Patents by Inventor Yin Lu

Yin Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260102376
    Abstract: A use of a dihydrotanshinone I derivative in preparation of a drug for treating cerebral cavernous malformations (CCMs) is provided. The dihydrotanshinone I derivative can treat CCM with excellent efficacy. The dihydrotanshinone I derivative has a chemical name of (R)-1,6-dimethyl-11-phenyl-1,10-dihydro-2H-furo[2?,3?:1,2]phenanthro[3,4-d]imidazole and a molecular formula of C25H20ON2. The research has shown that the dihydrotanshinone I derivative can play a prominent anti-CCM role in vivo. The dihydrotanshinone I derivative can remarkably reduce the lesion counts and volumes in CCM, and thus is suitable for the preparation of anti-CCM drugs.
    Type: Application
    Filed: July 31, 2025
    Publication date: April 16, 2026
    Applicant: Nanjing University of Chinese Medicine
    Inventors: Yang ZHAO, Weiwei ZHENG, Suyun YU, Jia LI, Yin LU
  • Patent number: 12583877
    Abstract: Layered super-hydrophilic Ti—Cu-MOFs and a preparation method and use thereof provided, which relates to the technical field of composite materials. According to the present application, copper ions and titanium ions are used as bimetallic centers to have a coordination reaction with rigid aromatic amine ligands, and layered super-hydrophilic Ti—Cu-MOFs with a lamellar structure is efficiently synthesized. Compared with the prior technology, the preparation method of the present application is simple, and the morphology and structure are controllable; the surface of the prepared layered super-hydrophilic Ti—Cu-MOFs are rich in hydroxyl groups, and have high adsorption capacity for phospholipid co-extracts in clinical biological samples, and thus can be used for the analysis of phenothiazine drugs and metabolites thereof in biological samples and realize one-step separation and purification, thus greatly improving the pretreatment efficiency of clinical biological samples and shortening the analysis time.
    Type: Grant
    Filed: February 5, 2024
    Date of Patent: March 24, 2026
    Assignee: ZHEJIANG SHUREN UNIVERSITY
    Inventors: Yin Lu, Yonggang Zhao, Chao Lei, Mingli Ye, Taziana Saviskaya, Andrei Ivanic
  • Patent number: 12378192
    Abstract: Disclosed by the present application is a crystalline form of a capsid protein assembly inhibitor containing an N hetero five-membered ring; specifically disclosed is the crystalline form of the compound of formula I; also comprised is an the application of said crystalline form in the preparation of a drug for preventing or treating diseases benefiting from the inhibition of capsid protein assembly.
    Type: Grant
    Filed: September 28, 2020
    Date of Patent: August 5, 2025
    Assignee: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Yin Lu, Meng Guo, Mingtong Hu, Yuan Li, Wangwei Ao, Yinsheng Zhang
  • Patent number: 12342221
    Abstract: Disclosed is a multi-base station queued preambles allocation method based on collaboration between multiple agent, which provides a non-competitive preambles allocation method in a scenario of multiple base stations and multiple cells, so as to solve the congestion problem caused during random access of massive MTCDs. The devices are queued to select the preambles based on deep reinforcement learning, and a training method based on federal learning is applied, thus effectively solving the congestion problem caused by competitive access. First, the newly accessed devices are grouped and the level of priority is set according to a delay tolerance time. Then, the device are reasonably allocated to idle queues by means of a multi-agent reinforcement learning algorithm. Finally, by means of a federal training method, the neural network of each agent is synchronously optimized by means of average optimization of neural network gradients, thus completing preambles allocation to each agent.
    Type: Grant
    Filed: July 22, 2022
    Date of Patent: June 24, 2025
    Assignee: Nanjing University Of Posts And Telecommunications
    Inventors: Jun Sun, Mengzhu Guo, Yin Lu
  • Publication number: 20250088909
    Abstract: Disclosed is a multi-base station queued preambles allocation method based on collaboration between multiple agent, which provides a non-competitive preambles allocation method in a scenario of multiple base stations and multiple cells, so as to solve the congestion problem caused during random access of massive MTCDs. The devices are queued to select the preambles based on deep reinforcement learning, and a training method based on federal learning is applied, thus effectively solving the congestion problem caused by competitive access. First, the newly accessed devices are grouped and the level of priority is set according to a delay tolerance time. Then, the device are reasonably allocated to idle queues by means of a multi-agent reinforcement learning algorithm. Finally, by means of a federal training method, the neural network of each agent is synchronously optimized by means of average optimization of neural network gradients, thus completing preambles allocation to each agent.
    Type: Application
    Filed: July 22, 2022
    Publication date: March 13, 2025
    Applicant: Nanjing University Of Posts And Telecommunications
    Inventors: Jun SUN, Mengzhu GUO, Yin LU
  • Patent number: 12191940
    Abstract: A user matching and power distribution methods for a MIMO-NOMA downlink communication system is provided. The user matching method includes: dividing all users into a strong user group and a weak user group according to a channel gain sorting result; and sequentially selecting a user in the strong user group, calculating a correlation coefficient between the user and each user in the weak user group, selecting a weak user with the highest correlation coefficient as a weak user in a cluster where the strong user is located, and excluding matched users from respective user groups, until the matching between all strong users and weak users are completed. The present invention enables weak users in a cluster to experience less inter-cluster interference in scenarios where the channel correlation between users is relatively low, thereby improving the total throughput of the communication system.
    Type: Grant
    Filed: February 21, 2020
    Date of Patent: January 7, 2025
    Assignee: NANJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS
    Inventors: Yin Lu, Yihuang Qu, Chuying Yang, Taosen Li, Xiumei Wang, Hongbo Zhu
  • Publication number: 20240174700
    Abstract: Layered super-hydrophilic Ti—Cu-MOFs and a preparation method and use thereof provided, which relates to the technical field of composite materials. According to the present application, copper ions and titanium ions are used as bimetallic centers to have a coordination reaction with rigid aromatic amine ligands, and layered super-hydrophilic Ti—Cu-MOFs with a lamellar structure is efficiently synthesized. Compared with the prior technology, the preparation method of the present application is simple, and the morphology and structure are controllable; the surface of the prepared layered super-hydrophilic Ti—Cu-MOFs are rich in hydroxyl groups, and have high adsorption capacity for phospholipid co-extracts in clinical biological samples, and thus can be used for the analysis of phenothiazine drugs and metabolites thereof in biological samples and realize one-step separation and purification, thus greatly improving the pretreatment efficiency of clinical biological samples and shortening the analysis time.
    Type: Application
    Filed: February 5, 2024
    Publication date: May 30, 2024
    Inventors: Yin LU, Yonggang ZHAO, Chao LEI, Mingli YE, Taziana SAVISKAYA, Andrei IVANIC
  • Patent number: 11960521
    Abstract: The present disclosure discloses a text classification system based on feature selection and a method thereof in the technical field of natural language processing and short text classification, comprising: acquiring a text classification data set; dividing the text classification data set into a training text set and a test text set, and then pre-processing the training text set and the test text set; extracting feature entries from the pre-processed training text set through improved chi-square statistics to form feature subsets; using TF-IWF algorithm to give the weight to the extracted feature entries; based on the weighted feature entries, establishing a short text classification model based on a support vector machine; and classifying the pre-processed test text set by the short text classification model. The present disclosure solves the problem that the short text content is sparse to some extent, thereby improving the performance of short text classification.
    Type: Grant
    Filed: January 16, 2023
    Date of Patent: April 16, 2024
    Inventors: Yin Lu, Qingyuan Li, Abdusamjan Abdukirim, Jie Hu, Luocheng Wu, Yongan Guo
  • Publication number: 20230212117
    Abstract: Disclosed by the present application is a crystalline form of a capsid protein assembly inhibitor containing an N hetero five-membered ring; specifically disclosed is the crystalline form of the compound of formula I; also comprised is an the application of said crystalline form in the preparation of a drug for preventing or treating diseases benefiting from the inhibition of capsid protein assembly.
    Type: Application
    Filed: September 28, 2020
    Publication date: July 6, 2023
    Applicant: CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
    Inventors: Yin LU, Meng GUO, Mingtong HU, Yuan LI, Wangwei AO, Yinsheng ZHANG
  • Publication number: 20230214415
    Abstract: The present disclosure discloses a text classification system based on feature selection and a method thereof in the technical field of natural language processing and short text classification, comprising: acquiring a text classification data set; dividing the text classification data set into a training text set and a test text set, and then pre-processing the training text set and the test text set; extracting feature entries from the pre-processed training text set through improved chi-square statistics to form feature subsets; using TF-IWF algorithm to give the weight to the extracted feature entries; based on the weighted feature entries, establishing a short text classification model based on a support vector machine; and classifying the pre-processed test text set by the short text classification model. The present disclosure solves the problem that the short text content is sparse to some extent, thereby improving the performance of short text classification.
    Type: Application
    Filed: January 16, 2023
    Publication date: July 6, 2023
    Applicant: Nanjing University of Posts and Telecommunications
    Inventors: Yin Lu, Qingyuan Li, Abdusamjan Abdukirim, Jie Hu, Luocheng Wu, Yongan Guo
  • Patent number: 11605442
    Abstract: Embodiments of the disclosure are drawn to apparatuses methods for checking redundancy information for row addresses prior to performing various refresh operations, such as auto refresh and targeted refresh operations. In some examples, refresh operations may be multi pump refresh operations. In some examples, a targeted refresh operation may be performed prior to an auto refresh operation responsive to a multi pump refresh operation. In some examples, redundancy information for the auto refresh operation may be performed, at least in part, during the targeted refresh operation. In some examples, refresh operations on word lines may be skipped when the redundancy information indicates the word line is defective or unused.
    Type: Grant
    Filed: September 23, 2021
    Date of Patent: March 14, 2023
    Assignee: MICRON TECHNOLOGY, INC.
    Inventors: Bin Du, Liang Li, Yu Zhang, Yin Lu
  • Patent number: 11578114
    Abstract: Anti-angiogenic agents or polypeptides have an amino acid segment substantially similar to domain one of CD2. The polypeptide has a ?-sheet formed by two segments. Methods of using such agents and polypeptide are also included.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: February 14, 2023
    Inventors: Zhi-Ren Liu, Jenny Yang, Yin Lu
  • Publication number: 20230041216
    Abstract: A user matching and power distribution methods for a MIMO-NOMA downlink communication system is provided. The user matching method includes: dividing all users into a strong user group and a weak user group according to a channel gain sorting result; and sequentially selecting a user in the strong user group, calculating a correlation coefficient between the user and each user in the weak user group, selecting a weak user with the highest correlation coefficient as a weak user in a cluster where the strong user is located, and excluding matched users from respective user groups, until the matching between all strong users and weak users are completed. The present invention enables weak users in a cluster to experience less inter-cluster interference in scenarios where the channel correlation between users is relatively low, thereby improving the total throughput of the communication system.
    Type: Application
    Filed: February 21, 2020
    Publication date: February 9, 2023
    Applicant: NANJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS
    Inventors: Yin LU, Yihuang QU, Chuying YANG, Taosen LI, Xiumei WANG, Hongbo ZHU
  • Publication number: 20220363634
    Abstract: Disclosed by the present application is a crystalline form of a capsid protein assembly inhibitor containing an N hetero five-membered ring; specifically disclosed is the crystalline form of the compound of formula I; also comprised is an the application of said crystalline form in the preparation of a drug for preventing or treating diseases benefiting from the inhibition of capsid protein assembly.
    Type: Application
    Filed: September 28, 2020
    Publication date: November 17, 2022
    Applicant: CHAI, TAI TIANQING PHARMACEUTICAL GROUP CO.,LTD.
    Inventors: Yin LU, Meng GUO, Mingtong HU, Yuan LI, Wangwei AO, Yinsheng ZHANG
  • Patent number: 11420140
    Abstract: The disclosure provides an integrated separation unit for microplastics in the coastal sediments and a collection method of microplastics, belonging to the technical field of water treatment. The unit includes: a holder, a separation cylinder, a collection bottle, a central baffle plate, a baffle plate control knob, a stirring propeller, a motor, a cylinder switch, a filtration screen, a welding nozzle, a filter membrane and a vacuum pump. Using this unit for microplastic collection has the advantages of easy operation, economical and environment-friendly, high separation efficiency, and high durability.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: August 23, 2022
    Inventors: Yin Lu, Wenyong Weng, Mingli Ye, Qing Ma, Xiaolu Xu, Deyong Zhang
  • Publication number: 20220186601
    Abstract: A method for obtaining overall logging data based on an automated reasoning model is provided. The method achieves a reservoir evaluation for a reservoir matrix within a multi-depth range by generating high-quality point location prediction data. The method includes: acquiring imaging logging data and lab observing data of a stratum; inputting the imaging logging data and the lab observing data, to form dimensionless data and performing data normalization on the data; denoising known continuous data; marking a to-be-supplemented data point location; performing data supplementing for a point location in a predetermined order; and restoring a data dimension to obtain the overall logging data by supplementing. By automatically supplementing the lab observing data in analysis logging data, high-quality prediction data is obtained, which provides a basis for subsequent evaluation and analysis of the stratum, and contributes to exploration and development of resources such as oil, gas, and coal.
    Type: Application
    Filed: December 13, 2021
    Publication date: June 16, 2022
    Inventors: Wenyong WENG, Yin LU, Wujian YANG, Qing MA, Guanlin CHEN
  • Publication number: 20220068429
    Abstract: Embodiments of the disclosure are drawn to apparatuses methods for checking redundancy information for row addresses prior to performing various refresh operations, such as auto refresh and targeted refresh operations. In some examples, refresh operations may be multi pump refresh operations. In some examples, a targeted refresh operation may be performed prior to an auto refresh operation responsive to a multi pump refresh operation. In some examples, redundancy information for the auto refresh operation may be performed, at least in part, during the targeted refresh operation. In some examples, refresh operations on word lines may be skipped when the redundancy information indicates the word line is defective or unused.
    Type: Application
    Filed: September 23, 2021
    Publication date: March 3, 2022
    Applicant: MICRON TECHNOLOGY, INC.
    Inventors: Bin Du, Liang Li, Yu Zhang, Yin Lu
  • Patent number: 11152078
    Abstract: Embodiments of the disclosure are drawn to apparatuses methods for checking redundancy information for row addresses prior to performing various refresh operations, such as auto refresh and targeted refresh operations. In some examples, refresh operations may be multi pump refresh operations. In some examples, a targeted refresh operation may be performed prior to an auto refresh operation responsive to a multi pump refresh operation. In some examples, redundancy information for the auto refresh operation may be performed, at least in part, during the targeted refresh operation. In some examples, refresh operations on word lines may be skipped when the redundancy information indicates the word line is defective or unused.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: October 19, 2021
    Assignee: Micron Technology, Inc.
    Inventors: Bin Du, Liang Li, Yu Zhang, Yin Lu
  • Publication number: 20210260501
    Abstract: The disclosure provides an integrated separation unit for microplastics in the coastal sediments and a collection method of microplastics, belonging to the technical field of water treatment. The unit includes: a holder, a separation cylinder, a collection bottle, a central baffle plate, a baffle plate control knob, a stirring propeller, a motor, a cylinder switch, a filtration screen, a welding nozzle, a filter membrane and a vacuum pump. Using this unit for microplastic collection has the advantages of easy operation, economical and environment-friendly, high separation efficiency, and high durability.
    Type: Application
    Filed: September 23, 2020
    Publication date: August 26, 2021
    Inventors: Yin Lu, Wenyong WENG, Mingli YE, Qing MA, Xiaolu XU, Deyong ZHANG
  • Patent number: 10412137
    Abstract: Embodiments of the present invention provide a video processing method, a mobile terminal, and a server. The method may include: sending, by a mobile terminal, a request to a server for pulling status update data of a social network, so that the server acquires original status update data that is requested to be pulled, the original status update data including a source video address; performing, by the server, adaptation processing on the source video address, to generate an adaptive video address; updating, by the server, the original status update data by using the adaptive video address, to obtain optimized status update data, and returning the optimized status update data to the mobile terminal; and obtaining, by the mobile terminal, adaptive video data according to the adaptive video address in the optimized status update data, and playing the adaptive video data.
    Type: Grant
    Filed: June 8, 2015
    Date of Patent: September 10, 2019
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Huixing Wang, Zhihao Wang, Junhong Huang, Yin Lu, Minghui Wang, Haiyou Li, Shang Yu, Jun Lin, Yi Liu, Jiancheng Lin