Patents by Inventor Yike Yang

Yike Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition of 5-fluorouracil and refining method therefor
    Patent number: 11866413
    Abstract: Disclosed is a method for refining 5-fluorouracil, comprising the following steps: dissolving 5-fluorouracil in an organic solvent, preferably DMSO, heating and stirring until dissolved; naturally cooling the filtrate until a crystal is precipitated; filtering, washing a filter cake using a polar solvent, and draining and drying under reduced pressure. By using the new refining method, the content of impurities in 5-fluorouracil may be reduced to less than 0.01%, the product purity is more than 99.98%, and the refining yield is higher than 70%. In addition, the refining method of the present invention has a simple process, convenient operation, low production costs, high product purity, a stable process, and is suitable for industrial production.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: January 9, 2024
    Assignee: SHANGHAI XUDONG HAIPU PHARMACEUTICAL CO., LTD
    Inventors: Xiaolin Chen, Pengfei Gao, Yike Yang, Yi Liang, Yafeng Zhan
  • Composition of 5-Fluorouracil and Refining Method Therefor
    Publication number: 20220348548
    Abstract: Disclosed is a method for refining 5-fluorouracil, comprising the following steps: dissolving 5-fluorouracil in an organic solvent, preferably DMSO, heating and stirring until dissolved; naturally cooling the filtrate until a crystal is precipitated; filtering, washing a filter cake using a polar solvent, and draining and drying under reduced pressure. By using the new refining method, the content of impurities in 5-fluorouracil may be reduced to less than 0.01%, the product purity is more than 99.98%, and the refining yield is higher than 70%. In addition, the refining method of the present invention has a simple process, convenient operation, low production costs, high product purity, a stable process, and is suitable for industrial production.
    Type: Application
    Filed: January 10, 2020
    Publication date: November 3, 2022
    Inventors: Xiaolin Chen, Pengfei Gao, Yike Yang, Yi Liang, Yafeng Zhan