Patents by Inventor Yiming Shao

Yiming Shao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190185405
    Abstract: The disclosure provides a method for synthesizing paraphthaloyl chloride through terephthalic acid chlorination in a reaction mode of a microchannel continuous flow. Compared with an existing technology, this method has characteristics of accurate control of reaction conditions, high phosgene/triphosgene utilization ratio, low catalyst dosage, high TPA conversion ratio within few tens of seconds of reaction time, high TPC yield and the like.
    Type: Application
    Filed: July 7, 2017
    Publication date: June 20, 2019
    Inventors: Lin XU, Yiming WANG, Bo SHAO, Kehong DING, Hui YAN, Chenchao BIAN, Hui ZHAO, Yushuang WANG
  • Patent number: 10251948
    Abstract: Provided are antigenic polypeptides of HIV envelope glycoproteins which are constructed based on amino acid mutation of attenuated live vaccine of Equine Infectious Anemia Virus, DNA constructions and recombinant virus vectors comprising polynucleotides encoding said polypeptides, antibodies against said polypeptides as well as uses thereof in preventing and treating HIV infection. Said antigenic polypeptides and vaccines can induce high titer neutralization antibodies against HIV in organism.
    Type: Grant
    Filed: January 21, 2015
    Date of Patent: April 9, 2019
    Assignee: National Center for AIDS/STD Control And Prevention, Chinese Center for Disease Control and Prevention
    Inventors: Yiming Shao, Lianxing Liu, Rongxian Shen
  • Publication number: 20190002539
    Abstract: Broadly neutralizing antibodies against HIV-1 which specifically bind to gp120 of HIV-1, a method of preparing such antibodies and the use thereof are provided.
    Type: Application
    Filed: January 26, 2017
    Publication date: January 3, 2019
    Inventors: Yiming Shao, Jiang Zhu, Yuxing Li, Ian A. Wilson, Leopold Kong, Bin Ju, Linling He, Li Ren, Yajing Chen, Jiandong Liu
  • Publication number: 20180119171
    Abstract: Provided is a recombinant replicative vaccinia virus, the virus comprising a polynucleotide encoding HSV-TK and HIV antigens. Also provided is a live vector HIV vaccine composition comprising the recombinant replicative vaccinia virus.
    Type: Application
    Filed: January 12, 2018
    Publication date: May 3, 2018
    Inventors: Yiming Shao, Qicheng ZHANG, Ying Liu
  • Publication number: 20150132332
    Abstract: Provided are antigenic polypeptides of HIV envelope glycoproteins which are constructed based on amino acid mutation of attenuated live vaccine of Equine Infectious Anemia Virus, DNA constructions and recombinant virus vectors comprising polynucleotides encoding said polypeptides, antibodies against said polypeptides as well as uses thereof in preventing and treating HIV infection. Said antigenic polypeptides and vaccines can induce high titer neutralization antibodies against HIV in organism.
    Type: Application
    Filed: January 21, 2015
    Publication date: May 14, 2015
    Inventors: YIMING SHAO, LIANXING LIU, RONGXIAN SHEN
  • Patent number: 8956620
    Abstract: Provided are antigenic polypeptides of HIV envelope glycoproteins which are constructed based on amino acid mutation of attenuated live vaccine of Equine Infectious Anemia Virus, DNA constructions and recombinant virus vectors comprising polynucleotides encoding said polypeptides, antibodies against said polypeptides as well as uses thereof in preventing and treating HIV infection. Said antigenic polypeptides and vaccines can induce high titer neutralization antibodies against HIV in organism.
    Type: Grant
    Filed: May 27, 2009
    Date of Patent: February 17, 2015
    Assignee: National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention
    Inventors: Yiming Shao, Lianxing Liu, Rongxian Shen
  • Publication number: 20110195084
    Abstract: Provided are antigenic polypeptides of HIV envelope glycoproteins which are constructed based on amino acid mutation of attenuated live vaccine of Equine Infectious Anemia Virus, DNA constructions and recombinant virus vectors comprising polynucleotides encoding said polypeptides, antibodies against said polypeptides as well as uses thereof in preventing and treating HIV infection. Said antigenic polypeptides and vaccines can induce high titer neutralization antibodies against HIV in organism.
    Type: Application
    Filed: May 27, 2009
    Publication date: August 11, 2011
    Applicant: National Center for AIDS/STD Control and Preventio Chinese Center for Disease Control and Prevention
    Inventors: Yiming Shao, Lianxing Liu, Rongxian Shen
  • Publication number: 20100034851
    Abstract: Replicative live-vector vaccine against AIDS expressing antigen of human immunodeficiency virus (HIV) and its application are provided. Said vaccine is constructed on the basis of replicative vaccinia virus, such as vaccinia virus TianTan strain. The replicative live-vector vaccine of present invention is capable of inducing high level humoral and cell immunoresponse against HIV. The vector for constructing said vaccine, and immunization procedure using said vaccine are also provided.
    Type: Application
    Filed: February 16, 2007
    Publication date: February 11, 2010
    Inventors: Yiming Shao, Ying Liu, Jianyuan Liu
  • Patent number: 6987020
    Abstract: This invention discloses the full-length proviral genome DNA sequence of Donkey Leukocyte Attenuated Equine Infectious Anemia Virus Vaccine strain, nucleotide and amino acid sequences of all functional genes, and uses of each functional gene and its expression product. The vaccine strain involved in this invention was derived from an isolate in China.
    Type: Grant
    Filed: April 21, 2000
    Date of Patent: January 17, 2006
    Assignees: National Center for Aids Prevention and Control, Harbin Veterinary Research Institute, Chinese Academy of Agriculture Science
    Inventors: Yiming Shao, Rongxian Shen, Gang Chen, Kangzhen Yu, Pinliang Pan, Bin Jia, Yi Feng, Fel Xue, Wenhua Xiang, Xiujuan Fan, Xieoling Lu, Liping Zhao