Abstract: The present invention relates to a device for printing lumen tissue construct, a method for using the same and a 3D bioprinter. Wherein, the device comprises a spray sprayhead assembly and a bioprinting platform, the spray sprayhead assembly prints a biological construct on an inner surface of a lumen tissue by the bioprinting platform. the device for printing lumen tissue construct of the present invention provides the sprayhead assembly and the bioprinting platform, and the sprayhead assembly prints the biological construct on the inner surface of the lumen tissue by the bioprinting platform, thus avoid such problems as recurrence of thrombus and restenosis of a lumen after the lumen tissue has been transplanted for a long time, thereby improving the biological reliability of the lumen tissue.

Abstract: Systems and techniques that synthesize an image with similar texture to a selected style image. A generator network is trained to synthesize texture images depending on a selection unit input. The training configures the generator network to synthesize texture images that are similar to individual style images of multiple style images based on which is selected by the selection unit input. The generator network can be configured to minimize a covariance matrix-based style loss and/or a diversity loss in synthesizing the texture images. After training the generator network, the generator network is used to synthesize texture images for selected style images. For example, this can involve receiving user input selecting a selected style image, determining the selection unit input based on the selected style image, and synthesizing texture images using the generator network with the selection unit input and noise input.

Abstract: The present invention relates to the technical field of a bioprinter, and in particular relates to a bioprinter temperature control system and a bioprinter. The bioprinter temperature control system provided by the present invention, comprises a flow channel temperature control system, for controlling a temperature of a flow channel between an outlet of a bioprinting material container of a bioprinter and a nozzle of the bioprinter, such that the temperature of the flow channel conforms to a desired temperature of a biological printing material. The temperature control system of the present invention can realize the temperature control of the biological printing material, improving the survival rate of the printing material, and ensuring the biological function of the printing material.

Abstract: The present disclosure relates to a bioprinter spray head assembly, comprising a mounting block having a passage and a spray head mounted in the passage, wherein a first flow channel is provided in the mounting block, one end of the first flow channel is provided with a port communicating with the passage; the spray head comprises an equal diameter portion away from an outlet of the passage and a reduced diameter portion close to the outlet of the passage, wherein a second flow channel is formed between the reduced diameter portion and the passage, an opening is formed between the reduced diameter portion and the port to communicate the first flow channel and the second flow channel, and the equal diameter portion is configured to occlude the port. The adjustment of the circulation area of the spray head assembly may be achieved by changing the relative positions of the reduced diameter portion and the port, so that the adjustment is convenient and easy to carry out, and there is a favorable implementability.

Abstract: The present disclosure relates to a bioprinter spray head assembly and a bioprinter, wherein the bioprinter spray head assembly comprises a spray head and an extension rod spaced from the spray head and disposed adjacent to an outlet of the spray head, wherein an elongated flow channel is provided in the extension rod to guide a fluid printing unit serving as a biological printing material in the flow channel to be orientedly sprayed. The bioprinter spray head assembly is configured such that a fluid print unit serving as a biological printing material is orientedly sprayed through the flow channel by providing an extension rod having an elongated flow channel adjacent to the outlet of the spray head. The elongated flow channel can perform an oriented sequence of the fluid printing unit, so as to reduce the possibility of clogging.

Abstract: The present disclosure relates to a bioprinter printing assembly and a bioprinter, wherein the printing assembly comprises: a support body and a rotary rod provided with a nutrient solution supply port, wherein the rotary rod is rotatably supported on the support body, a surface of the rotary rod is used for receiving bio-ink provided by a printing spray head, the rotary rod includes a hollow tube section having a central through hole, and a tube wall of the hollow tube section is provided with a permeable hole communicating with the central through hole, and the nutrient solution supply port communicates with the central through hole of the rotary rod to guide external nutrient solution into the rotary rod.

Abstract: The present invention relates to the bioprinting technical field, and in particular relates to a bioprinter and a calibration method thereof. The bioprinter provided by the present invention comprises a control device, a first detection device, and a second detection device, wherein the first detection device is capable of sending a first signal to the control device when the spray device moves to a first position along the Z-axis direction such that the control device calibrates the preset length value of the spray device, and the second detection device is capable of sending a second signal to the control device when the second detection device moves to a second position along the Z-axis direction such that the control device calibrates the preset height value of the printing material initial adhesion surface.

Abstract: The present disclosure relates to a bioprinter, which comprises a spray head, a connector and a bioprinting material container having a discharge pipe, wherein a first end of the connector is threadedly connected with the discharge pipe, and a second end of the connector is detachably connected with the spray head. The bioprinter is configured such that, a connector is provided between the discharge pipe of the bioprinting material container and the spray head, wherein the first end of the connector is threadedly connected with the discharge pipe, and the second end is detachably disposed on the spray head.

Abstract: In some embodiments, techniques for synthesizing an image style based on a plurality of neural networks are described. A computer system selects a style image based on user input that identifies the style image. The computer system generates an image based on a generator neural network and a loss neural network. The generator neural network outputs the synthesized image based on a noise vector and the style image and is trained based on style features generated from the loss neural network. The loss neural network outputs the style features based on a training image. The training image and the style image have a same resolution. The style features are generated at different resolutions of the training image. The computer system provides the synthesized image to a user device in response to the user input.

Abstract: A controller for a power steering system estimates rack force and its derivative, such as based on lateral acceleration, yaw rate, vehicle speed, or other parameters. A control torque is calculated based on the rack force, its derivative, and the vehicle speed and is summed with an input torque from the driver to determine an amount of assist torque to provide. The control torque may be a shape function that has a sign determined by the sign of the derivative and a magnitude that decreases from a maximal value with increase in the magnitude of the rack force. The maximal value may be determined according to vehicle speed.

Abstract: Systems and techniques that synthesize an image with similar texture to a selected style image. A generator network is trained to synthesize texture images depending on a selection unit input. The training configures the generator network to synthesize texture images that are similar to individual style images of multiple style images based on which is selected by the selection unit input. The generator network can be configured to minimize a covariance matrix-based style loss and/or a diversity loss in synthesizing the texture images. After training the generator network, the generator network is used to synthesize texture images for selected style images. For example, this can involve receiving user input selecting a selected style image, determining the selection unit input based on the selected style image, and synthesizing texture images using the generator network with the selection unit input and noise input.

Abstract: A controller for a power steering system estimates rack force and its derivative, such as based on lateral acceleration, yaw rate, vehicle speed, or other parameters. A control torque is calculated based on the rack force, its derivative, and the vehicle speed and is summed with an input torque from the driver to determine an amount of assist torque to provide. The control torque may be a shape function that has a sign determined by the sign of the derivative and a magnitude that decreases from a maximal value with increase in the magnitude of the rack force. The maximal value may be determined according to vehicle speed.

Abstract: This invention relates, inter alia, to detecting and/or measuring succinylacetone and one or more additional biological analytes using mass spectrometry, e.g., tandem mass spectrometry, by derivatizing succinylacetone in a sample by contacting the sample with an extraction solution comprising a C1-3 linear or branched chain monoalcohol and a strong base selected from the group consisting of hydrazine, a modified hydrazine, and hydroxylamine.

Abstract: This invention relates, inter alia, to detecting and/or measuring succinylacetone and one or more additional biological analytes using mass spectrometry.

Abstract: Methods of evaluating molecular isomers of branched-chain amino acids are featured. The methods can include: derivatizing one or more molecular isomers of branched-chain amino acids in a sample comprising a branched-chain amino acid labeled with one or more heavy atoms as a first standard; adding, to the sample, after derivatization, a nonderivatized or derivatized branched chain amino acid that is labeled with one or more heavy atoms, as a second standard; evaluating the sample using tandem mass spectrometry; and detecting peaks indicative of derivatized and nonderivatized forms of one or more branched-chain amino acids in the sample.

Abstract: This invention relates, inter alia, to detecting and/or measuring succinylacetone and one or more additional biological analytes using mass spectrometry.

Abstract: Methods of evaluating molecular isomers of branched-chain amino acids are featured. The methods can include: derivatizing one or more molecular isomers of branched-chain amino acids in a sample comprising a branched-chain amino acid labeled with one or more heavy atoms as a first standard; adding, to the sample, after derivatization, a nonderivatized or derivatized branched chain amino acid that is labeled with one or more heavy atoms, as a second standard; evaluating the sample using tandem mass spectrometry; and detecting peaks indicative of derivatized and nonderivatized forms of one or more branched-chain amino acids in the sample.

Abstract: This invention relates, inter alia, to detecting and/or measuring succinylacetone and one or more additional biological analytes using mass spectrometry.

Abstract: Methods of evaluating molecular isomers of branched-chain amino acids are featured. The methods can include: derivatizing one or more molecular isomers of branched-chain amino acids in a sample comprising a branched-chain amino acid labeled with one or more heavy atoms as a first standard; adding, to the sample, after derivatization, a nonderivatized or derivatized branched chain amino acid that is labeled with one or more heavy atoms, as a second standard; evaluating the sample using tandem mass spectrometry; and detecting peaks indicative of derivatized and nonderivatized forms of one or more branched-chain amino acids in the sample.

Abstract: This invention relates, inter alia, to detecting and/or measuring succinylacetone and one or more additional biological analytes using mass spectrometry.