Patents by Inventor Yike Ni

Yike Ni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MK2 inhibitors and uses thereof
    Patent number: 11584757
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: February 27, 2020
    Date of Patent: February 21, 2023
    Assignee: Celgene CAR LLC
    Inventors: Matthew David Alexander, Claudio Chuaqui, John Malona, Joseph John McDonald, Yike Ni, Deqiang Niu, Russell C. Petter, Juswinder Singh, Chittari Pabba
  • MK2 inhibitors and uses thereof
    Patent number: 11098061
    Abstract: The present invention provides compounds of formula V: or pharmaceutically acceptable salts thereof, useful as inhibitors of MK2 kinases, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: August 24, 2021
    Assignee: Celgene CAR LLC
    Inventors: Matthew David Alexander, Joseph John McDonald, Yike Ni, Deqiang Niu, Russell C. Petter, Lixin Qiao, Juswinder Singh, Tao Wang, Zhendong Zhu
  • MK2 INHIBITORS AND USES THEREOF
    Publication number: 20210053984
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Application
    Filed: February 27, 2020
    Publication date: February 25, 2021
    Inventors: Matthew David Alexander, Claudio Chuaqui, John Malona, Joseph John McDonald, Yike Ni, Deqiang Niu, Russell C. Petter, Juswinder Singh, Chittari Pabba
  • MK2 inhibitors and uses thereof
    Patent number: 10577380
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: April 4, 2019
    Date of Patent: March 3, 2020
    Assignee: Celgene CAR LLC
    Inventors: Matthew David Alexander, Claudio Chuaqui, John Malona, Joseph John McDonald, Yike Ni, Deqiang Niu, Russell C. Petter, Juswinder Singh, Chittari Pabba
  • MK2 INHIBITORS AND USES THEREOF
    Publication number: 20190375762
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Application
    Filed: April 4, 2019
    Publication date: December 12, 2019
    Inventors: Matthew David Alexander, Claudio Chuaqui, John Malona, Joseph John McDonald, Yike Ni, Deqiang Niu, Russell C. Petter, Juswinder Singh, Chittari Pabba
  • MK2 INHIBITORS AND USES THEREOF
    Publication number: 20190135835
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Application
    Filed: November 19, 2018
    Publication date: May 9, 2019
    Inventors: Matthew David Alexander, Joseph John McDonald, Yike Ni, Deqiang Niu, Russell C. Petter, Lixin Qiao, Juswinder Singh, Tao Wang, Zhendong Zhu
  • MK2 inhibitors and uses thereof
    Patent number: 10253040
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: April 9, 2019
    Assignee: Celgene CAR LLC
    Inventors: Matthew David Alexander, Claudio Chuaqui, John Malona, Joseph John McDonald, Yike Ni, Deqiang Niu, Russell C. Petter, Juswinder Singh, Chittari Pabba
  • MK2 inhibitors and uses thereof
    Patent number: 10138256
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: November 27, 2018
    Assignee: Celgene CAR LLC
    Inventors: Matthew David Alexander, Joseph John McDonald, Yike Ni, Deqiang Niu, Russell C. Petter, Lixin Qiao, Juswinder Singh, Tao Wang, Zhendong Zhu
  • MK2 inhibitors and uses thereof
    Patent number: 9790235
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: October 17, 2017
    Assignee: Celgene CAR LLC
    Inventors: Matthew David Alexander, Claudio Chuaqui, John Malona, Joseph John McDonald, Yike Ni, Deqiang Niu, Russell C. Petter, Juswinder Singh, Chittari Pabba
  • MK2 INHIBITORS AND USES THEREOF
    Publication number: 20170114073
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Application
    Filed: September 29, 2016
    Publication date: April 27, 2017
    Inventors: Matthew David Alexander, Claudio Chuaqui, John Malona, Joseph John McDonald, Yike Ni, Deqiang Niu, Russell C. Petter, Juswinder Singh, Chittari Pabba
  • MK2 inhibitors and uses thereof
    Patent number: 9458175
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: October 4, 2016
    Assignee: Celgene Avilomics Research, Inc.
    Inventors: Matthew David Alexander, Claudio Chuaqui, John Malona, Joseph John McDonald, Yike Ni, Deqiang Niu, Russell C. Petter, Juswinder Singh, Chittari Pabba
  • MK2 INHIBITORS AND USES THEREOF
    Publication number: 20160075720
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Application
    Filed: September 16, 2015
    Publication date: March 17, 2016
    Inventors: Matthew David Alexander, Claudio Chuaqui, John Malona, Joseph John McDonald, Yike Ni, Deqiang Niu, Russell C. Petter, Juswinder Singh
  • MK2 INHIBITORS AND USES THEREOF
    Publication number: 20150376208
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same.
    Type: Application
    Filed: January 14, 2014
    Publication date: December 31, 2015
    Applicant: Celgene Avilomics Research, Inc.
    Inventors: Matthew David ALEXANDER, Joseph John MCDONALD, Yike NI, Deqiang NIU, Russell C. PETTER, Lixin QIAO, Juswinder SINGH, Tao WANG, Zhendong ZHU
  • Substituted imidazo[1,5-a]quinoxalines useful as inhibitors of phosphodiesterase 10 for the treatment of neurological and other disorders
    Patent number: 7875618
    Abstract: The invention relates to imidazo[1,5-a]quinoxaline derivatives having Formula IIa: to processes for preparing them, to pharmaceutical preparations which comprise these compounds and to the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 10 (PDE10), as active compounds for treating central nervous system diseases of mammals, including humans.
    Type: Grant
    Filed: November 25, 2008
    Date of Patent: January 25, 2011
    Assignees: Wyeth, elbion GmbH
    Inventors: Michael S. Malamas, Yike Ni, James Joseph Erdei, Norbert Höfgen, Hans Stange, Rudolf Schindler, Ute Egerland, Barbara Langen
  • IMIDAZO[5,1-C][1,2,4]BENZOTRIAZINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASES
    Publication number: 20100120763
    Abstract: The invention relates to imidazo[5,1-c][1,2,4]benzotriazine derivatives of formula I: which are inhibitors of phosphodiesterase 2 or 10 useful in treating central nervous system diseases such as psychosis and also in treating, for example, obesity, type 2 diabetes, metabolic syndrome, glucose intolerance, and pain.
    Type: Application
    Filed: November 6, 2009
    Publication date: May 13, 2010
    Applicant: WYETH
    Inventors: Hans Stange, Barbara Langen, Ute Egerland, Norbert Hoefgen, Martina Priebs, Michael S. Malamas, James Joseph Erdei, Yike Ni
  • Triazine derivatives as inhibitors of phosphodiesterases
    Publication number: 20100120762
    Abstract: The invention relates to triazine derivatives of formula (I): which are inhibitors of phosphodiesterase 2 or 10, useful in treating central nervous system diseases such as psychosis and also in treating, for example, obesity, type 2 diabetes, metabolic syndrome, glucose intolerance, and pain.
    Type: Application
    Filed: November 6, 2009
    Publication date: May 13, 2010
    Applicant: WYETH
    Inventors: Hans Stange, Barbara Langen, Ute Egerland, Norbert Hoefgen, Martina Priebs, Michael S. Malamas, James Joseph Erdei, Yike Ni
  • Pyrido[3,2-E]Pyrazines, Process For Preparing The Same, And Their Use As Inhibitors Of Phosphodiesterase 10
    Publication number: 20090143361
    Abstract: The invention relates to pyrido[3,2-e]pyrazines, to processes for preparing them, to pharmaceutical compositions which comprise these compounds and to the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 10, as active compounds for treating central nervous system disorders, obesity, and metabolic disorders.
    Type: Application
    Filed: November 25, 2008
    Publication date: June 4, 2009
    Applicants: ELBION GMBH, WYETH
    Inventors: Michael S. Malamas, Yike Ni, James Joseph Erdei, Hans Stange, Rudolf Schindler, Norbert Hofgen, Ute Egerland, Barbara Langen
  • ARYL AND HETEROARYL FUSED IMIDAZO[1,5-a]PYRAZINES AS INHIBITORS OF PHOSPHODIESTERASE 10
    Publication number: 20090143367
    Abstract: The invention relates to imidazo[1,5-a]pyrazine derivatives, to processes for preparing them, to pharmaceutical preparations which comprise these compounds and to the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 10 (PDE10), as active compounds for treating central nervous system diseases of mammals, including humans.
    Type: Application
    Filed: November 25, 2008
    Publication date: June 4, 2009
    Applicants: ELBION GMBH, WYETH
    Inventors: Michael S. Malamas, Yike Ni, James Joseph Erdei, Norbert Hofgen, Hans Stange, Rudolf Schindler, Ute Egerland, Barbara Langen