Abstract: The present discussion relates to the delivery of ultrasonic therapy energy to a target region in conjunction with a clear path determination that may assess one or more of: (1) presence of non-soft tissue regions within the therapy beam path (e.g., bone or bone-like structures, gas-filled cavities, and so forth), (2) partial “lift-off” of the probe head; or (3) sufficiency of acoustic coupling. Upon determination or confirmation of at least a partial clear path with respect to some or all of these factors, the therapy beam may be delivered to the target region.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation that include applying energy (e.g., ultrasound energy) into an internal tissue to cause tissue displacement and identifying that the tissue displacement has occurred. In one embodiment, the presence of tissue displacement is associated with a desired therapeutic or physiological outcome, such as a change in a molecule of interest.

Abstract: The present discussion relates to the delivery of ultrasonic therapy energy to a target region in conjunction with a clear path determination that may assess one or more of: (1) presence of non-soft tissue regions within the therapy beam path (e.g., bone or bone-like structures, gas-filled cavities, and so forth), (2) partial “lift-off” of the probe head; or (3) sufficiency of acoustic coupling. Upon determination or confirmation of at least a partial clear path with respect to some or all of these factors, the therapy beam may be delivered to the target region.

Abstract: Embodiments of the present disclosure relate to techniques for facilitating personalized neuromodulation treatment protocols. In one embodiment, a predetermined treatment position of an energy application device is used to guide future treatments for the patient. In one embodiment, a position of the energy application device relative to the predetermined treatment position is determined. In one embodiment, a total dose of ultrasound energy applied to the region of interest is determined.

Abstract: The present invention provides an endoscope, which includes a catheter, a handle, an instrument tube, a linkage unit, a controlling unit, cables, tension units, and a tension adjusting unit. One end of the catheter is provided with a lens, and the other end of the catheter is extended into the handle. One part of the instrument tube is disposed in the handle and is connected with the other end of the catheter. The other part of the instrument tube is exposed outside the handle. The linkage unit is disposed in the handle. The controlling unit is disposed outside the handle and is extended into the handle to be pivotally connected with the linkage unit. One end of the cable is connected to the linkage unit, and the other end thereof is connected to one end periphery of the catheter. One end of the tension unit is connected to the periphery of the cable. The tension adjusting unit is provided with adjusting members and connection members.

Abstract: A pharmaceutical formulation which comprises Compound 1, one or more pharmaceutical fillers, one or more pharmaceutical disintegrants, and one or more pharmaceutical lubricant.

Abstract: Embodiments of the present disclosure relate to techniques for facilitating personalized neuromodulation treatment protocols. In one embodiment, a predetermined treatment position of an energy application device is used to guide future treatments for the patient. In one embodiment, a position of the energy application device relative to the predetermined treatment position is determined. In one embodiment, a total dose of ultrasound energy applied to the region of interest is determined.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation of a tissue that include applying energy (e.g., ultrasound energy) into the tissue to cause altered activity at a synapse between a neuron and a non-neuronal cell.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation that include applying energy (e.g., ultrasound energy) into an internal tissue to cause tissue displacement and identifying that the tissue displacement has occurred. In one embodiment, the presence of tissue displacement is associated with a desired therapeutic or physiological outcome, such as a change in a molecule of interest.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation that include applying energy (e.g., ultrasound energy) into an internal tissue to cause tissue displacement and identifying that the tissue displacement has occurred. In one embodiment, the presence of tissue displacement is associated with a desired therapeutic or physiological outcome, such as a change in a molecule of interest.

Abstract: A steering joint comprises a first tubular member and a second tubular member. The first tubular member and the second tubular member include a plurality of cuts to facilitate bending. One end of the first tubular member has an accommodation portion for accommodating an endoscopic image module, and the other end has a first joint portion. One end of the second tubular member has a second joint portion which is joined to the first joint portion of the first tubular member. The tubular member of the steering joint is easy to injection mold and can reduce the accumulated tolerance. An endoscope including the abovementioned steering joint is also disclosed.

Abstract: Disclosed is a monoclonal antibody or an antigen binding fragment thereof which targets tissue factor pathway inhibitor (TFPI), and a medical use thereof.

Abstract: The present discussion relates to the delivery of ultrasonic therapy energy to a target region in conjunction with a clear path determination that may assess one or more of: (1) presence of non-soft tissue regions within the therapy beam path (e.g., bone or bone-like structures, gas-filled cavities, and so forth), (2) partial “lift-off” of the probe head; or (3) sufficiency of acoustic coupling. Upon determination or confirmation of at least a partial clear path with respect to some or all of these factors, the therapy beam may be delivered to the target region.

Abstract: Embodiments of the present disclosure relate to techniques for facilitating personalized neuromodulation treatment protocols. In one embodiment, a predetermined treatment position of an energy application device is used to guide future treatments for the patient. In one embodiment, a position of the energy application device relative to the predetermined treatment position is determined. In one embodiment, a total dose of ultrasound energy applied to the region of interest is determined.

Abstract: A cleaning system and method use an ultrasound probe, a coupling mechanism, and a controller to clean equipment of a vehicle system. The ultrasound probe enters into an engine. The ultrasound probe emits ultrasound pulses and the coupling mechanism provides an ultrasound coupling medium between the ultrasound probe and one or more components of the engine. The controller drives the ultrasound probe to deliver the ultrasound pulse through the coupling medium to a surface of the one or more components of the engine. The ultrasound probe delivers the ultrasound pulse to remove deposits from the one or more components of the engine.

Abstract: Embodiments of the present disclosure relate to techniques for facilitating personalized neuromodulation treatment protocols. In one embodiment, a predetermined treatment position of an energy application device is used to guide future treatments for the patient. In one embodiment, a position of the energy application device relative to the predetermined treatment position is determined. In one embodiment, a total dose of ultrasound energy applied to the region of interest is determined.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation that include applying energy (e.g., ultrasound energy) into an internal tissue to cause tissue displacement and identifying that the tissue displacement has occurred. In one embodiment, the presence of tissue displacement is associated with a desired therapeutic or physiological outcome, such as a change in a molecule of interest.

Abstract: A smart adjustment system is provided, which may include a cloud computing device and a data acquisition device. The cloud computing device may include a neural network model saving the model data of machine tools, and the estimated increase percentages of each machine tool in different cutting parameters. The data acquisition device may receive the model data of a target machine tool. The could computing device may compare the model data of the target machine tool with the model data of the machine tools via the neural network model in order to calculate an estimated cutting parameter with an estimated increase percentage and control the target machine tool to perform a machining process by the estimated cutting parameter.

Abstract: A portable machine health monitoring system, applied for diagnosing a machine in operation, includes an installation device and a portable monitoring box. The installation device includes a plurality of sensing assemblies and a plurality of connecting assemblies. Each of the plurality of sensing assemblies is connected with the corresponding connecting assembly. Each of the plurality of connecting assemblies mounts the corresponding sensing assembly in a non-destructive manner onto a detected position on the machine. Each of the plurality of sensing assemblies is used for detecting a motion signal at the corresponding detected position on the machine in operation. The portable monitoring box, connected with the installation device, includes an analysis module for receiving the motion signal and further for calculating a health status information according to the detected motion signal.