Abstract: The present disclosure relates to methods, compositions, and kits for isolating target nucleic acids below a target size from a sample comprising nucleic acid components. In some embodiments, the methods involve one or more aqueous two-phase system (ATPS) compositions, at least one solid phase medium, and at least one buffer. Some embodiments provide a kit comprising one or more ATPS compositions, at least one solid phase medium, and at least one buffer. Other embodiments provide methods for diagnosing a disease or condition using the methods described herein.

Abstract: The present disclosure relates to methods, compositions, and kits for concentrating and purifying at least one target analyte from a clinical biological sample. In some embodiments, the methods involve one or more aqueous two-phase system (ATPS) compositions and at least one solid phase medium. Some embodiments provide a kit comprising one or more ATPS compositions, a binding buffer; and a solid phase medium. Other embodiments provide methods of treating cancers or infectious diseases in a patient in need thereof.

Abstract: An upper of an article of footwear comprises a plurality of stretch zones each having a respective stretching capability. Suitable example stretch zones may include four-way stretch zones, two-way stretch zones, and/or lock-out zones. In some examples, an upper having a plurality of stretch zones comprises a single continuous piece of material configured to have regions of different stretching capability. The single piece of material may comprise a layered material having two stretchable outer layers, wherein a plurality of stretch zones of the piece of material are defined by corresponding intermediate layers disposed at selected locations between the outer layers. Examples of intermediate layers providing two-way stretch, four-way stretch, and little or no stretch are disclosed.

Abstract: One or more computer processors receive a pattern string comprising a pointer to a pattern search point and a string comprising a pointer to a search point; determine a plausible search point within the string for the pattern character; execute a search string (SRST) instruction with the determined search point and the pattern character; compute a pattern offset comprising a difference between a first occurrence of the determined pattern character located within the pattern string but not in the correct position and a current pattern character position; execute a subsequent SRST instruction with the current pattern character position and the computed offset set as a new search point; and responsive to identifying all pattern characters in the correct position within the string based on the executed subsequent SRST instruction, transmit memory address associated with a substring comprised of the string and corresponding pattern characters in the correct position.

Abstract: An upper of an article of footwear comprises a plurality of stretch zones each having a respective stretching capability. Suitable example stretch zones may include four-way stretch zones, two-way stretch zones, and/or lock-out zones. In some examples, an upper having a plurality of stretch zones comprises a single continuous piece of material configured to have regions of different stretching capability. The single piece of material may comprise a layered material having two stretchable outer layers, wherein a plurality of stretch zones of the piece of material are defined by corresponding intermediate layers disposed at selected locations between the outer layers. Examples of intermediate layers providing two-way stretch, four-way stretch, and little or no stretch are disclosed.

Abstract: A spectacle lens can inhibit ametropia of the eyes and ensure full visibility. The spectacle lens comprises: first refraction areas and second refraction areas. Each first refraction area has a first refraction force that may be based on a prescription for correcting the ametropia of the eyes. Each second refraction area has a refraction force different from the first refraction force and may function to focus images on the positions except the retina of the eyes, to inhibit the development of the ametropia. Near the central part of the lens, the second refraction areas form a plurality of independent island-shaped areas, and the first refraction areas form the areas beyond the areas of the second refraction areas.

Abstract: A technology for inhibition of myopia progression adapted to the RPR of the wearer is provided. A spectacle lens and related technology are provided that include a base area that causes a beam that enters through an object-side surface to exit through an eye-side surface and converge on a retina via the eye, and a plurality of defocus areas that each contact the base area and have a characteristic whereby a beam that passes through at least a portion of the defocus area is incident on the retina as a diverging ray, and, in not less than half of the plurality of defocus areas, at least one of a defocus power and a size of each defocus area is set, so as to compensate for a change in retinal spot size due to relative peripheral refraction (RPR) that depends on an eccentricity angle of the eye of the wearer.

Abstract: A spectacle lens can inhibit ametropia of the eyes and ensure full visibility. The spectacle lens comprises: first refraction areas and second refraction areas. Each first refraction area has a first refraction force that may be based on a prescription for correcting the ametropia of the eyes. Each second refraction area has a refraction force different from the first refraction force and may function to focus images on the positions except the retina of the eyes, to inhibit the development of the ametropia. Near the central part of the lens, the second refraction areas form a plurality of independent island-shaped areas, and the first refraction areas form the areas beyond the areas of the second refraction areas.

Abstract: An article of footwear may include an outsole having an opening extending from a top face of the outsole to a ground-contacting face of the outsole, and a traction member disposed within the opening in the outsole. The traction member has a protruding portion and flange portion extending from an upper end of the protruding portion. The flange portion is secured to the top face of the outsole.

Abstract: A dual-layered midsole for footwear includes an internal midsole layer and an external midsole layer, which are coupled to and separated by a Strobel board. The internal midsole layer may compress and expand with the movement of a wearer of an article of footwear including the dual-layered midsole, while the external midsole may provide stability and cushion for the wearer. Materials selected for the internal and external midsole layers may provide tuned viscoelastic properties to different areas of the midsole as a function of midsole layer thickness at each sole area.

Abstract: Methods and systems for determining a ball shot attempt location on a ball court are disclosed. The method includes receiving an input video, where the input video includes the ball shot attempt and one or more players; receiving a declared ball shot attempt; determining a potential shooter by detecting a moving object flow in the input video; determining a potential shooter image region in the image plane by analyzing an overlapping image area of the ball trajectory and the potential shooter; determining a shooter foot-on-court time; determining a most probable pair of shooter legs in the potential shooter image region; determining a shooter foot location based on the most probable pair of shooter legs; and determining a ball shot attempt location on the ball court by applying a camera projection to the shooter foot location.

Abstract: An article of footwear may include an outsole having an opening extending from a top face of the outsole to a ground-contacting face of the outsole, and a traction member disposed within the opening in the outsole. The traction member has a protruding portion and flange portion extending from an upper end of the protruding portion. The flange portion is secured to the top face of the outsole.

Abstract: An article of footwear may include an outsole having an opening extending from a top face of the outsole to a ground-contacting face of the outsole, and a traction member disposed within the opening in the outsole. The traction member has a protruding portion and flange portion extending from an upper end of the protruding portion. The flange portion is secured to the top face of the outsole.

Abstract: A dual-layered midsole for footwear includes an internal midsole layer and an external midsole layer, which are coupled to and separated by a Strobel board. The internal midsole layer may compress and expand with the movement of a wearer of an article of footwear including the dual-layered midsole, while the external midsole may provide stability and cushion for the wearer. Materials selected for the internal and external midsole layers may provide tuned viscoelastic properties to different areas of the midsole as a function of midsole layer thickness at each sole area.

Abstract: One or more computer processors receive a pattern string comprising a pointer to a pattern search point and a string comprising a pointer to a search point; determine a plausible search point within the string for the pattern character; execute a search string (SRST) instruction with the determined search point and the pattern character; compute a pattern offset comprising a difference between a first occurrence of the determined pattern character located within the pattern string but not in the correct position and a current pattern character position; execute a subsequent SRST instruction with the current pattern character position and the computed offset set as a new search point; and responsive to identifying all pattern characters in the correct position within the string based on the executed subsequent SRST instruction, transmit memory address associated with a substring comprised of the string and corresponding pattern characters in the correct position.

Abstract: Provided herein is concentric annular multi-zone lens for retarding myopia progression in a human eye. The lens comprises: a plurality of correcting zones for forming a focused image on a retina of the human eye so as to correct refractive error of the human eye, wherein the correcting zone having a similar refractive power; a plurality of defocusing zones for forming images anterior to the retina so as to generate myopic defocus; and a defocusing power increasing region, in which refractive powers of defocusing zones being increasingly relatively positive towards the periphery of the lens so as to generate larger amplitude of the myopic defocus at the periphery of the retina; wherein the plurality of correcting zones and the plurality of defocusing zones are alternated in the concentric annular multi-zone lens.

Abstract: A spectacle lens can inhibit ametropia of the eyes and ensure full visibility. The spectacle lens comprises: first refraction areas and second refraction areas. Each first refraction area has a first refraction force that may be based on a prescription for correcting the ametropia of the eyes. Each second refraction area has a refraction force different from the first refraction force and may function to focus images on the positions except the retina of the eyes, to inhibit the development of the ametropia. Near the central part of the lens, the second refraction areas form a plurality of independent island-shaped areas, and the first refraction areas form the areas beyond the areas of the second refraction areas.

Abstract: A segmented sole for an article of footwear comprises a forefoot region, a heel region, and a segmentation zone disposed between the forefoot and heel region. The segmentation zone includes a plurality of segments separated from each other and from the forefoot and heel by a plurality of sipes, cuts, or gaps. The segmented sole produces bending along a segmentation axis disposed along an arch of a wearer of an article of footwear including the sole, allowing for arch support and natural foot movement.

Abstract: Methods and systems for determining a ball shot attempt location on a ball court are disclosed. The method includes receiving an input video, where the input video includes the ball shot attempt and one or more players; receiving a declared ball shot attempt; determining a potential shooter by detecting a moving object flow in the input video; determining a potential shooter image region in the image plane by analyzing an overlapping image area of the ball trajectory and the potential shooter; determining a shooter foot-on-court time; determining a most probable pair of shooter legs in the potential shooter image region; determining a shooter foot location based on the most probable pair of shooter legs; and determining a ball shot attempt location on the ball court by applying a camera projection to the shooter foot location.