Patents by Inventor Yiliang Ding

Yiliang Ding has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Low sequence bias single-stranded DNA ligation
    Patent number: 10640828
    Abstract: The invention provides compositions and methods for ligating single stranded nucleic acids wherein the ligation is based on fast, efficient, and low-sequence bias hybridization of an acceptor molecule with a donor molecule. In one embodiment, the structure of the donor molecule comprises a stem-loop intramolecular nucleotide base pairing (i.e., hairpin) and a 3?-overhang region such that the overhang is able to hybridize to nucleotides present in the 3? end of the acceptor molecule.
    Type: Grant
    Filed: October 17, 2017
    Date of Patent: May 5, 2020
    Assignee: The Penn State Research Foundation
    Inventors: Philip C. Bevilacqua, Sarah M. Assmann, Yiliang Ding, Chun Kit Kwok
  • Low Sequence Bias Single-Stranded DNA Ligation
    Publication number: 20180030494
    Abstract: The invention provides compositions and methods for ligating single stranded nucleic acids wherein the ligation is based on fast, efficient, and low-sequence bias hybridization of an acceptor molecule with a donor molecule. In one embodiment, the structure of the donor molecule comprises a stem-loop intramolecular nucleotide base pairing (i.e., hairpin) and a 3?-overhang region such that the overhang is able to hybridize to nucleotides present in the 3? end of the acceptor molecule.
    Type: Application
    Filed: October 17, 2017
    Publication date: February 1, 2018
    Inventors: Philip C. Bevilacqua, Sarah M. Assmann, Yiliang Ding, Chun Kit Kwok
  • Low sequence bias single-stranded DNA ligation
    Patent number: 9816120
    Abstract: The invention provides compositions and methods for ligating single stranded nucleic acids wherein the ligation is based on fast, efficient, and low-sequence bias hybridization of an acceptor molecule with a donor molecule. In one embodiment, the structure of the donor molecule comprises a stem-loop intramolecular nucleotide base pairing (i.e., hairpin) and a 3?-overhang region such that the overhang is able to hybridize to nucleotides present in the 3? end of the acceptor molecule.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: November 14, 2017
    Assignee: THE PENN STATE RESEARCH FOUNDATION
    Inventors: Philip C. Bevilacqua, Sarah M. Assmann, Yiliang Ding, Chun Kit Kwok
  • Low Sequence Bias Single-Stranded DNA Ligation
    Publication number: 20140193860
    Abstract: The invention provides compositions and methods for ligating single stranded nucleic acids wherein the ligation is based on fast, efficient, and low-sequence bias hybridization of an acceptor molecule with a donor molecule. In one embodiment, the structure of the donor molecule comprises a stem-loop intramolecular nucleotide base pairing (i.e., hairpin) and a 3?-overhang region such that the overhang is able to hybridize to nucleotides present in the 3? end of the acceptor molecule.
    Type: Application
    Filed: January 9, 2014
    Publication date: July 10, 2014
    Applicant: The Penn State Research Foundation
    Inventors: Philip C. Bevilacqua, Sarah M. Assmann, Yiliang Ding, Chun Kit Kwok