Abstract: A compound as shown in formula I, or an optical isomer thereof, a solvate thereof, a pharmaceutically acceptable salt thereof, a prodrug thereof, a tautomer thereof, a mesomer thereof, a racemate thereof, an enantiomer thereof, a diastereomer thereof, a mixture form thereof, a metabolite thereof, a metabolic precursor thereof, or an isotope substitute form thereof. TB is a target recognition/binding portion, L is a linking portion, and U is a ubiquitin protease recognition/binding portion, the three portions being connected by means of chemical bonds. The compound can significantly down-regulate mutated androgen receptor (AR) proteins, and has good inhibitory activity on prostate cancer cell lines.

Abstract: The present disclosure provides a method for configuring a learning model for music generation and the corresponding learning model. The method includes training a masked autoencoder with training data comprising a combination of a reconstruction loss over time and frequency domains and a patch-based adversarial objective operating at different resolutions. An omnidirectional latent diffusion model is trained based on music data represented in a latent space to obtain a pretrained diffusion model. The pretrained diffusion model is fine-tuned based on text-guided music generation, bidirectional music in-painting, and unidirectional music continuation. The method enables high-fidelity music generation conditioned on text or music representations while maintaining computational efficiency.

Abstract: An identification method of seabed weak echoes in airborne LiDAR bathymetry and a system thereof are provided, which belong to the technical field of marine surveying and mapping. The method includes: dividing sea area laser pulses into surface-seabed pulses or seabed-undefined pulses based on preprocessed data; using two-stage local maximum method to determine potential seabed echo positions of ALB waveforms and pre-generate seabed points; defining an ellipsoid neighborhood related to density and extracting spatial features of a pre-generated point cloud; constructing a BP neural network to identify seabed points in the pre-generated point cloud, and optimizing the identification result of the seabed points based on a laser pulse echo sequence and point cloud density.

Abstract: The present disclosure relates to method for cloud-edge data transmission of an electrochemical energy storage station, including: caching the first data to be transmitted and sending a connection re-establishment request to the cloud node; sending second data to be transmitted to the cloud node; sending the cached first data to the cloud node in an idle period after the first period; determining a characteristic value of third data to be transmitted, sending the characteristic value to the cloud node, and caching a non-characteristic value apart from the characteristic value, in a case where an abnormal working condition of the edge node is detected; sending to the cloud node fourth data to be transmitted; and sending the non-characteristic value of the third data to the cloud node in an idle period after the second period.

Abstract: A leaf imaging system is disclosed which includes a leaf-handling subsystem which includes a first leaf contactor and a second leaf contactor and configured to receive a leaf in therebetween, and an encoder coupled to one of the first or second leaf contactors, the encoder configured to selectively trigger a camera corresponding to motion of the leaf. The leaf imaging system further includes a lightbox in communication with the leaf-handling subsystem and configured to provide light to the leaf as the leaf passes between the first and the second leaf contactors; and a controller in communication with the encoder, the camera, and the lightbox and configured to operate the camera based on output of the encoder.

Abstract: A method and system are disclosed for providing consistent images of leaves of plants, including articulating a lower case of a housing with respect to an upper case via an imaging chamber articulation mechanism from i) a closed state to ii) an open state, the articulable space forms an imaging chamber which is dark when the imaging chamber articulation mechanism is in the closed state, placing the leaf within the imaging chamber, articulating the imaging chamber articulation mechanism to the closed state, activating one or more light sources, actuating a linear actuator to thereby linearly move a camera from i) an initial position to ii) an end position, obtaining images from the camera, re-actuating the linear actuator to thereby linearly move the camera from the end position to the initial position, re-articulating the lower case to the open state, and removing the leaf.

Abstract: A method and system are disclosed for providing consistent images of leaves of plants, including articulating a lower case of a housing with respect to an upper case via an imaging chamber articulation mechanism from i) a closed state to ii) an open state, the articulable space forms an imaging chamber which is dark when the imaging chamber articulation mechanism is in the closed state, placing the leaf within the imaging chamber, articulating the imaging chamber articulation mechanism to the closed state, activating one or more light sources, actuating a linear actuator to thereby linearly move a camera from i) an initial position to ii) an end position, obtaining images from the camera, re-actuating the linear actuator to thereby linearly move the camera from the end position to the initial position, re-articulating the lower case to the open state, and removing the leaf.