Abstract: The invention relates to the treatment of cognitive impairment associated with schizophrenia (CIAS) with a specific GlyT1 inhibitor ([5-(methylsulfonyl)-2-{[(2R)-1,1,1-trifluoropropan-2-yl]oxy}phenyl]{(1R,5R)-1-[5-(trifluoromethyl)-1,2-oxazol-3-yl]-3-azabicyclo[3.1.0]hex-3-yl}methanone). A 12-week treatment in a phase 2 study showed improvement in cognitive function as measured by the MATRICS Consensus Cognitive Battery (MCCB) overall composite score.

Abstract: A detection method for detecting intake of an aerosol-forming substrate, applicable to an electronic vaporization device, includes: obtaining an air pressure value in an airflow channel of the electronic vaporization device, the airflow channel flowing vapor generated by the electronic vaporization device for ease of inhaling, the vapor being generated through vaporization of an aerosol-forming substrate in the electronic vaporization device; calculating intake of the aerosol-forming substrate according to the air pressure value; and reminding a user according to the intake, or adjusting operating parameters of the electronic vaporization device according to the intake.

Abstract: The invention relates to the treatment of cognitive impairment associated with schizophrenia (CIAS) with a specific GlyT1 inhibitor ([5-(methylsulfonyl)-2-{[(2R)-1,1,1-trifluoropropan-2-yl]oxy}phenyl]{(1R,5R)-1-[5-(trifluoromethyl)-1,2-oxazol-3-yl]-3-azabicyclo[3.1.0]hex-3-yl}methanone). A 12-week treatment in a phase 2 study showed improvement in cognitive function as measured by the MATRICS Consensus Cognitive Battery (MCCB) overall composite score.

Abstract: Described herein is a graphical intervention test development system. The graphical intervention test development system provides a graphical intervention test development environment that facilitates computer-based design of an intervention test. The graphical intervention test development environment provides a graphical user interface (GUI) and visualizations of various aspects of an intervention test therein. The graphical intervention test development environment further provides a control interface through which a user can manipulate control parameters that affect outcomes of the intervention test.

Abstract: A detection method for detecting intake of an aerosol-forming substrate, applicable to an electronic vaporization device, includes: obtaining an air pressure value in an airflow channel of the electronic vaporization device, the airflow channel flowing vapor generated by the electronic vaporization device for ease of inhaling, the vapor being generated through vaporization of an aerosol-forming substrate in the electronic vaporization device; calculating intake of the aerosol-forming substrate according to the air pressure value; and reminding a user according to the intake, or adjusting operating parameters of the electronic vaporization device according to the intake.

Abstract: The invention relates to the treatment of cognitive impairment associated with schizophrenia (CIAS) with a specific GlyT1 inhibitor ([5-(methylsulfonyl)-2-{[(2R)-1,1,1-trifluoropropan-2-yl]oxy}phenyl]{(1R,5R)-1-[5-(trifluoromethyl)-1,2-oxazol-3-yl]-3-azabicyclo[3.1.0]hex-3-yl}methanone). A 12-week treatment in a phase 2 study showed improvement in cognitive function as measured by the MATRICS Consensus Cognitive Battery (MCCB) overall composite score.