Patents by Inventor Yin-Chun Tien
Yin-Chun Tien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220298481Abstract: A method for preparing zonal layered chondrocyte sheets, comprising the steps: (a) providing a cartilage sample from a subject; (b) isolating chondrocytes from the cartilage sample and then isolating superficial zone chondrocytes, middle zone chondrocytes and deep zone chondrocytes from the chondrocytes; (c) culturing the deep zone chondrocytes until reaching 100% cell confluence to form a deep zone chondrocyte sheet; (d) seeding the middle zone chondrocytes on the top of the cultured deep zone chondrocyte sheet from the step (c) and culturing the middle zone chondrocytes until reaching 100% cell confluence to form a middle zone chondrocyte sheet; and (e) seeding the superficial zone chondrocytes on the top of the cultured middle zone chondrocyte sheet from the step (d) and culturing the superficial zone chondrocytes until reaching 100% cell confluence to form a superficial zone chondrocyte sheet to obtain the zonal layered chondrocyte sheets.Type: ApplicationFiled: March 18, 2022Publication date: September 22, 2022Applicant: KAOHSIUNG MEDICAL UNIVERSITYInventor: YIN-CHUN TIEN
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Patent number: 7163651Abstract: The present invention discloses a method for making a porous calcium phosphate article including i) preparing a shaped article from a paste containing a calcium phosphate cement, a pore-forming powder and a setting liquid; ii) immersing the shaped article in an immersing liquid for a period of time so that the pore-forming powder is dissolved in the immersing liquid, creating pores in said shaped article; and iii) removing the resulting porous shaped article from the immersing liquid, wherein the resulting porous shaped article has an improved compressive strength. The porous shaped calcium phosphate article of the present invention may be used as a tissue-engineered scaffold, medical implant or a reinforcing constituent of a composite.Type: GrantFiled: February 19, 2004Date of Patent: January 16, 2007Assignee: Calcitec, Inc.Inventors: Jiin-Huey Chern Lin, Chien-Ping Ju, Yin-Chun Tien, Chih-Hung Tsai, Chao-Chin Ning, Chung-Po Chao
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Patent number: 7119038Abstract: The present invention discloses a method for making a porous calcium phosphate article including i) preparing a shaped article from a paste containing a calcium phosphate cement, a pore-forming powder and a setting liquid; ii) immersing the shaped article in an immersing liquid for a period of time so that the pore-forming powder is dissolved in the immersing liquid, creating pores in said shaped article; and iii) removing the resulting porous shaped article from the immersing liquid, wherein the resulting porous shaped article has an improved compressive strength. The porous shaped calcium phosphate article of the present invention may be used as a tissue-engineered scaffold, medical implant or a reinforcing constituent of a composite.Type: GrantFiled: March 3, 2005Date of Patent: October 10, 2006Assignee: Calcitec, Inc.Inventors: Jiin-Huey Chern Lin, Chien-Ping Ju, Yin-Chun Tien, Chih-Hung Tsai, Chao-Chin Ning, Chung-Po Chao
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Patent number: 7097793Abstract: The present invention discloses a method for making a porous calcium phosphate article including i) preparing a shaped article from a paste containing a calcium phosphate cement, a pore-forming powder and a setting liquid; ii) immersing the shaped article in an immersing liquid for a period of time so that the pore-forming powder is dissolved in the immersing liquid, creating pores in said shaped article; and iii) removing the resulting porous shaped article from the immersing liquid, wherein the resulting porous shaped article has an improved compressive strength. The porous shaped calcium phosphate article of the present invention may be used as a tissue-engineered scaffold, medical implant or a reinforcing constituent of a composite.Type: GrantFiled: March 3, 2005Date of Patent: August 29, 2006Assignee: Calcitec, Inc.Inventors: Jiin-Huey Chern Lin, Chien-Ping Ju, Yin-Chun Tien, Chih-Hung Tsai, Chao-Chin Ning, Chung-Po Chao
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Patent number: 7083750Abstract: The present invention discloses a method for making a porous calcium phosphate article including i) preparing a shaped article from a paste containing a calcium phosphate cement, a pore-forming powder and a setting liquid; ii) immersing the shaped article in an immersing liquid for a period of time so that the pore-forming powder is dissolved in the immersing liquid, creating pores in said shaped article; and iii) removing the resulting porous shaped article from the immersing liquid, wherein the resulting porous shaped article has an improved compressive strength. The porous shaped calcium phosphate article of the present invention may be used as a tissue-engineered scaffold, medical implant or a reinforcing constituent of a composite.Type: GrantFiled: March 3, 2005Date of Patent: August 1, 2006Assignee: Calcitec, Inc.Inventors: Jiin-Huey Chern Lin, Chien-Ping Ju, Yin-Chun Tien, Chih-Hung Tsai, Chao-Chin Ning, Chung-Po Chao
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Publication number: 20050186449Abstract: The present invention discloses a method for making a porous calcium phosphate article including i) preparing a shaped article from a paste containing a calcium phosphate cement, a pore-forming powder and a setting liquid; ii) immersing the shaped article in an immersing liquid for a period of time so that the pore-forming powder is dissolved in the immersing liquid, creating pores in said shaped article; and iii) removing the resulting porous shaped article from the immersing liquid, wherein the resulting porous shaped article has an improved compressive strength. The porous shaped calcium phosphate article of the present invention may be used as a tissue-engineered scaffold, medical implant or a reinforcing constituent of a composite.Type: ApplicationFiled: March 3, 2005Publication date: August 25, 2005Inventors: Jiin-Huey Lin, Chien-Ping Ju, Yin-Chun Tien, Chih-Hung Tsai, Chao-Chin Ning, Chung-Po Chao
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Publication number: 20050184417Abstract: The present invention discloses a method for making a porous calcium phosphate article including i) preparing a shaped article from a paste containing a calcium phosphate cement, a pore-forming powder and a setting liquid; ii) immersing the shaped article in an immersing liquid for a period of time so that the pore-forming powder is dissolved in the immersing liquid, creating pores in said shaped article; and iii) removing the resulting porous shaped article from the immersing liquid, wherein the resulting porous shaped article has an improved compressive strength. The porous shaped calcium phosphate article of the present invention may be used as a tissue-engineered scaffold, medical implant or a reinforcing constituent of a composite.Type: ApplicationFiled: February 19, 2004Publication date: August 25, 2005Applicant: CANA LAB CORPORATIONInventors: Jiin-Huey Chern Lin, Chien-Ping Ju, Yin-Chun Tien, Chih-Hung Tsai, Chao-Chin Ning, Chung-Po Chao
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Publication number: 20050186354Abstract: The present invention discloses a method for making a porous calcium phosphate article including i) preparing a shaped article from a paste containing a calcium phosphate cement, a pore-forming powder and a setting liquid; ii) immersing the shaped article in an immersing liquid for a period of time so that the pore-forming powder is dissolved in the immersing liquid, creating pores in said shaped article; and iii) removing the resulting porous shaped article from the immersing liquid, wherein the resulting porous shaped article has an improved compressive strength. The porous shaped calcium phosphate article of the present invention may be used as a tissue-engineered scaffold, medical implant or a reinforcing constituent of a composite.Type: ApplicationFiled: March 3, 2005Publication date: August 25, 2005Inventors: Jiin-Huey Lin, Chien-Ping Ju, Yin-Chun Tien, Chih-Hung Tsai, Chao-Chin Ning, Chung-Po Chao
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Publication number: 20050186353Abstract: The present invention discloses a method for making a porous calcium phosphate article including i) preparing a shaped article from a paste containing a calcium phosphate cement, a pore-forming powder and a setting liquid; ii) immersing the shaped article in an immersing liquid for a period of time so that the pore-forming powder is dissolved in the immersing liquid, creating pores in said shaped article; and iii) removing the resulting porous shaped article from the immersing liquid, wherein the resulting porous shaped article has an improved compressive strength. The porous shaped calcium phosphate article of the present invention may be used as a tissue-engineered scaffold, medical implant or a reinforcing constituent of a composite.Type: ApplicationFiled: March 3, 2005Publication date: August 25, 2005Inventors: Jiin-Huey Lin, Chien-Ping Ju, Yin-Chun Tien, Chih-Hung Tsai, Chao-Chin Ning, Chung-Po Chao
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Publication number: 20050184418Abstract: The present invention discloses a method for making a porous calcium phosphate article including i) preparing a shaped article from a paste containing a calcium phosphate cement, a pore-forming powder and a setting liquid; ii) immersing the shaped article in an immersing liquid for a period of time so that the pore-forming powder is dissolved in the immersing liquid, creating pores in said shaped article; and iii) removing the resulting porous shaped article from the immersing liquid, wherein the resulting porous shaped article has an improved compressive strength. The porous shaped calcium phosphate article of the present invention may be used as a tissue-engineered scaffold, medical implant or a reinforcing constituent of a composite.Type: ApplicationFiled: March 3, 2005Publication date: August 25, 2005Inventors: Jiin-Huey Lin, Chien-Ping Ju, Yin-Chun Tien, Chih-Hung Tsai, Chao-Chin Ning, Chung-Po Chao
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Publication number: 20030216777Abstract: Augmentation of the tendon-bond interfacial healing, for example the tendon-bond interfacial healing in the cruciate ligament reconstruction, by filling the interfacial gap with a paste of calcium phosphate cement, a paste of bioactive glass, or a paste of calcium sulfate is disclosed.Type: ApplicationFiled: May 16, 2002Publication date: November 20, 2003Inventors: Yin-Chun Tien, Jiin-Huey Chern Lin, Chien-Ping Ju