Abstract: The invention provides devices and methods for non-invasive monitoring and measuring of intraocular pressure (IOP) of a subject. Embodiments include a lens that is adapted to fit on the subject's eye, a microstructure disposed in or on the lens, the microstructure having at least one feature that exhibits a change in shape and/or geometry and/or position on the lens in response to a change in curvature of the lens. When the curvature of the lens changes in response to a change in IOP, a corresponding change in shape and/or geometry and/or position of the feature may be used to determine the change in IOP. The change in the feature is detectable in digital images of the lens taken with a mobile electronic device such as a smartphone.

Abstract: A pellet stove includes: a furnace; a burner disposed in the furnace, a top of the burner being open; and a feed opening provided at a first sidewall of the burner. A through port for air intake and ash falling is provided at an underside of the burner. A grate supporting pellet fuel is provided above the through port. Auxiliary supports for sustaining bottom fire are disposed under the grate. The auxiliary supports are arranged higher than the through port, and the auxiliary supports are located at a side below the feed opening and cover an area not exceeding ½ of the area covered by the grate.

Abstract: A method, computer system, and a computer program product are provided for post-modeling feature evaluation. In one embodiment, at least at least one post model visual output and associated data is obtained that at least includes an individual conditional expectation (ICE) plot and a partial dependence (PDP) plot. Using the associated data and the plots, a Feature Importance (PI) plot is provided. A plurality of features is then determined for each PI, PDP and ICE plots to calculate at least one Interesting Value for each plot. An overall score is also calculated for each plurality of features based on the associated Interesting Values for each PDP, ICE and PI plots. At least one top feature is selected based on said scores. A final plot is then generated at least reflecting the top feature. The final plot combines the PI, PDP and ICE plots together.

Abstract: A cassette and an embedding method using the same are provided. The cassette includes: a frame including an accommodating member, the accommodating member defining an accommodating chamber and configured to accommodate the tissue in the accommodating chamber, the accommodating chamber having a first opening and a second opening opposite to each other; a first holder detachably connected to the frame, and closing the first opening of the accommodating chamber; and a second holder connected to the frame, and configured to slide relative to the frame to open or close the second opening of the accommodating chamber.

Abstract: Provided are bispecific or multispecific antibodies that include an anti-CEACAM5 portion and one or more anti-4-1BB nanobodies whose agonist activity is dependent on the presence of the CEACAM5 antigen. Such bispecific or multispecific antibodies are safe, and are efficacious in treating cancer and have long-term protective immunological memory against tumors. Methods of using the antibodies for treating diseases such as cancer are also provided.

Abstract: An object detection method includes steps that are to be performed for each piece of point cloud data received from a lidar module, of selecting a first to-be-combined image from among images received from a camera device that corresponds in time to the piece of point cloud data, selecting a second to-be-combined image from among the images that is the Nth image before the first to-be-combined image in the time order, combining the first to-be-combined image and the second to-be-combined image to generate a combined image, generating a result image by incorporating the piece of point cloud data into the combined image, and inputting the result image into a trained machine learning model in order to determine a class to which each object in the result image belongs.

Abstract: There is provided a chromatography system comprising a first valve in fluid connection to a first chromatography column and/or a second valve; the second valve in fluid connection to a second chromatography column and the first valve; wherein the first valve and the second valve are operable to provide: a mode that selectively allows a fluid to flow from the first chromatography column to the second chromatography column; and one or more modes that selectively allows the fluid to bypass the first chromatography column and/or the second chromatography column. Also disclosed is a method of capturing and/or purifying a target from a sample thereof. In one embodiment, an acidic protein, alpha-1 anti-trypsin (A1AT), is purified by a tandem column configuration using anion exchange chromatography, whereby a first chromatography column is added in between the sample pump and an injection valve, or replaced the sample loop of AKTA system.

Abstract: Disclosed herein are embodiments of an Al—Ce—Cu alloy for use in additive manufacturing. The disclosed alloy embodiments provide fabricated objects, such as bulk components, comprising a heterogeneous microstructure and having good mechanical properties even when exposed to conditions used during the additive manufacturing process. Methods for making and using alloy embodiments also are disclosed herein.

Abstract: The present disclosure provides a dimming glass and a method for manufacturing the dimming glass. The dimming glass includes: at least one dimming functional layer sandwiched between two glass substrates, where a plurality of conductive leads is connected to a bonding circuit board, and a sealant filled between sealant regions of the two glass substrates. Each conductive lead includes a connecting end, a protruding end and an extension segment. The connecting end is connected to the bonding circuit board, the protruding end extends out of an outer side of an edge of the glass substrate, at least a part of the extension segment extends in a first direction which is an extension direction of an edge of the bonding side of the dimming functional layer, and the extension segment is located in the sealant region and is secured through the sealant.

Abstract: A multilayer optical film structure and a method of manufacturing the same are provided. The multilayer optical film structure includes a base layer, a first optical structure and a second optical structure. The base layer has a first surface and a second surface. The first optical structure is disposed on the first surface of the base layer. The second optical structure is disposed on the second surface of the base layer, and includes a first structural layer, a second structural layer and a third structural layer. The first structural layer is located between the base layer and the second structural layer, and the second structural layer is located between the first structural layer and the third structural layer. The difference between the refractive index of the first structural layer and the refractive index of the second structural layer is greater than or equal to 0.1.

Abstract: Provided in the present disclosure are a roller shutter tail cover and a roller shutter cover with the same. The roller shutter tail cover includes a cover body, a limit switch, and a limit device, where the limit switch is disposed on the cover body, and the limit device is connected to the limit switch. During motion of the roller shutter tail cover, when the limit switch is touched, the limit switch starts the limit device, and the limit device works to limit the motion of the roller shutter tail cover. During motion of the roller shutter tail cover, if the roller shutter tail cover touches other objects, the limit switch starts the limit device, and the limit device limits the motion of the roller shutter tail cover, thereby preventing the roller shutter tail cover from pinching other objects and lowering the safety risk.

Abstract: A semiconductor device and a method of manufacturing a semiconductor device are provided. The semiconductor device includes a semiconductor substrate, a trench, and a word line structure in the trench. The semiconductor substrate has a first active region and an isolation layer. The first active region includes a first sub-active region, a second sub-active region, and a first separation channel separating the first sub-active region from the second sub-active region. The word line structure is adjacent to the first active region and includes a word line insulating layer covering inner side surfaces of the trench, a word line electrode on the word line insulating layer, and a word line capping structure on the word line electrode. A depth of the first separation channel is substantially identical to a thickness of the isolation layer.

Abstract: A portable confocal optical scanning microscopic device includes an optical path module, a light source module, a light receiving module and an object stage, wherein the optical path module includes a beam splitter and a focusing lens; the light source module includes a light generator for generating an incident light and can be injected into the beam splitter; the light receiving module includes a spatial filter; the object stage is for setting a test specimen. The optical path module, the light source module, the light receiving module, and the object stage can be disassembled and assembled on the operating board to flexibly configure an adaptive combination capable of performing the optical scanning.

Abstract: The present disclosure provides a transparent display device, a simulation method, and a manufacturing method. The transparent display device includes a base substrate and a plurality of pixels arranged in an array form on the base substrate. Each pixel includes a transparent region and a display region, and a scattering structure for scattering light is arranged along a boundary between the transparent region and the display region.

Abstract: An application method of a rotary positioning device, which has a limit member, a rotary block and an elastic member mounted in a housing assembled at a preset panel with the steering shaft portion of the rotary block exposed outside the cover, and has the stopper of a docking shaft assembled at another preset panel inserted into the housing and the limit member to pass through two limiting balls and rest on the top of an accommodation chamber. Pulling up the steering shaft portion causes the elastic member to drive rotary slideways of the rotary block and rotation guides of the limit member to slide axially, so as to drive the accommodation chamber of the rotary block to rotate, push the two limiting balls into the slots of the limit member, and abut against the stopper, thus completing the assembly and positioning of the two preset panels.

Abstract: The present application discloses a semiconductor device and a method for fabricating the semiconductor device. The semiconductor device includes a substrate including a first peripheral region and a second peripheral region; a plurality of recessed gates respectively including a recessed gate dielectric layer inwardly positioned in the first peripheral region and including a U-shaped cross-sectional profile, a recessed gate bottom conductive layer positioned on the recessed gate dielectric layer and including a valley-shaped cross-sectional profile, resulting in a first valley, a recessed gate top conductive layer conformally positioned on the first valley of the recessed gate bottom conductive layer, and a recessed gate capping layer positioned on the recessed gate top conductive layer; and a peripheral gate structure positioned on the second peripheral region. An element density of the first peripheral region is greater than an element density of the second peripheral region.

Abstract: A solar cell module includes a first substrate, a second substrate, at least one cell unit, a first packaging film, a second packaging film, a first protective layer, a second protective layer, and a plurality of support members. The first substrate and the second substrate are disposed opposite to each other. The cell unit is disposed between the first substrate and the second substrate. The first packaging film is disposed between the cell unit and the first substrate. The second packaging film is disposed between the cell unit and the second substrate. The first protective layer is disposed between the cell unit and the first packaging film. The second protective layer is disposed between the cell unit and the second packaging film. The support members are respectively disposed between the first packaging film and the second packaging film and surround at least two opposite sides of the cell unit.