Patents by Inventor Yiling Luo

Yiling Luo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR MULTIVALENT SURFACE DISPLAY ON ENVELOPED PARTICLES
    Publication number: 20240360181
    Abstract: Disclosed herein are recombinant fusion proteins comprising transmembrane domains, a display polypeptides, and oligomerization domains wherein when the recombinant fusion protein is expressed on the surface of an enveloped particle, the recombinant fusion protein is displayed in an oligomeric format, and enveloped particles containing the same, and methods of usc.
    Type: Application
    Filed: May 19, 2022
    Publication date: October 31, 2024
    Inventors: Chang-Zheng CHEN, Michael CHEN, Yiling LUO
  • IMMUNE CHECKPOINT MULTIVALENT PARTICLES COMPOSITIONS AND METHODS OF USE
    Publication number: 20240252613
    Abstract: Provided herein are multivalent particles and compositions of multivalent particles expressing immune checkpoint molecules.
    Type: Application
    Filed: May 19, 2022
    Publication date: August 1, 2024
    Inventors: Chang-Zheng CHEN, Yiling LUO, Michael CHEN, Hua ZHOU, Tian-Qiang SUN, Michael LINCOLN
  • ANTIBODY-BASED ANTIVIRUS COMPOSITIONS AND METHODS OF USE
    Publication number: 20240254203
    Abstract: Provided herein are antibody-based antiviruses comprising a fusion protein that comprises a transmembrane polypeptide and an antibody which binds to a surface protein of a virus, wherein the fusion protein is expressed at a valency of at least about 10 copies on a surface of the antivirus, and wherein the antibody neutralizes the virus when expressed within the fusion protein on the surface of the antivirus but does not neutralize the virus when expressed as an isolated antibody. Further provided herein are antibody-based antiviruses for treating a viral infection (e.g., SARS-COV-2).
    Type: Application
    Filed: May 19, 2022
    Publication date: August 1, 2024
    Inventors: Michael CHEN, Chang-Zheng CHEN, Yiling LUO, Hua ZHOU
  • MULTIVALENT PARTICLES COMPOSITIONS AND METHODS OF USE
    Publication number: 20220332769
    Abstract: Provided herein are multivalent particles and compositions of multivalent particles for blocking viral infection.
    Type: Application
    Filed: June 30, 2022
    Publication date: October 20, 2022
    Inventors: Chang-Zheng Chen, Guoqiang Dong, Yiling Luo, Hua Zhou, Tian-Qiang Sun, Michael Chen
  • Multivalent particles compositions and methods of use
    Patent number: 11453705
    Abstract: Provided herein are multivalent particles and compositions of multivalent particles for blocking viral infection.
    Type: Grant
    Filed: October 29, 2021
    Date of Patent: September 27, 2022
    Assignee: ACHELOIS BIOPHARMA, INC.
    Inventors: Chang-Zheng Chen, Guoqiang Dong, Yiling Luo, Hua Zhou, Tian-Qiang Sun, Michael Chen
  • METHODS OF MODULATING CD160 FUNCTION IN THE ANTIGEN-SPECIFIC IMMUNE CELL AND USES THEREOF
    Publication number: 20220152098
    Abstract: The present invention provides modified antigen-specific immune cells expressing an exogenous CD 160 protein. In some embodiments, the modified antigen-specific immune cell further comprises a functional exogenous receptor, such as an engineered TCR or a CAR. The present invention also provides methods of modulating CD 160 activity in antigen-specific immune cells. The present invention also provides methods and pharmaceutical compositions for cancer treatment using the modified antigen-specific immune cells and the modulators of CD 160 activity described herein.
    Type: Application
    Filed: February 28, 2020
    Publication date: May 19, 2022
    Inventors: Chang-Zheng CHEN, Hua ZHOU, Tian-Qiang SUN, Yiling LUO, Guoqiang DONG
  • MULTIVALENT PARTICLES COMPOSITIONS AND METHODS OF USE
    Publication number: 20220135626
    Abstract: Provided herein are multivalent particles and compositions of multivalent particles for blocking viral infection.
    Type: Application
    Filed: October 29, 2021
    Publication date: May 5, 2022
    Inventors: Chang-Zheng Chen, Guoqiang Dong, Yiling Luo, Hua Zhou, Tian-Qiang Sun, Michael Chen