA- in which:
    Type: Application
    Filed: August 6, 2003
    Publication date: April 15, 2004
    Inventors: Chester A. Metcalf, Leonard W. Rozamus, Yihan Wang, David L. Berstein
  • Quinolinones and uses thereof
    Patent number: 6713462
    Abstract: The invention relates to compounds of the general formula (and pharmaceutically acceptable derivatives thereof): in which RA, RB, RC, RD, R5, R7, R9, R9a, AK, p, q, r and X are as defined herein, and to their preparation and use.
    Type: Grant
    Filed: June 21, 2002
    Date of Patent: March 30, 2004
    Assignee: Ariad Pharmaceuticals, Inc.
    Inventors: Chester A. Metcalf, III, William C. Shakespeare, Tomi K. Sawyer, Yihan Wang, Regine Bohacek, Rajeswari Sundaramoorthi
  • Quinolines and uses thereof
    Patent number: 6706699
    Abstract: This invention relates to compounds of the general formula: in which RA, RB, RC and RD are as defined herein, and to their preparation and use.
    Type: Grant
    Filed: June 21, 2002
    Date of Patent: March 16, 2004
    Assignee: Ariad Pharmaceuticals, Inc.
    Inventors: Yihan Wang, Chester A. Metcalf, III, William C. Shakespeare, Tomi K. Sawyer, Regine Bohacek, Rajeswari Sundaramoorthi
  • Peptide analogues and uses thereof
    Publication number: 20040002479
    Abstract: This invention relates to compounds of the general formula: 1
    Type: Application
    Filed: March 12, 2003
    Publication date: January 1, 2004
    Inventors: Yihan Wang, Tomi K. Sawyer, David L. Berstein
  • Phosphorus-containing compounds and uses thereof
    Publication number: 20030220297
    Abstract: This invention concerns a new family of phosphorus-containing compounds containing a moiety JQA—in which:
    Type: Application
    Filed: February 3, 2003
    Publication date: November 27, 2003
    Inventors: David L. Berstein, Chester A. Metcalf, Leonard W. Rozamus, Yihan Wang
  • Novel indolinones and uses thereof
    Publication number: 20030130234
    Abstract: This invention relates to compounds of the general formula: 1
    Type: Application
    Filed: June 21, 2002
    Publication date: July 10, 2003
    Inventors: William C. Shakespeare, Tomi K. Sawyer, Chester A. Metcalf, Yihan Wang, Regine Bohacek
  • Novel quinolinones and uses thereof
    Publication number: 20030114486
    Abstract: The invention relates to compounds of the general formula (and pharmaceutically acceptable derivatives thereof): 1
    Type: Application
    Filed: June 21, 2002
    Publication date: June 19, 2003
    Inventors: Chester A. Metcalf, William C. Shakespeare, Tomi K. Sawyer, Yihan Wang, Regine Bohacek
  • Novel pyrazolo- and pyrrolo-pyrimidines and uses thereof
    Publication number: 20030114467
    Abstract: The invention relates to compounds of the general formula: 1
    Type: Application
    Filed: June 21, 2002
    Publication date: June 19, 2003
    Inventors: William C. Shakespeare, Tomi K. Sawyer, Chester A. Metcalf, Yihan Wang, Regine Bohacek, Rajeswari Sundaramoorthi
  • Signal transduction inhibitors, compositions containing them
    Patent number: 6576766
    Abstract: This invention concerns compounds for inhibiting intracellular signal transduction, especially intracellular signal transduction mediate by one or more molecular interactions involving a phosphotyrosine-containing protein. This invention also relates to pharmaceutic compositions containing the compounds and prophylactic and therapeutic methods involving pharmaceutical and veterinary administration of the compounds. The compounds are of formula (1) as defined herein.
    Type: Grant
    Filed: August 17, 2000
    Date of Patent: June 10, 2003
    Assignee: Ariad Pharmaceuticals, Inc.
    Inventors: Manfred Weigele, Regine Bohacek, Virginia A. Jacobsen, Karina Macek, Michael G. Yang, Noriyuki H. Kawahata, Rajeswari Sundaramoorthi, Yihan Wang, Craig S. Takeuchi, George P. Luke, Chester A. Metcalf, III, William C. Shakespeare, Tomi K. Sawyer
  • Novel quinolines and uses thereof
    Publication number: 20030105065
    Abstract: This invention relates to compounds of the general formula: 1
    Type: Application
    Filed: June 21, 2002
    Publication date: June 5, 2003
    Inventors: Yihan Wang, Chester A. Metcalf, William C. Shakespeare, Tomi K. Sawyer, Regine Bohacek
  • Novel pyridopyrimidines and uses thereof
    Publication number: 20030105115
    Abstract: This invention relates to compounds of the general formula: 1
    Type: Application
    Filed: June 21, 2002
    Publication date: June 5, 2003
    Inventors: Chester A. Metcalf, William C. Shakespeare, Tomi K. Sawyer, Yihan Wang, Regine Bohacek