Abstract: An anti-glare refractor for a luminaire may include an optic body having a light entrance side and a light exit side. The optic body may include a material characterized by an index of refraction. The light entrance side may include a substantially flat surface, and the light exit side may include a plurality of prisms each defined by a plurality of facet surfaces. Each facet surface may have a prism slope angle with respect to the substantially flat surface. The prism slope angle may be in a range from about 5 degrees to about 45 degrees.

Abstract: Examples are disclosed that relate to calibration data related to a determined alignment of sensors on a wearable display device. One example provides a wearable display device comprising a frame, a first sensor and a second sensor, one or more displays, a logic system, and a storage system. The storage system comprises calibration data related to a determined alignment of the sensors with the frame in a bent configuration and instructions executable by the logic system. The instructions are executable to obtain a first sensor data and a second sensor data respectfully from the first and second sensors, determine a distance from the wearable display device to a feature based at least upon the first and second sensor data using the calibration data, obtain a stereo image to display based upon the distance from the wearable display device to the feature, and output the stereo image via the displays.

Abstract: Silicone-containing light fixture optics. A method for manufacturing an optical component may include mixing two precursors of silicone, opening a first gate of an optic forming device, moving the silicone mixture from the extrusion machine into the optic forming device, cooling the silicone mixture as it enters the optic forming device, filling a mold within the optic forming device with the silicone mixture, closing the first gate, and heating the silicone mixture in the mold to at least partially cure the silicone. Alternatively, a method for manufacturing an optical component may include depositing a layer of heat cured silicone optical material to an optical structure, arranging one or more at least partially cured silicone optics on the layer of heat cured silicone optical material, and heating the heat cured silicone optical material to permanently adhere the one or more at least partially cured silicone optics to the optical structure.

Abstract: An anti-glare refractor for a luminaire may include an optic body having a light entrance side and a light exit side. The optic body may include a material characterized by an index of refraction. The light entrance side may include a substantially flat surface, and the light exit side may include a plurality of prisms each defined by a plurality of facet surfaces. Each facet surface may have a prism slope angle with respect to the substantially flat surface. The prism slope angle may be in a range from about 5 degrees to about 45 degrees.

Abstract: The present disclosure provides compositions of anti-ceramide antibodies and antigen-binding fragments thereof. The disclosure further provides methods of preventing or inhibiting cell death in a subject in need thereof comprising administering the anti-ceramide antibodies or antigen-binding fragments to a subject. The subject in need thereof may suffer from an autoimmune disease, GI syndrome, or GvHD.

Abstract: Disclosed herein are methods and compositions for disrupting an interaction between Galectin-3 and insulin receptor or integrins. Further disclosed herein are methods and compositions for the treatment of a disease or a disorder in a subject, such as the treatment of diabetes mellitus, inflammatory bowel syndrome, non-alcoholic fatty liver disease, and nonalcoholic steatohepatitis.

Abstract: A luminaire may include a light engine comprising a plurality of LEDs arranged in one or more annular rows. The luminaire may include an optic. The optic may include an annular optic body having a light entrance side facing the plurality of LEDs and a light exit side opposite the light entrance side. A plurality of annular grooves may be defined within the light exit side, the plurality of annular grooves being coaxial with the optic body. A plurality of arc-shaped grooves may be defined within the light exit side. Each of the plurality of arc-shaped grooves may be convex relative to a center of the optic. Each of the plurality of arc-shaped grooves may intersect at least one of the plurality of annular grooves. The optic may be configured to produce a Unified Glare Rating of less than 28.

Abstract: Disclosed herein are antibodies that specifically bind to Gal3 and methods of use thereof. In some embodiments, also described herein are methods of inducing immune activation or promoting T cell or Natural Killer cell proliferation with an antibody that specifically binds to Gal3. Also disclosed herein are methods and compositions of reducing fibrosis or propensity thereof in a tissue with antibodies that specifically bind to Gal3. In some cases, the anti-Gal3 antibody also disrupts the interaction between Gal3 and TIM-3.

Abstract: Examples are disclosed that relate to calibration data related to a determined alignment of sensors on a wearable display device. One example provides a wearable display device comprising a frame, a first sensor and a second sensor, one or more displays, a logic system, and a storage system. The storage system comprises calibration data related to a determined alignment of the sensors with the frame in a bent configuration and instructions executable by the logic system. The instructions are executable to obtain a first sensor data and a second sensor data respectfully from the first and second sensors, determine a distance from the wearable display device to a feature based at least upon the first and second sensor data using the calibration data, obtain a stereo image to display based upon the distance from the wearable display device to the feature, and output the stereo image via the displays.

Abstract: A luminaire may include a light engine comprising a plurality of LEDs arranged in one or more annular rows. The luminaire may include an optic. The optic may include an annular optic body having a light entrance side facing the plurality of LEDs and a light exit side opposite the light entrance side. A plurality of annular grooves may be defined within the light exit side, the plurality of annular grooves being coaxial with the optic body. A plurality of arc-shaped grooves may be defined within the light exit side. Each of the plurality of arc-shaped grooves may be convex relative to a center of the optic. Each of the plurality of arc-shaped grooves may intersect at least one of the plurality of annular grooves. The optic may be configured to produce a Unified Glare Rating of less than 28.

Abstract: Disclosed herein are antibodies that specifically bind to Gal3 and methods of use thereof. In some embodiments, also described herein are methods of inducing immune activation or promoting T cell or Natural Killer cell proliferation with an antibody that specifically binds to Gal3. Also disclosed herein are methods and compositions of reducing fibrosis or propensity thereof in a tissue with antibodies that specifically bind to Gal3. In some cases, the anti-Gal3 antibody also disrupts the interaction between Gal3 and TIM-3.

Abstract: Disclosed herein are antibodies that specifically bind to Gal3 and methods of use thereof. In some embodiments, also described herein are methods of inducing immune activation or promoting T cell or Natural Killer cell proliferation with an antibody that specifically binds to Gal3. Also disclosed herein are methods and compositions of reducing fibrosis or propensity thereof in a tissue with antibodies that specifically bind to Gal3. In some cases, the anti-Gal3 antibody also disrupts the interaction between Gal3 and TIM-3.

Abstract: Silicone-containing light fixture optics. A method for manufacturing an optical component may include mixing two precursors of silicone, opening a first gate of an optic forming device, moving the silicone mixture from the extrusion machine into the optic forming device, cooling the silicone mixture as it enters the optic forming device, filling a mold within the optic forming device with the silicone mixture, closing the first gate, and heating the silicone mixture in the mold to at least partially cure the silicone. Alternatively, a method for manufacturing an optical component may include depositing a layer of heat cured silicone optical material to an optical structure, arranging one or more at least partially cured silicone optics on the layer of heat cured silicone optical material, and heating the heat cured silicone optical material to permanently adhere the one or more at least partially cured silicone optics to the optical structure.

Abstract: A zirconium-based metal-organic framework material UiO-66(Zr) and a rapid room-temperature preparation method and application thereof are procided. The preparation method includes: (1) mixing a zirconium source and an organic ligand uniformly, then placing in methanol and stirring at room temperature, centrifuging and then discarding a supernatant to obtain a transparent gel-like intermediate product; and (2) heating and drying the intermediate product to obtain UiO-66(Zr). Compared with the prior art, the present invention excludes the use of N,N-dimethylformamide and other toxic organic solvents that are necessary in the traditional solvothermal method, and only needs to stir in methanol at room temperature and dry to obtain UiO-66(Zr). The method has mild conditions and a high yield. Moreover, the product purity is extremely high, and the product activation step can be omitted.

Abstract: A zirconium-based metal-organic framework material UiO-66(Zr) and a rapid room-temperature preparation method and application thereof are provided. The preparation method includes: (1) mixing a zirconium source and an organic ligand uniformly, then placing in methanol and stirring at room temperature, centrifuging and then discarding a supernatant to obtain a transparent gel-like intermediate product; and (2) heating and drying the intermediate product to obtain UiO-66(Zr). Compared with the prior art, the present invention excludes the use of N,N-dimethylformamide and other toxic organic solvents that are necessary in the traditional solvothermal method, and only needs to stir in methanol at room temperature and dry to obtain UiO-66(Zr). The method has mild conditions and a high yield. Moreover, the product purity is extremely high, and the product activation step can be omitted.

Abstract: Silicone-containing light fixture optics. A method for manufacturing an optical component may include mixing two precursors of silicone, opening a first gate of an optic forming device, moving the silicone mixture from the extrusion machine into the optic forming device, cooling the silicone mixture as it enters the optic forming device, filling a mold within the optic forming device with the silicone mixture, closing the first gate, and heating the silicone mixture in the mold to at least partially cure the silicone. Alternatively, a method for manufacturing an optical component may include depositing a layer of heat cured silicone optical material to an optical structure, arranging one or more at least partially cured silicone optics on the layer of heat cured silicone optical material, and heating the heat cured silicone optical material to permanently adhere the one or more at least partially cured silicone optics to the optical structure.

Abstract: Silicone-containing light fixture optics. A method for manufacturing an optical component may include mixing two precursors of silicone, opening a first gate of an optic forming device, moving the silicone mixture from the extrusion machine into the optic forming device, cooling the silicone mixture as it enters the optic forming device, filling a mold within the optic forming device with the silicone mixture, closing the first gate, and heating the silicone mixture in the mold to at least partially cure the silicone. Alternatively, a method for manufacturing an optical component may include depositing a layer of heat cured silicone optical material to an optical structure, arranging one or more at least partially cured silicone optics on the layer of heat cured silicone optical material, and heating the heat cured silicone optical material to permanently adhere the one or more at least partially cured silicone optics to the optical structure.

Abstract: Silicone-containing light fixture optics. A method for manufacturing an optical component may include mixing two precursors of silicone, opening a first gate of an optic forming device, moving the silicone mixture from the extrusion machine into the optic forming device, cooling the silicone mixture as it enters the optic forming device, filling a mold within the optic forming device with the silicone mixture, closing the first gate, and heating the silicone mixture in the mold to at least partially cure the silicone. Alternatively, a method for manufacturing an optical component may include depositing a layer of heat cured silicone optical material to an optical structure, arranging one or more at least partially cured silicone optics on the layer of heat cured silicone optical material, and heating the heat cured silicone optical material to permanently adhere the one or more at least partially cured silicone optics to the optical structure.

Abstract: Examples related to the incorporation of a sensor into an electronic device are disclosed. One example provides a system including a circuit board comprising a first side and a second side opposite the first side, a sensor housed in a package bonded to the first side of the circuit board, and a mounting pedestal coupled to the circuit board on the second side at a location opposite the package, the mounting pedestal configured to be mounted to a surface in an electronic device.

Abstract: Silicone-containing light fixture optics. A method for manufacturing an optical component may include mixing two precursors of silicone, opening a first gate of an optic forming device, moving the silicone mixture from the extrusion machine into the optic forming device, cooling the silicone mixture as it enters the optic forming device, filling a mold within the optic forming device with the silicone mixture, closing the first gate, and heating the silicone mixture in the mold to at least partially cure the silicone. Alternatively, a method for manufacturing an optical component may include depositing a layer of heat cured silicone optical material to an optical structure, arranging one or more at least partially cured silicone optics on the layer of heat cured silicone optical material, and heating the heat cured silicone optical material to permanently adhere the one or more at least partially cured silicone optics to the optical structure.