Patents by Inventor Ying-Chih Pu
Ying-Chih Pu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11471940Abstract: Provided are methods of producing cobalt nanoparticles (Co NPs). The methods include combining a cobalt salt, a capping agent, and a reducing agent, under Co NP synthesis conditions including a temperature selected to produce cobalt nanoparticles of a pre-selected diameter, where the temperature and pre-selected diameter are inversely related. In certain aspects, the methods further include producing hollow gold nano spheres (HGNs) using the cobalt nanoparticles as scaffolds. Also provided are cobalt nanoparticles and hollow gold nano spheres (HGNs) produced according to the present methods. Kits that find use in practicing the methods of the present disclosure are also provided.Type: GrantFiled: December 1, 2017Date of Patent: October 18, 2022Assignee: The Regents of the University of CaliforniaInventors: Ying-Chih Pu, Frank Song, Weichun Zhang, Sarah Lindley, Staci Adams, Jin Zhang
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Publication number: 20200114420Abstract: Provided are methods of producing cobalt nanoparticles (Co NPs). The methods include combining a cobalt salt, a capping agent, and a reducing agent, under Co NP synthesis conditions including a temperature selected to produce cobalt nanoparticles of a pre-selected diameter, where the temperature and pre-selected diameter are inversely related. In certain aspects, the methods further include producing hollow gold nano spheres (HGNs) using the cobalt nanoparticles as scaffolds. Also provided are cobalt nanoparticles and hollow gold nano spheres (HGNs) produced according to the present methods. Kits that find use in practicing the methods of the present disclosure are also provided.Type: ApplicationFiled: December 1, 2017Publication date: April 16, 2020Inventors: Ying-Chih Pu, Frank Song, Weichun Zhang, Sarah Lindley, Staci Adams, Jin Zhang
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Patent number: 9995683Abstract: An apparatus for detecting an object capable of emitting light. The apparatus includes a light source and a waveguide. The waveguide includes a core layer and a first cladding layer. At least one nanowell is formed in at least the first cladding layer. The apparatus further includes a light detector. The light detector can detect a light emitted from a single molecule object contained in the at least one nanowell.Type: GrantFiled: June 18, 2014Date of Patent: June 12, 2018Assignee: Industrial Technology Research InstituteInventors: Chung-Fan Chiou, Rung-Ywan Tsai, Yu-Tang Li, Chih-Tsung Shih, Ming-Chia Li, Chang-Sheng Chu, Shuang-Chao Chung, Jung-Po Chen, Ying-Chih Pu
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Patent number: 9777321Abstract: Embodiments encompass a single-molecule detection system and methods of using the detection system to detect an object. Further, embodiments encompass a detection system comprising a movable light coupler, a waveguide, and a light detector. Embodiments further encompass methods of single-molecule detection, including methods of single-molecule nucleic acid sequencing.Type: GrantFiled: September 9, 2016Date of Patent: October 3, 2017Assignee: Industrial Technology Research InstituteInventors: Chung-Fan Chiou, Ying-Chih Pu, Chao-Chi Pan, Chih-Tsung Shih, Ming-Chia Li, Chein-Shiu Kuo, Hung-Chi Chien, Chang-Sheng Chu
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Publication number: 20170009286Abstract: Embodiments encompass a single-molecule detection system and methods of using the detection system to detect an object. Further, embodiments encompass a detection system comprising a movable light coupler, a waveguide, and a light detector. Embodiments further encompass methods of single-molecule detection, including methods of single-molecule nucleic acid sequencing.Type: ApplicationFiled: September 9, 2016Publication date: January 12, 2017Inventors: Chung-Fan Chiou, Ying-Chih Pu, Chao-Chi Pan, Chih-Tsung Shih, Ming-Chia Li, Chein-Shiu Kuo, Hung-Chi Chien, Chang-Sheng Chu
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Patent number: 9482615Abstract: Embodiments encompass a single-molecule detection system and methods of using the detection system to detect an object. Further, embodiments encompass a detection system comprising a movable light coupler, a waveguide, and a light detector. Embodiments further encompass methods of single-molecule detection, including methods of single-molecule nucleic acid sequencing.Type: GrantFiled: March 11, 2011Date of Patent: November 1, 2016Assignee: Industrial Technology Research InstituteInventors: Chung-Fan Chiou, Ying-Chih Pu, Chao-Chi Pan, Chih-Tsung Shih, Ming-Chia Li, Chein-Shiu Kuo, Hung-Chi Chien, Chang-Sheng Chu
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Publication number: 20140367589Abstract: An apparatus for detecting an object capable of emitting light. The apparatus includes a light source and a waveguide. The waveguide includes a core layer and a first cladding layer. At least one nanowell is formed in at least the first cladding layer. The apparatus further includes a light detector. The light detector can detect a light emitted from a single molecule object contained in the at least one nanowell.Type: ApplicationFiled: June 18, 2014Publication date: December 18, 2014Inventors: Chung-Fan Chiou, Rung-Ywan Tsai, Yu-Tang Li, Chih-Tsung Shih, Ming-Chia Li, Chang-Sheng Chu, Shuang-Chao Chung, Jung-Po Chen, Ying-Chih Pu
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Patent number: 8865077Abstract: An apparatus for detecting an object capable of emitting light. The apparatus comprises a light source and a waveguide. The waveguide comprises a core layer and a first cladding layer. At least one nanowell is formed in at least the first cladding layer. The apparatus further comprises a light detector. The light detector can detect a light emitted from a single molecule object contained in the at least one nanowell.Type: GrantFiled: June 11, 2010Date of Patent: October 21, 2014Assignee: Industrial Technology Research InstituteInventors: Chung-Fan Chiou, Rung-Ywan Tsai, Yu-Tang Li, Chih-Tsung Shih, Ming-Chia Li, Chang-Sheng Chu, Shuang-Chao Chung, Jung-Po Chen, Ying-Chih Pu
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Patent number: 8865078Abstract: An apparatus for detecting an object capable of emitting light. The apparatus includes a light source and a waveguide. The waveguide includes a core layer and a first cladding layer. At least one nanowell is formed in at least the first cladding layer. The apparatus further includes a light detector. The light detector can detect a light emitted from a single molecule object contained in the at least one nanowell.Type: GrantFiled: July 29, 2010Date of Patent: October 21, 2014Assignee: Industrial Technology Research InstituteInventors: Chung-Fan Chiou, Rung-Ywan Tsai, Yu-Tang Li, Chih-Tsung Shih, Ming-Chia Li, Chang-Sheng Chu, Shuang-Chao Chung, Jung-Po Chen, Ying-Chih Pu
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Patent number: 8721969Abstract: An apparatus for detecting an object capable of emitting light. The apparatus comprises a light source and a waveguide. The waveguide comprises a core layer and a first cladding layer. At least one nanowell is formed in at least the first cladding layer. The apparatus further comprises a light detector. The light detector can detect a light emitted from a single molecule object contained in the at least one nanowell.Type: GrantFiled: June 11, 2010Date of Patent: May 13, 2014Assignee: Industrial Technology Research InstituteInventors: Chung-Fan Chiou, Rung-Ywan Tsai, Yu-Tang Li, Chih-Tsung Shih, Ming-Chia Li, Chang-Sheng Chu, Shuang-Chao Chung, Jung-Po Chen, Ying-Chih Pu
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Patent number: 8368106Abstract: Method of manufacturing gradient composite material comprises steps of providing plural surface modified inorganic nanoparticles with functional groups or oligomers with functional groups; transferring the surface modified inorganic nanoparticles or oligomers with functional groups into an organic matrix to form a mixture; performing a photo polymerization step or a thermo-polymerization step for polymerizing and generating a gradient distribution of the surface modified inorganic nanoparticles or oligomers with functional groups in the mixture; and curing the mixture to solidify the organic matrix and form a structure with gradient composite, wherein the organic matrix is transferred into an organic polymer after curing.Type: GrantFiled: November 4, 2010Date of Patent: February 5, 2013Assignee: Industrial Technology Research InstituteInventors: Guang-Way Jang, Ying-Chih Pu, Yin-Ju Yang, Chang-Ming Wong, Chih-Fen Chang
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Publication number: 20120112219Abstract: Method of manufacturing gradient composite material comprises steps of providing plural surface modified inorganic nanoparticles with functional groups or oligomers with functional groups; transferring the surface modified inorganic nanoparticles or oligomers with functional groups into an organic matrix to form a mixture; performing a photo polymerization step or a thermo-polymerization step for polymerizing and generating a gradient distribution of the surface modified inorganic nanoparticles or oligomers with functional groups in the mixture; and curing the mixture to solidify the organic matrix and form a structure with gradient composite, wherein the organic matrix is transferred into an organic polymer after curing.Type: ApplicationFiled: November 4, 2010Publication date: May 10, 2012Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Guang-Way Jang, Ying-Chih Pu, Yin-Ju Yang, Chang-Ming Wong, Chih-Fen Chang
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Publication number: 20110306039Abstract: An apparatus for detecting an object capable of emitting light. The apparatus comprises a light source and a waveguide. The waveguide comprises a core layer and a first cladding layer. At least one nanowell is formed in at least the first cladding layer. The apparatus further comprises a light detector. The light detector can detect a light emitted from a single molecule object contained in the at least one nanowell.Type: ApplicationFiled: June 11, 2010Publication date: December 15, 2011Inventors: Chung-Fan Chiou, Rung-Ywan Tsai, Yu-Tang Li, Chih-Tsung Shih, Ming-Chia Li, Chang-Sheng Chu, Shuang-Chao Chung, Jung-Po Chen, Ying-Chih Pu
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Publication number: 20110306143Abstract: An apparatus for detecting an object capable of emitting light. The apparatus includes a light source and a waveguide. The waveguide includes a core layer and a first cladding layer. At least one nanowell is formed in at least the first cladding layer. The apparatus further includes a light detector. The light detector can detect a light emitted from a single molecule object contained in the at least one nanowell.Type: ApplicationFiled: July 29, 2010Publication date: December 15, 2011Inventors: Chung-Fan Chiou, Rung-Ywan Tsai, Yu-Tang Li, Chih-Tsung Shih, Ming-Chia Li, Chang-Sheng Chu, Shuang-Chao Chung, Jung-Po Chen, Ying-Chih Pu
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Publication number: 20110223590Abstract: Embodiments encompass a single-molecule detection system and methods of using the detection system to detect an object. Further, embodiments encompass a detection system comprising a movable light coupler, a waveguide, and a light detector. Embodiments further encompass methods of single-molecule detection, including methods of single-molecule nucleic acid sequencing.Type: ApplicationFiled: March 11, 2011Publication date: September 15, 2011Applicant: Industrial Technology Research InstituteInventors: Chung-Fan CHIOU, Ying-Chih Pu, Chao-Chi Pan, Chih-Tsung Shih, Ming-Chia Li, Chein-Shiu Kuo, Hung-Chi Chien, Chang-Sheng Chu